316 related articles for article (PubMed ID: 19850877)
1. Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.
Hasumi Y; Baba M; Ajima R; Hasumi H; Valera VA; Klein ME; Haines DC; Merino MJ; Hong SB; Yamaguchi TP; Schmidt LS; Linehan WM
Proc Natl Acad Sci U S A; 2009 Nov; 106(44):18722-7. PubMed ID: 19850877
[TBL] [Abstract][Full Text] [Related]
2. Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys.
Baba M; Furihata M; Hong SB; Tessarollo L; Haines DC; Southon E; Patel V; Igarashi P; Alvord WG; Leighty R; Yao M; Bernardo M; Ileva L; Choyke P; Warren MB; Zbar B; Linehan WM; Schmidt LS
J Natl Cancer Inst; 2008 Jan; 100(2):140-54. PubMed ID: 18182616
[TBL] [Abstract][Full Text] [Related]
3. Birt-Hogg-Dubé syndrome: Clinical and molecular aspects of recently identified kidney cancer syndrome.
Hasumi H; Baba M; Hasumi Y; Furuya M; Yao M
Int J Urol; 2016 Mar; 23(3):204-10. PubMed ID: 26608100
[TBL] [Abstract][Full Text] [Related]
4. Folliculin encoded by the BHD gene interacts with a binding protein, FNIP1, and AMPK, and is involved in AMPK and mTOR signaling.
Baba M; Hong SB; Sharma N; Warren MB; Nickerson ML; Iwamatsu A; Esposito D; Gillette WK; Hopkins RF; Hartley JL; Furihata M; Oishi S; Zhen W; Burke TR; Linehan WM; Schmidt LS; Zbar B
Proc Natl Acad Sci U S A; 2006 Oct; 103(42):15552-7. PubMed ID: 17028174
[TBL] [Abstract][Full Text] [Related]
5. Renal tumour suppressor function of the Birt-Hogg-Dubé syndrome gene product folliculin.
Hudon V; Sabourin S; Dydensborg AB; Kottis V; Ghazi A; Paquet M; Crosby K; Pomerleau V; Uetani N; Pause A
J Med Genet; 2010 Mar; 47(3):182-9. PubMed ID: 19843504
[TBL] [Abstract][Full Text] [Related]
6. Deficiency of FLCN in mouse kidney led to development of polycystic kidneys and renal neoplasia.
Chen J; Futami K; Petillo D; Peng J; Wang P; Knol J; Li Y; Khoo SK; Huang D; Qian CN; Zhao P; Dykema K; Zhang R; Cao B; Yang XJ; Furge K; Williams BO; Teh BT
PLoS One; 2008; 3(10):e3581. PubMed ID: 18974783
[TBL] [Abstract][Full Text] [Related]
7. Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases.
Petersson F; Gatalica Z; Grossmann P; Perez Montiel MD; Alvarado Cabrero I; Bulimbasic S; Swatek A; Straka L; Tichy T; Hora M; Kuroda N; Legendre B; Michal M; Hes O
Virchows Arch; 2010 Apr; 456(4):355-65. PubMed ID: 20300772
[TBL] [Abstract][Full Text] [Related]
8. Tumor suppressor FLCN inhibits tumorigenesis of a FLCN-null renal cancer cell line and regulates expression of key molecules in TGF-beta signaling.
Hong SB; Oh H; Valera VA; Stull J; Ngo DT; Baba M; Merino MJ; Linehan WM; Schmidt LS
Mol Cancer; 2010 Jun; 9():160. PubMed ID: 20573232
[TBL] [Abstract][Full Text] [Related]
9. Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
Chen J; Huang D; Rubera I; Futami K; Wang P; Zickert P; Khoo SK; Dykema K; Zhao P; Petillo D; Cao B; Zhang Z; Si S; Schoen SR; Yang XJ; Zhou M; Xiao GQ; Wu G; Nordenskjöld M; Tauc M; Williams BO; Furge KA; Teh BT
Kidney Int; 2015 Nov; 88(5):1057-69. PubMed ID: 26083655
[TBL] [Abstract][Full Text] [Related]
10. Novel mutations in the BHD gene and absence of loss of heterozygosity in fibrofolliculomas of Birt-Hogg-Dubé patients.
