BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

229 related articles for article (PubMed ID: 19857576)

  • 1. Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity.
    Saul FA; Prijatelj-Znidarsic P; Vulliez-le Normand B; Villette B; Raynal B; Pungercar J; Krizaj I; Faure G
    J Struct Biol; 2010 Mar; 169(3):360-9. PubMed ID: 19857576
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystallographic characterization of functional sites of crotoxin and ammodytoxin, potent β-neurotoxins from Viperidae venom.
    Faure G; Saul F
    Toxicon; 2012 Sep; 60(4):531-8. PubMed ID: 22683534
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The C-terminal and beta-wing regions of ammodytoxin A, a neurotoxic phospholipase A2 from Vipera ammodytes ammodytes, are critical for binding to factor Xa and for anticoagulant effect.
    Prijatelj P; Charnay M; Ivanovski G; Jenko Z; Pungercar J; Krizaj I; Faure G
    Biochimie; 2006 Jan; 88(1):69-76. PubMed ID: 16039772
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mapping the structural determinants of presynaptic neurotoxicity of snake venom phospholipases A2.
    Prijatelj P; Jenko Praznikar Z; Petan T; Krizaj I; Pungercar J
    Toxicon; 2008 Jun; 51(8):1520-9. PubMed ID: 18513779
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of a novel binding site for calmodulin in ammodytoxin A, a neurotoxic group IIA phospholipase A2.
    Prijatelj P; Sribar J; Ivanovski G; Krizaj I; Gubensek F; Pungercar J
    Eur J Biochem; 2003 Jul; 270(14):3018-25. PubMed ID: 12846835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of a dimeric Ser49- PLA₂-like myotoxic component of the Vipera ammodytes meridionalis venomics reveals determinants of myotoxicity and membrane damaging activity.
    Georgieva D; Coronado M; Oberthür D; Buck F; Duhalov D; Arni RK; Betzel C
    Mol Biosyst; 2012 Apr; 8(5):1405-11. PubMed ID: 22362132
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The first phospholipase inhibitor from the serum of Vipera ammodytes ammodytes.
    Sribar J; Kovacic L; Draskovic P; Faure G; Krizaj I
    FEBS J; 2007 Dec; 274(23):6055-64. PubMed ID: 17970753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chip electrophoretic separation of highly homologous ammodytoxin isoforms: three neurotoxic phospholipases A2 of Vipera ammodytes ammodytes venom.
    Weiss VU; Reitschmidt S; Friesz V; Križaj I; Günter Allmaier ; Marchetti-Deschmann M
    Electrophoresis; 2014 Aug; 35(15):2137-45. PubMed ID: 24431226
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Comparative analysis of the venom proteomes of Vipera ammodytes ammodytes and Vipera ammodytes meridionalis.
    Georgieva D; Risch M; Kardas A; Buck F; von Bergen M; Betzel C
    J Proteome Res; 2008 Mar; 7(3):866-86. PubMed ID: 18257516
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An aromatic, but not a basic, residue is involved in the toxicity of group-II phospholipase A2 neurotoxins.
    Pungercar J; Krizaj I; Liang NS; Gubensek F
    Biochem J; 1999 Jul; 341 ( Pt 1)(Pt 1):139-45. PubMed ID: 10377255
    [TBL] [Abstract][Full Text] [Related]  

  • 11. cDNA cloning, structural, and functional analyses of venom phospholipases A₂ and a Kunitz-type protease inhibitor from steppe viper Vipera ursinii renardi.
    Tsai IH; Wang YM; Cheng AC; Starkov V; Osipov A; Nikitin I; Makarova Y; Ziganshin R; Utkin Y
    Toxicon; 2011 Feb; 57(2):332-41. PubMed ID: 21185324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutagenesis analyses explore residues responsible for the neurotoxic and anticoagulant activities of Trimucrotoxin, a pit-viper venom Asn6-phospholipase A2.
    Tsai IH; Wang YM; Hseu MJ
    Biochimie; 2011 Feb; 93(2):277-85. PubMed ID: 20920547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural basis of the significant calmodulin-induced increase in the enzymatic activity of secreted phospholipases A(2).
    Kovacic L; Novinec M; Petan T; Krizaj I
    Protein Eng Des Sel; 2010 Jun; 23(6):479-87. PubMed ID: 20348188
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Binding to the high-affinity M-type receptor for secreted phospholipases A(2) is not obligatory for the presynaptic neurotoxicity of ammodytoxin A.
    Prijatelj P; Vardjan N; Rowan EG; Krizaj I; Pungercar J
    Biochimie; 2006 Oct; 88(10):1425-33. PubMed ID: 16815622
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Toxicity evolution of Vipera aspis aspis venom: identification and molecular modeling of a novel phospholipase A(2) heterodimer neurotoxin.
    Jan V; Maroun RC; Robbe-Vincent A; De Haro L; Choumet V
    FEBS Lett; 2002 Sep; 527(1-3):263-8. PubMed ID: 12220671
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neurotoxic phospholipases A2 ammodytoxin and crotoxin bind to distinct high-affinity protein acceptors in Torpedo marmorata electric organ.
    Krizaj I; Faure G; Gubensek F; Bon C
    Biochemistry; 1997 Mar; 36(10):2779-87. PubMed ID: 9062105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a human coagulation factor Xa-binding site on Viperidae snake venom phospholipases A2 by affinity binding studies and molecular bioinformatics.
    Faure G; Gowda VT; Maroun RC
    BMC Struct Biol; 2007 Dec; 7():82. PubMed ID: 18062812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A recent evaluation of the lethal potencies of ammodytoxins.
    Prijatelj-Žnidaršič P; Pungerčar J
    Toxicon; 2012 May; 59(6):642-3. PubMed ID: 22406514
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein disulphide isomerase binds ammodytoxin strongly: possible implications for toxin trafficking.
    Sribar J; Anderluh G; Fox JW; Krizaj I
    Biochem Biophys Res Commun; 2005 Apr; 329(2):733-7. PubMed ID: 15737647
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural and Functional Characterization of Anticoagulant, FXa-binding Viperidae Snake Venom Phospholipases A2.
    Faure G; Saul F
    Acta Chim Slov; 2011 Dec; 58(4):671-7. PubMed ID: 24061114
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.