These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

590 related articles for article (PubMed ID: 19864431)

  • 1. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
    Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
    J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
    Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
    J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Receptor-recognized α₂-macroglobulin binds to cell surface-associated GRP78 and activates mTORC1 and mTORC2 signaling in prostate cancer cells.
    Misra UK; Pizzo SV
    PLoS One; 2012; 7(12):e51735. PubMed ID: 23272152
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The proline-rich Akt substrate of 40 kDa (PRAS40) is a physiological substrate of mammalian target of rapamycin complex 1.
    Oshiro N; Takahashi R; Yoshino K; Tanimura K; Nakashima A; Eguchi S; Miyamoto T; Hara K; Takehana K; Avruch J; Kikkawa U; Yonezawa K
    J Biol Chem; 2007 Jul; 282(28):20329-39. PubMed ID: 17517883
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Specific activation of mTORC1 by Rheb G-protein in vitro involves enhanced recruitment of its substrate protein.
    Sato T; Nakashima A; Guo L; Tamanoi F
    J Biol Chem; 2009 May; 284(19):12783-91. PubMed ID: 19299511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation.
    Carrière A; Cargnello M; Julien LA; Gao H; Bonneil E; Thibault P; Roux PP
    Curr Biol; 2008 Sep; 18(17):1269-77. PubMed ID: 18722121
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Raptor and Rheb negatively regulate skeletal myogenesis through suppression of insulin receptor substrate 1 (IRS1).
    Ge Y; Yoon MS; Chen J
    J Biol Chem; 2011 Oct; 286(41):35675-35682. PubMed ID: 21852229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alkaline intracellular pH (pHi) increases PI3K activity to promote mTORC1 and mTORC2 signaling and function during growth factor limitation.
    Kazyken D; Lentz SI; Wadley M; Fingar DC
    J Biol Chem; 2023 Sep; 299(9):105097. PubMed ID: 37507012
    [TBL] [Abstract][Full Text] [Related]  

  • 10. cAMP inhibits mammalian target of rapamycin complex-1 and -2 (mTORC1 and 2) by promoting complex dissociation and inhibiting mTOR kinase activity.
    Xie J; Ponuwei GA; Moore CE; Willars GB; Tee AR; Herbert TP
    Cell Signal; 2011 Dec; 23(12):1927-35. PubMed ID: 21763421
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Amino acid regulation of TOR complex 1.
    Avruch J; Long X; Ortiz-Vega S; Rapley J; Papageorgiou A; Dai N
    Am J Physiol Endocrinol Metab; 2009 Apr; 296(4):E592-602. PubMed ID: 18765678
    [TBL] [Abstract][Full Text] [Related]  

  • 12. ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1).
    Carriere A; Romeo Y; Acosta-Jaquez HA; Moreau J; Bonneil E; Thibault P; Fingar DC; Roux PP
    J Biol Chem; 2011 Jan; 286(1):567-77. PubMed ID: 21071439
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA; Keller JA; Foster KG; Ekim B; Soliman GA; Feener EP; Ballif BA; Fingar DC
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.
    Sancak Y; Peterson TR; Shaul YD; Lindquist RA; Thoreen CC; Bar-Peled L; Sabatini DM
    Science; 2008 Jun; 320(5882):1496-501. PubMed ID: 18497260
    [TBL] [Abstract][Full Text] [Related]  

  • 15. mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.
    Harwood FC; Shu L; Houghton PJ
    J Biol Chem; 2008 Feb; 283(5):2575-85. PubMed ID: 18056704
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation.
    Ramírez-Valle F; Badura ML; Braunstein S; Narasimhan M; Schneider RJ
    Mol Cell Biol; 2010 Jul; 30(13):3151-64. PubMed ID: 20439490
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation of Raptor by p38beta participates in arsenite-induced mammalian target of rapamycin complex 1 (mTORC1) activation.
    Wu XN; Wang XK; Wu SQ; Lu J; Zheng M; Wang YH; Zhou H; Zhang H; Han J
    J Biol Chem; 2011 Sep; 286(36):31501-11. PubMed ID: 21757713
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
    Wang L; Harris TE; Lawrence JC
    J Biol Chem; 2008 Jun; 283(23):15619-27. PubMed ID: 18372248
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb.
    Tee AR; Manning BD; Roux PP; Cantley LC; Blenis J
    Curr Biol; 2003 Aug; 13(15):1259-68. PubMed ID: 12906785
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Raptor binds the SAIN (Shc and IRS-1 NPXY binding) domain of insulin receptor substrate-1 (IRS-1) and regulates the phosphorylation of IRS-1 at Ser-636/639 by mTOR.
    Tzatsos A
    J Biol Chem; 2009 Aug; 284(34):22525-34. PubMed ID: 19561084
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 30.