van Steensel MA; Verstraeten VL; Frank J; Kelleners-Smeets NW; Poblete-Gutiérrez P; Marcus-Soekarman D; Bladergroen RS; Steijlen PM; van Geel M
J Invest Dermatol; 2007 Mar; 127(3):588-93. PubMed ID: 17124507
[TBL] [Abstract][Full Text] [Related]
11. The role of the Birt-Hogg-Dubé protein in mTOR activation and renal tumorigenesis.
Hartman TR; Nicolas E; Klein-Szanto A; Al-Saleem T; Cash TP; Simon MC; Henske EP
Oncogene; 2009 Apr; 28(13):1594-604. PubMed ID: 19234517
[TBL] [Abstract][Full Text] [Related]
12. Tumor Suppressor Folliculin Regulates mTORC1 through Primary Cilia.
Zhong M; Zhao X; Li J; Yuan W; Yan G; Tong M; Guo S; Zhu Y; Jiang Y; Liu Y; Jiang Y
J Biol Chem; 2016 May; 291(22):11689-97. PubMed ID: 27072130
[TBL] [Abstract][Full Text] [Related]
13. Distinctive expression patterns of glycoprotein non-metastatic B and folliculin in renal tumors in patients with Birt-Hogg-Dubé syndrome.
Furuya M; Hong SB; Tanaka R; Kuroda N; Nagashima Y; Nagahama K; Suyama T; Yao M; Nakatani Y
Cancer Sci; 2015 Mar; 106(3):315-23. PubMed ID: 25594584
[TBL] [Abstract][Full Text] [Related]
14. Knockdown of Slingshot 2 (SSH2) serine phosphatase induces Caspase3 activation in human carcinoma cell lines with the loss of the Birt-Hogg-Dubé tumour suppressor gene (FLCN).
Lu X; Boora U; Seabra L; Rabai EM; Fenton J; Reiman A; Nagy Z; Maher ER
Oncogene; 2014 Feb; 33(8):956-65. PubMed ID: 23416984
[TBL] [Abstract][Full Text] [Related]
15. Pulmonary cysts of Birt-Hogg-Dubé syndrome: a clinicopathologic and immunohistochemical study of 9 families.
Furuya M; Tanaka R; Koga S; Yatabe Y; Gotoda H; Takagi S; Hsu YH; Fujii T; Okada A; Kuroda N; Moritani S; Mizuno H; Nagashima Y; Nagahama K; Hiroshima K; Yoshino I; Nomura F; Aoki I; Nakatani Y
Am J Surg Pathol; 2012 Apr; 36(4):589-600. PubMed ID: 22441547
[TBL] [Abstract][Full Text] [Related]
16. Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Wu M; Si S; Li Y; Schoen S; Xiao GQ; Li X; Teh BT; Wu G; Chen J
Oncotarget; 2015 Oct; 6(32):32761-73. PubMed ID: 26418749
[TBL] [Abstract][Full Text] [Related]
17. Birt-Hogg-Dubé syndrome: clinicopathologic findings and genetic alterations.
Adley BP; Smith ND; Nayar R; Yang XJ
Arch Pathol Lab Med; 2006 Dec; 130(12):1865-70. PubMed ID: 17149965
[TBL] [Abstract][Full Text] [Related]
18. Therapeutic targeting the loss of the birt-hogg-dube suppressor gene.
Lu X; Wei W; Fenton J; Nahorski MS; Rabai E; Reiman A; Seabra L; Nagy Z; Latif F; Maher ER
Mol Cancer Ther; 2011 Jan; 10(1):80-9. PubMed ID: 21220493
[TBL] [Abstract][Full Text] [Related]
19. Unique mutation, accelerated mTOR signaling and angiogenesis in the pulmonary cysts of Birt-Hogg-Dubé syndrome.
Nishii T; Tanabe M; Tanaka R; Matsuzawa T; Okudela K; Nozawa A; Nakatani Y; Furuya M
Pathol Int; 2013 Jan; 63(1):45-55. PubMed ID: 23356225
[TBL] [Abstract][Full Text] [Related]
20. Fluorescent and chromogenic in situ hybridization of CEN17q as a potent useful diagnostic marker for Birt-Hogg-Dubé syndrome-associated chromophobe renal cell carcinomas.
Kato I; Iribe Y; Nagashima Y; Kuroda N; Tanaka R; Nakatani Y; Hasumi H; Yao M; Furuya M
Hum Pathol; 2016 Jun; 52():74-82. PubMed ID: 26980015
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]