BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 19844931)

  • 1. Cortistatin A is a high-affinity ligand of protein kinases ROCK, CDK8, and CDK11.
    Cee VJ; Chen DY; Lee MR; Nicolaou KC
    Angew Chem Int Ed Engl; 2009; 48(47):8952-7. PubMed ID: 19844931
    [No Abstract]   [Full Text] [Related]  

  • 2. Fragment-based discovery of 6-substituted isoquinolin-1-amine based ROCK-I inhibitors.
    Ray P; Wright J; Adam J; Bennett J; Boucharens S; Black D; Cook A; Brown AR; Epemolu O; Fletcher D; Haunso A; Huggett M; Jones P; Laats S; Lyons A; Mestres J; de Man J; Morphy R; Rankovic Z; Sherborne B; Sherry L; van Straten N; Westwood P; Zaman GZ
    Bioorg Med Chem Lett; 2011 Jan; 21(1):97-101. PubMed ID: 21145740
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the mediator subunit cyclin C and its implications for CDK8 function.
    Hoeppner S; Baumli S; Cramer P
    J Mol Biol; 2005 Jul; 350(5):833-42. PubMed ID: 15979093
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transcriptional kinases: Less is more (or less).
    Boyer TG
    Nat Chem Biol; 2016 Jan; 12(1):4-5. PubMed ID: 26678610
    [No Abstract]   [Full Text] [Related]  

  • 5. The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder.
    Schneider EV; Böttcher J; Blaesse M; Neumann L; Huber R; Maskos K
    J Mol Biol; 2011 Sep; 412(2):251-66. PubMed ID: 21806996
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A novel computational analysis of ligand-induced conformational changes in the ATP binding sites of cyclin dependent kinases.
    Subramanian J; Sharma S; B-Rao C
    J Med Chem; 2006 Sep; 49(18):5434-41. PubMed ID: 16942017
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II.
    Elmlund H; Baraznenok V; Lindahl M; Samuelsen CO; Koeck PJ; Holmberg S; Hebert H; Gustafsson CM
    Proc Natl Acad Sci U S A; 2006 Oct; 103(43):15788-93. PubMed ID: 17043218
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intramolecular cyclopropene-furan [2 + 4] cycloaddition followed by a cyclopropylcarbinyl rearrangement to synthesize the BCD rings of cortistatin A.
    Magnus P; Littich R
    Org Lett; 2009 Sep; 11(17):3938-41. PubMed ID: 19655736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human mediator kinase subunit CDK11 plays a negative role in viral activator VP16-dependent transcriptional regulation.
    Tsutsui T; Umemura H; Tanaka A; Mizuki F; Hirose Y; Ohkuma Y
    Genes Cells; 2008 Aug; 13(8):817-26. PubMed ID: 18651850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Picture story. Reining in CDK.
    Feng H
    Nat Struct Biol; 2001 May; 8(5):391. PubMed ID: 11323710
    [No Abstract]   [Full Text] [Related]  

  • 11. HIV Transcription Is Independent of Mediator Kinases.
    Cary DC; Rheinberger M; Rojc A; Peterlin BM
    AIDS Res Hum Retroviruses; 2019 Aug; 35(8):710-717. PubMed ID: 31044597
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.
    Vaasa A; Viil I; Enkvist E; Viht K; Raidaru G; Lavogina D; Uri A
    Anal Biochem; 2009 Feb; 385(1):85-93. PubMed ID: 19017524
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Integration of virtual screening with high-throughput screening for the identification of novel Rho-kinase I inhibitors.
    Gong LL; Fang LH; Peng JH; Liu AL; Du GH
    J Biotechnol; 2010 Feb; 145(3):295-303. PubMed ID: 19963024
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characteristics of the Plasmodium falciparum PK5 ATP-binding site: implications for the design of novel antimalarial agents.
    Keenan SM; Welsh WJ
    J Mol Graph Model; 2004 Jan; 22(3):241-7. PubMed ID: 14629982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The cyclin-dependent kinase 11 interacts with 14-3-3 proteins.
    Feng Y; Qi W; Martinez J; Nelson MA
    Biochem Biophys Res Commun; 2005 Jun; 331(4):1503-9. PubMed ID: 15883043
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-guided discovery of cyclin-dependent kinase inhibitors.
    Fischmann TO; Hruza A; Duca JS; Ramanathan L; Mayhood T; Windsor WT; Le HV; Guzi TJ; Dwyer MP; Paruch K; Doll RJ; Lees E; Parry D; Seghezzi W; Madison V
    Biopolymers; 2008 May; 89(5):372-9. PubMed ID: 17937404
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cell cycle. Confirmational change.
    Pines J
    Nature; 1995 Jul; 376(6538):294-5. PubMed ID: 7630391
    [No Abstract]   [Full Text] [Related]  

  • 18. Substituted 2H-isoquinolin-1-ones as potent Rho-kinase inhibitors: part 3, aryl substituted pyrrolidines.
    Bosanac T; Hickey ER; Ginn J; Kashem M; Kerr S; Kugler S; Li X; Olague A; Schlyer S; Young ER
    Bioorg Med Chem Lett; 2010 Jun; 20(12):3746-9. PubMed ID: 20471253
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Combinatorial ligand design targeted at protein families.
    Todorov NP; Buenemann CL; Alberts IL
    J Chem Inf Model; 2005; 45(2):314-20. PubMed ID: 15807493
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk.
    Woodard CL; Keenan SM; Gerena L; Welsh WJ; Geyer JA; Waters NC
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4961-6. PubMed ID: 17588749
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.