BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

552 related articles for article (PubMed ID: 19861159)

  • 1. Oxygen-sensing under the influence of nitric oxide.
    Berchner-Pfannschmidt U; Tug S; Kirsch M; Fandrey J
    Cell Signal; 2010 Mar; 22(3):349-56. PubMed ID: 19861159
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2.
    Berchner-Pfannschmidt U; Yamac H; Trinidad B; Fandrey J
    J Biol Chem; 2007 Jan; 282(3):1788-96. PubMed ID: 17060326
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Non-hypoxic activation of the negative regulatory feedback loop of prolyl-hydroxylase oxygen sensors.
    Tug S; Delos Reyes B; Fandrey J; Berchner-Pfannschmidt U
    Biochem Biophys Res Commun; 2009 Jul; 384(4):519-23. PubMed ID: 19427832
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.
    Callapina M; Zhou J; Schnitzer S; Metzen E; Lohr C; Deitmer JW; Brüne B
    Exp Cell Res; 2005 May; 306(1):274-84. PubMed ID: 15878351
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Intracellular localisation of human HIF-1 alpha hydroxylases: implications for oxygen sensing.
    Metzen E; Berchner-Pfannschmidt U; Stengel P; Marxsen JH; Stolze I; Klinger M; Huang WQ; Wotzlaw C; Hellwig-Bürgel T; Jelkmann W; Acker H; Fandrey J
    J Cell Sci; 2003 Apr; 116(Pt 7):1319-26. PubMed ID: 12615973
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor.
    Tarhonskaya H; Hardy AP; Howe EA; Loik ND; Kramer HB; McCullagh JS; Schofield CJ; Flashman E
    J Biol Chem; 2015 Aug; 290(32):19726-42. PubMed ID: 26112411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Peroxynitrite as an alternative donor of oxygen in HIF-1alpha proline hydroxylation under low oxygen availability.
    Sumbayev VV; Yasinska IM
    Free Radic Res; 2006 Jun; 40(6):631-5. PubMed ID: 16753841
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia-inducible factor 1 (HIF-1) pathway.
    Semenza GL
    Sci STKE; 2007 Oct; 2007(407):cm8. PubMed ID: 17925579
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NO restores HIF-1alpha hydroxylation during hypoxia: role of reactive oxygen species.
    Callapina M; Zhou J; Schmid T; Köhl R; Brüne B
    Free Radic Biol Med; 2005 Oct; 39(7):925-36. PubMed ID: 16140212
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases.
    Koivunen P; Hirsilä M; Günzler V; Kivirikko KI; Myllyharju J
    J Biol Chem; 2004 Mar; 279(11):9899-904. PubMed ID: 14701857
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.
    Kaelin WG; Ratcliffe PJ
    Mol Cell; 2008 May; 30(4):393-402. PubMed ID: 18498744
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prolyl hydroxylases 2 and 3 act in gliomas as protective negative feedback regulators of hypoxia-inducible factors.
    Henze AT; Riedel J; Diem T; Wenner J; Flamme I; Pouyseggur J; Plate KH; Acker T
    Cancer Res; 2010 Jan; 70(1):357-66. PubMed ID: 20028863
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nitric oxide produced endogenously is responsible for hypoxia-induced HIF-1α stabilization in colon carcinoma cells.
    Chowdhury R; Godoy LC; Thiantanawat A; Trudel LJ; Deen WM; Wogan GN
    Chem Res Toxicol; 2012 Oct; 25(10):2194-202. PubMed ID: 22971010
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected].
    Stolze IP; Tian YM; Appelhoff RJ; Turley H; Wykoff CC; Gleadle JM; Ratcliffe PJ
    J Biol Chem; 2004 Oct; 279(41):42719-25. PubMed ID: 15302861
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The zinc chelator, N,N,N',N'-tetrakis (2-pyridylmethyl) ethylenediamine, increases the level of nonfunctional HIF-1alpha protein in normoxic cells.
    Choi SM; Choi KO; Lee N; Oh M; Park H
    Biochem Biophys Res Commun; 2006 May; 343(4):1002-8. PubMed ID: 16579968
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nitric oxide impairs normoxic degradation of HIF-1alpha by inhibition of prolyl hydroxylases.
    Metzen E; Zhou J; Jelkmann W; Fandrey J; Brüne B
    Mol Biol Cell; 2003 Aug; 14(8):3470-81. PubMed ID: 12925778
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms.
    Martín-Puig S; Temes E; Olmos G; Jones DR; Aragonés J; Landázuri MO
    J Biol Chem; 2004 Mar; 279(10):9504-11. PubMed ID: 14681229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression of prolyl-hydroxylases PHD-1, 2 and 3 and of the asparagine hydroxylase FIH in non-small cell lung cancer relates to an activated HIF pathway.
    Giatromanolaki A; Koukourakis MI; Pezzella F; Turley H; Sivridis E; Bouros D; Bougioukas G; Harris AL; Gatter KC
    Cancer Lett; 2008 Apr; 262(1):87-93. PubMed ID: 18187257
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases.
    Chan MC; Ilott NE; Schödel J; Sims D; Tumber A; Lippl K; Mole DR; Pugh CW; Ratcliffe PJ; Ponting CP; Schofield CJ
    J Biol Chem; 2016 Sep; 291(39):20661-73. PubMed ID: 27502280
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.