BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 19856143)

  • 1. Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis.
    Reekmans SM; Pflanzner T; Gordts PL; Isbert S; Zimmermann P; Annaert W; Weggen S; Roebroek AJ; Pietrzik CU
    Cell Mol Life Sci; 2010 Jan; 67(1):135-45. PubMed ID: 19856143
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis.
    Gordts PL; Reekmans S; Lauwers A; Van Dongen A; Verbeek L; Roebroek AJ
    Arterioscler Thromb Vasc Biol; 2009 Sep; 29(9):1258-64. PubMed ID: 19667105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutant Lrp1 knock-in mice generated by recombinase-mediated cassette exchange reveal differential importance of the NPXY motifs in the intracellular domain of LRP1 for normal fetal development.
    Roebroek AJ; Reekmans S; Lauwers A; Feyaerts N; Smeijers L; Hartmann D
    Mol Cell Biol; 2006 Jan; 26(2):605-16. PubMed ID: 16382151
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype.
    Maier W; Bednorz M; Meister S; Roebroek A; Weggen S; Schmitt U; Pietrzik CU
    Mol Neurodegener; 2013 Jul; 8():25. PubMed ID: 23866919
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.
    Knisely JM; Li Y; Griffith JM; Geuze HJ; Schwartz AL; Bu G
    Exp Cell Res; 2007 Sep; 313(15):3298-307. PubMed ID: 17658514
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins.
    Fischer AW; Albers K; Krott LM; Hoffzimmer B; Heine M; Schmale H; Scheja L; Gordts PLSM; Heeren J
    Mol Metab; 2018 Oct; 16():88-99. PubMed ID: 30100244
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration.
    Rabiej VK; Pflanzner T; Wagner T; Goetze K; Storck SE; Eble JA; Weggen S; Mueller-Klieser W; Pietrzik CU
    Exp Cell Res; 2016 Jan; 340(1):102-15. PubMed ID: 26610862
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Convergent Signaling Pathways Controlled by LRP1 (Receptor-related Protein 1) Cytoplasmic and Extracellular Domains Limit Cellular Cholesterol Accumulation.
    El Asmar Z; Terrand J; Jenty M; Host L; Mlih M; Zerr A; Justiniano H; Matz RL; Boudier C; Scholler E; Garnier JM; Bertaccini D; Thiersé D; Schaeffer C; Van Dorsselaer A; Herz J; Bruban V; Boucher P
    J Biol Chem; 2016 Mar; 291(10):5116-27. PubMed ID: 26792864
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A sorting nexin 17-binding domain within the LRP1 cytoplasmic tail mediates receptor recycling through the basolateral sorting endosome.
    Farfán P; Lee J; Larios J; Sotelo P; Bu G; Marzolo MP
    Traffic; 2013 Jul; 14(7):823-38. PubMed ID: 23593972
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice.
    Gordts PL; Bartelt A; Nilsson SK; Annaert W; Christoffersen C; Nielsen LB; Heeren J; Roebroek AJ
    PLoS One; 2012; 7(6):e38330. PubMed ID: 22701627
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The YXXL motif, but not the two NPXY motifs, serves as the dominant endocytosis signal for low density lipoprotein receptor-related protein.
    Li Y; Marzolo MP; van Kerkhof P; Strous GJ; Bu G
    J Biol Chem; 2000 Jun; 275(22):17187-94. PubMed ID: 10747918
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
    Xian X; Ding Y; Dieckmann M; Zhou L; Plattner F; Liu M; Parks JS; Hammer RE; Boucher P; Tsai S; Herz J
    Elife; 2017 Nov; 6():. PubMed ID: 29144234
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.
    Guttman M; Betts GN; Barnes H; Ghassemian M; van der Geer P; Komives EA
    Proteomics; 2009 Nov; 9(22):5016-28. PubMed ID: 19771558
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Low density lipoprotein receptor-related protein 1 (LRP1) modulates N-methyl-D-aspartate (NMDA) receptor-dependent intracellular signaling and NMDA-induced regulation of postsynaptic protein complexes.
    Nakajima C; Kulik A; Frotscher M; Herz J; Schäfer M; Bock HH; May P
    J Biol Chem; 2013 Jul; 288(30):21909-23. PubMed ID: 23760271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation.
    Jaeschke A; Haller A; Cash JG; Nam C; Igel E; Roebroek AJM; Hui DY
    J Lipid Res; 2021; 62():100012. PubMed ID: 33500241
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural, biochemical and signaling properties of the low-density lipoprotein receptor gene family.
    Hussain MM
    Front Biosci; 2001 Mar; 6():D417-28. PubMed ID: 11229872
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.
    Betts GN; van der Geer P; Komives EA
    J Biol Chem; 2008 Jun; 283(23):15656-64. PubMed ID: 18381291
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The functional role of the second NPXY motif of the LRP1 beta-chain in tissue-type plasminogen activator-mediated activation of N-methyl-D-aspartate receptors.
    Martin AM; Kuhlmann C; Trossbach S; Jaeger S; Waldron E; Roebroek A; Luhmann HJ; Laatsch A; Weggen S; Lessmann V; Pietrzik CU
    J Biol Chem; 2008 May; 283(18):12004-13. PubMed ID: 18321860
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Low-density lipoprotein receptor-related protein 1 mediates hypoxia-induced very low density lipoprotein-cholesteryl ester uptake and accumulation in cardiomyocytes.
    Cal R; Castellano J; Revuelta-López E; Aledo R; Barriga M; Farré J; Vilahur G; Nasarre L; Hove-Madsen L; Badimon L; Llorente-Cortés V
    Cardiovasc Res; 2012 Jun; 94(3):469-79. PubMed ID: 22454363
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.
    Chen WJ; Goldstein JL; Brown MS
    J Biol Chem; 1990 Feb; 265(6):3116-23. PubMed ID: 1968060
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.