282 related articles for article (PubMed ID: 19854946)
1. DNA topoisomerase I inhibition by camptothecin induces escape of RNA polymerase II from promoter-proximal pause site, antisense transcription and histone acetylation at the human HIF-1alpha gene locus.
Baranello L; Bertozzi D; Fogli MV; Pommier Y; Capranico G
Nucleic Acids Res; 2010 Jan; 38(1):159-71. PubMed ID: 19854946
[TBL] [Abstract][Full Text] [Related]
2. Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation.
Marinello J; Chillemi G; Bueno S; Manzo SG; Capranico G
Nucleic Acids Res; 2013 Dec; 41(22):10110-23. PubMed ID: 23999093
[TBL] [Abstract][Full Text] [Related]
3. Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cells.
Khobta A; Ferri F; Lotito L; Montecucco A; Rossi R; Capranico G
J Mol Biol; 2006 Mar; 357(1):127-38. PubMed ID: 16427078
[TBL] [Abstract][Full Text] [Related]
4. Dissecting the transcriptional functions of human DNA topoisomerase I by selective inhibitors: implications for physiological and therapeutic modulation of enzyme activity.
Capranico G; Marinello J; Baranello L
Biochim Biophys Acta; 2010 Dec; 1806(2):240-50. PubMed ID: 20600630
[TBL] [Abstract][Full Text] [Related]
5. Pausing sites of RNA polymerase II on actively transcribed genes are enriched in DNA double-stranded breaks.
Singh S; Szlachta K; Manukyan A; Raimer HM; Dinda M; Bekiranov S; Wang YH
J Biol Chem; 2020 Mar; 295(12):3990-4000. PubMed ID: 32029477
[TBL] [Abstract][Full Text] [Related]
6. The natural inhibitor of DNA topoisomerase I, camptothecin, modulates HIF-1α activity by changing miR expression patterns in human cancer cells.
Bertozzi D; Marinello J; Manzo SG; Fornari F; Gramantieri L; Capranico G
Mol Cancer Ther; 2014 Jan; 13(1):239-48. PubMed ID: 24252850
[TBL] [Abstract][Full Text] [Related]
7. SUV420H2-mediated H4K20 trimethylation enforces RNA polymerase II promoter-proximal pausing by blocking hMOF-dependent H4K16 acetylation.
Kapoor-Vazirani P; Kagey JD; Vertino PM
Mol Cell Biol; 2011 Apr; 31(8):1594-609. PubMed ID: 21321083
[TBL] [Abstract][Full Text] [Related]
8. Rhythmic binding of Topoisomerase I impacts on the transcription of Bmal1 and circadian period.
Onishi Y; Kawano Y
Nucleic Acids Res; 2012 Oct; 40(19):9482-92. PubMed ID: 22904072
[TBL] [Abstract][Full Text] [Related]
9. Genome-wide analysis of novel splice variants induced by topoisomerase I poisoning shows preferential occurrence in genes encoding splicing factors.
Solier S; Barb J; Zeeberg BR; Varma S; Ryan MC; Kohn KW; Weinstein JN; Munson PJ; Pommier Y
Cancer Res; 2010 Oct; 70(20):8055-65. PubMed ID: 20817775
[TBL] [Abstract][Full Text] [Related]
10. Characterization of novel antisense HIF-1α transcripts in human cancers.
Bertozzi D; Iurlaro R; Sordet O; Marinello J; Zaffaroni N; Capranico G
Cell Cycle; 2011 Sep; 10(18):3189-97. PubMed ID: 21897117
[TBL] [Abstract][Full Text] [Related]
11. Hyperphosphorylation of RNA polymerase II in response to topoisomerase I cleavage complexes and its association with transcription- and BRCA1-dependent degradation of topoisomerase I.
Sordet O; Larochelle S; Nicolas E; Stevens EV; Zhang C; Shokat KM; Fisher RP; Pommier Y
J Mol Biol; 2008 Sep; 381(3):540-9. PubMed ID: 18588899
[TBL] [Abstract][Full Text] [Related]
12. Copper affects the binding of HIF-1α to the critical motifs of its target genes.
Wu Z; Zhang W; Kang YJ
Metallomics; 2019 Feb; 11(2):429-438. PubMed ID: 30566157
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.
Lou JJ; Chua YL; Chew EH; Gao J; Bushell M; Hagen T
PLoS One; 2010 May; 5(5):e10522. PubMed ID: 20479887
[TBL] [Abstract][Full Text] [Related]
14. Elongation by RNA polymerase II on chromatin templates requires topoisomerase activity.
Mondal N; Zhang Y; Jonsson Z; Dhar SK; Kannapiran M; Parvin JD
Nucleic Acids Res; 2003 Sep; 31(17):5016-24. PubMed ID: 12930951
[TBL] [Abstract][Full Text] [Related]
15. RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.
Baranello L; Wojtowicz D; Cui K; Devaiah BN; Chung HJ; Chan-Salis KY; Guha R; Wilson K; Zhang X; Zhang H; Piotrowski J; Thomas CJ; Singer DS; Pugh BF; Pommier Y; Przytycka TM; Kouzine F; Lewis BA; Zhao K; Levens D
Cell; 2016 Apr; 165(2):357-71. PubMed ID: 27058666
[TBL] [Abstract][Full Text] [Related]
16. CBP Regulates Recruitment and Release of Promoter-Proximal RNA Polymerase II.
Boija A; Mahat DB; Zare A; Holmqvist PH; Philip P; Meyers DJ; Cole PA; Lis JT; Stenberg P; Mannervik M
Mol Cell; 2017 Nov; 68(3):491-503.e5. PubMed ID: 29056321
[TBL] [Abstract][Full Text] [Related]
17. Identification and characterization of a deletion mutant of DNA topoisomerase I mRNA in a camptothecin-resistant subline of human colon carcinoma.
Yanase K; Sugimoto Y; Tsukahara S; Oh-Hara T; Andoh T; Tsuruo T
Jpn J Cancer Res; 2000 May; 91(5):551-9. PubMed ID: 10835501
[TBL] [Abstract][Full Text] [Related]
18. In vivo sequencing of camptothecin-induced topoisomerase I cleavage sites in human colon carcinoma cells.
Pondarré C; Strumberg D; Fujimori A; Torres-León R; Pommier Y
Nucleic Acids Res; 1997 Oct; 25(20):4111-6. PubMed ID: 9321666
[TBL] [Abstract][Full Text] [Related]
19. A dual role for the histone methyltransferase PR-SET7/SETD8 and histone H4 lysine 20 monomethylation in the local regulation of RNA polymerase II pausing.
Kapoor-Vazirani P; Vertino PM
J Biol Chem; 2014 Mar; 289(11):7425-37. PubMed ID: 24459145
[TBL] [Abstract][Full Text] [Related]
20. Dynamic Effects of Topoisomerase I Inhibition on R-Loops and Short Transcripts at Active Promoters.
Marinello J; Bertoncini S; Aloisi I; Cristini A; Malagoli Tagliazucchi G; Forcato M; Sordet O; Capranico G
PLoS One; 2016; 11(1):e0147053. PubMed ID: 26784695
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]