BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

192 related articles for article (PubMed ID: 19875454)

  • 1. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells.
    Mitrofan LM; Castells FB; Pelkonen J; Mönkkönen J
    J Biol Chem; 2010 Jan; 285(3):1967-79. PubMed ID: 19875454
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The level of ATP analog and isopentenyl pyrophosphate correlates with zoledronic acid-induced apoptosis in cancer cells in vitro.
    Mitrofan LM; Pelkonen J; Mönkkönen J
    Bone; 2009 Dec; 45(6):1153-60. PubMed ID: 19699819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells.
    Räikkönen J; Mönkkönen H; Auriola S; Mönkkönen J
    Biochem Pharmacol; 2010 Mar; 79(5):777-83. PubMed ID: 19819230
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Zoledronic acid induces formation of a pro-apoptotic ATP analogue and isopentenyl pyrophosphate in osteoclasts in vivo and in MCF-7 cells in vitro.
    Räikkönen J; Crockett JC; Rogers MJ; Mönkkönen H; Auriola S; Mönkkönen J
    Br J Pharmacol; 2009 Jun; 157(3):427-35. PubMed ID: 19371349
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bisphosphonate-induced ATP analog formation and its effect on inhibition of cancer cell growth.
    Mönkkönen H; Kuokkanen J; Holen I; Evans A; Lefley DV; Jauhiainen M; Auriola S; Mönkkönen J
    Anticancer Drugs; 2008 Apr; 19(4):391-9. PubMed ID: 18454049
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High phosphoantigen levels in bisphosphonate-treated human breast tumors promote Vgamma9Vdelta2 T-cell chemotaxis and cytotoxicity in vivo.
    Benzaïd I; Mönkkönen H; Stresing V; Bonnelye E; Green J; Mönkkönen J; Touraine JL; Clézardin P
    Cancer Res; 2011 Jul; 71(13):4562-72. PubMed ID: 21646473
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Zoledronic acid-induced IPP/ApppI production in vivo.
    Mönkkönen H; Ottewell PD; Kuokkanen J; Mönkkönen J; Auriola S; Holen I
    Life Sci; 2007 Sep; 81(13):1066-70. PubMed ID: 17850825
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nitrogen containing bisphosphonates induce apoptosis and inhibit the mevalonate pathway, impairing Ras membrane localization in prostate cancer cells.
    Oades GM; Senaratne SG; Clarke IA; Kirby RS; Colston KW
    J Urol; 2003 Jul; 170(1):246-52. PubMed ID: 12796698
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.
    Bruzzese F; Pucci B; Milone MR; Ciardiello C; Franco R; Chianese MI; Rocco M; Di Gennaro E; Leone A; Luciano A; Arra C; Santini D; Caraglia M; Budillon A
    Cell Death Dis; 2013 Oct; 4(10):e878. PubMed ID: 24157872
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates.
    Mönkkönen H; Auriola S; Lehenkari P; Kellinsalmi M; Hassinen IE; Vepsäläinen J; Mönkkönen J
    Br J Pharmacol; 2006 Feb; 147(4):437-45. PubMed ID: 16402039
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Comparison of γδ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid.
    Idrees AS; Sugie T; Inoue C; Murata-Hirai K; Okamura H; Morita CT; Minato N; Toi M; Tanaka Y
    Cancer Sci; 2013 May; 104(5):536-42. PubMed ID: 23387443
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Zoledronic acid produces antitumor effects on mesothelioma through apoptosis and S-phase arrest in p53-independent and Ras prenylation-independent manners.
    Okamoto S; Kawamura K; Li Q; Yamanaka M; Yang S; Fukamachi T; Tada Y; Tatsumi K; Shimada H; Hiroshima K; Kobayashi H; Tagawa M
    J Thorac Oncol; 2012 May; 7(5):873-82. PubMed ID: 22481236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic activity of the histone deacetylase inhibitor suberoylanilide hydroxamic acid and the bisphosphonate zoledronic acid against prostate cancer cells in vitro.
    Sonnemann J; Bumbul B; Beck JF
    Mol Cancer Ther; 2007 Nov; 6(11):2976-84. PubMed ID: 18025282
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry.
    Jauhiainen M; Mönkkönen H; Räikkönen J; Mönkkönen J; Auriola S
    J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Oct; 877(27):2967-75. PubMed ID: 19665949
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of bisphosphonate zoledronic acid in hepatocellular carcinoma, depending on mevalonate pathway.
    Honda Y; Takahashi S; Zhang Y; Ono A; Murakami E; Shi N; Kawaoka T; Miki D; Tsuge M; Hiraga N; Abe H; Ochi H; Imamura M; Aikata H; Chayama K
    J Gastroenterol Hepatol; 2015 Mar; 30(3):619-27. PubMed ID: 25167891
    [TBL] [Abstract][Full Text] [Related]  

  • 16. R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation.
    Caraglia M; Marra M; Leonetti C; Meo G; D'Alessandro AM; Baldi A; Santini D; Tonini G; Bertieri R; Zupi G; Budillon A; Abbruzzese A
    J Cell Physiol; 2007 May; 211(2):533-43. PubMed ID: 17192846
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells.
    Ebert R; Meissner-Weigl J; Zeck S; Määttä J; Auriola S; Coimbra de Sousa S; Mentrup B; Graser S; Rachner TD; Hofbauer LC; Jakob F
    Mol Cancer; 2014 Dec; 13():265. PubMed ID: 25496233
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of cell death of human osteogenic sarcoma cells by zoledronic acid resembles anoikis.
    Evdokiou A; Labrinidis A; Bouralexis S; Hay S; Findlay DM
    Bone; 2003 Aug; 33(2):216-28. PubMed ID: 14499355
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic Anticancer Action of Lysosomal Membrane Permeabilization and Glycolysis Inhibition.
    Kosic M; Arsikin-Csordas K; Paunovic V; Firestone RA; Ristic B; Mircic A; Petricevic S; Bosnjak M; Zogovic N; Mandic M; Bumbasirevic V; Trajkovic V; Harhaji-Trajkovic L
    J Biol Chem; 2016 Oct; 291(44):22936-22948. PubMed ID: 27587392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferase.
    Fukai J; Koizumi F; Nakao N
    PLoS One; 2014; 9(8):e104538. PubMed ID: 25111384
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.