BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

69 related articles for article (PubMed ID: 19850982)

  • 1. Folate deficiency followed by ionizing radiation perturbs hepatic dihydrofolate reducatse activity.
    Batra V; Lakhmy S; Devasagayam TP
    Biofactors; 2008; 34(4):273-83. PubMed ID: 19850982
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interaction between cytotoxic effects of gamma-radiation and folate deficiency in relation to choline reserves.
    Batra V; Devasagayam TP
    Toxicology; 2009 Jan; 255(1-2):91-9. PubMed ID: 19010378
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folate deficiency and in vitro palatogenesis II: Effects of methotrexate on rabbit palate fusion, folate pools, and dihydrofolate reductase activity.
    DePaola DP; Mandella RD
    J Craniofac Genet Dev Biol; 1984; 4(4):321-7. PubMed ID: 6520212
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases--inhibition by folic acid and polyphenols.
    Kao TT; Wang KC; Chang WN; Lin CY; Chen BH; Wu HL; Shi GY; Tsai JN; Fu TF
    Drug Metab Dispos; 2008 Mar; 36(3):508-16. PubMed ID: 18056255
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Engineering specificity for folate into dihydrofolate reductase from Escherichia coli.
    Posner BA; Li L; Bethell R; Tsuji T; Benkovic SJ
    Biochemistry; 1996 Feb; 35(5):1653-63. PubMed ID: 8634297
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular genetic analysis of the human dihydrofolate reductase gene: relation with plasma total homocysteine, serum and red blood cell folate levels.
    Gellekink H; Blom HJ; van der Linden IJ; den Heijer M
    Eur J Hum Genet; 2007 Jan; 15(1):103-9. PubMed ID: 16969375
    [TBL] [Abstract][Full Text] [Related]  

  • 7. New 2,4-diamino-5-(2',5'-substituted benzyl)pyrimidines as potential drugs against opportunistic infections of AIDS and other immune disorders. Synthesis and species-dependent antifolate activity.
    Rosowsky A; Forsch RA; Sibley CH; Inderlied CB; Queener SF
    J Med Chem; 2004 Mar; 47(6):1475-86. PubMed ID: 14998335
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Repair of radiation-induced DNA strand breaks does not occur preferentially in transcriptionally active DNA.
    Ljungman M
    Radiat Res; 1999 Oct; 152(4):444-9. PubMed ID: 10477922
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Molecular mechanisms of adaptation to folate deficiency.
    Ifergan I; Assaraf YG
    Vitam Horm; 2008; 79():99-143. PubMed ID: 18804693
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Further studies on 2,4-diamino-5-(2',5'-disubstituted benzyl)pyrimidines as potent and selective inhibitors of dihydrofolate reductases from three major opportunistic pathogens of AIDS.
    Rosowsky A; Forsch RA; Queener SF
    J Med Chem; 2003 Apr; 46(9):1726-36. PubMed ID: 12699390
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cell cycle phase dependent role of DNA polymerase beta in DNA repair and survival after ionizing radiation.
    Vermeulen C; Verwijs-Janssen M; Begg AC; Vens C
    Radiother Oncol; 2008 Mar; 86(3):391-8. PubMed ID: 18237797
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MAPK dependence of DNA damage repair: ionizing radiation and the induction of expression of the DNA repair genes XRCC1 and ERCC1 in DU145 human prostate carcinoma cells in a MEK1/2 dependent fashion.
    Yacoub A; Park JS; Qiao L; Dent P; Hagan MP
    Int J Radiat Biol; 2001 Oct; 77(10):1067-78. PubMed ID: 11682011
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet.
    Bagnyukova TV; Powell CL; Pavliv O; Tryndyak VP; Pogribny IP
    Brain Res; 2008 Oct; 1237():44-51. PubMed ID: 18694737
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The antifolate activity of tea catechins.
    Navarro-Perán E; Cabezas-Herrera J; García-Cánovas F; Durrant MC; Thorneley RN; Rodríguez-López JN
    Cancer Res; 2005 Mar; 65(6):2059-64. PubMed ID: 15781612
    [TBL] [Abstract][Full Text] [Related]  

  • 15. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
    Shih C; Chen VJ; Gossett LS; Gates SB; MacKellar WC; Habeck LL; Shackelford KA; Mendelsohn LG; Soose DJ; Patel VF; Andis SL; Bewley JR; Rayl EA; Moroson BA; Beardsley GP; Kohler W; Ratnam M; Schultz RM
    Cancer Res; 1997 Mar; 57(6):1116-23. PubMed ID: 9067281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei.
    Beetstra S; Thomas P; Salisbury C; Turner J; Fenech M
    Mutat Res; 2005 Oct; 578(1-2):317-26. PubMed ID: 16005909
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interactions between folate metabolism, phenytoin metabolism, and liver microsomal cytochrome P450.
    Billings RE
    Drug Nutr Interact; 1984; 3(1):21-32. PubMed ID: 6510238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
    Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
    Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Folate deprivation promotes mitochondrial oxidative decay: DNA large deletions, cytochrome c oxidase dysfunction, membrane depolarization and superoxide overproduction in rat liver.
    Chang CM; Yu CC; Lu HT; Chou YF; Huang RF
    Br J Nutr; 2007 May; 97(5):855-63. PubMed ID: 17381984
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of folic acid deficiency and MTHFR C677T polymorphism on spontaneous and radiation-induced micronuclei in human lymphocytes.
    Leopardi P; Marcon F; Caiola S; Cafolla A; Siniscalchi E; Zijno A; Crebelli R
    Mutagenesis; 2006 Sep; 21(5):327-33. PubMed ID: 16950805
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.