These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 19876913)

  • 41. The phosphoinositide 3-kinase pathway.
    Cantley LC
    Science; 2002 May; 296(5573):1655-7. PubMed ID: 12040186
    [TBL] [Abstract][Full Text] [Related]  

  • 42. A collagen-related peptide regulates phospholipase Cgamma2 via phosphatidylinositol 3-kinase in human platelets.
    Pasquet JM; Bobe R; Gross B; Gratacap MP; Tomlinson MG; Payrastre B; Watson SP
    Biochem J; 1999 Aug; 342 ( Pt 1)(Pt 1):171-7. PubMed ID: 10432314
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Ret oncogene signal transduction via a IRS-2/PI 3-kinase/PKB and a SHC/Grb-2 dependent pathway: possible implication for transforming activity in NIH3T3 cells.
    Hennige AM; Lammers R; Arlt D; Höppner W; Strack V; Niederfellner G; Seif FJ; Häring HU; Kellerer M
    Mol Cell Endocrinol; 2000 Sep; 167(1-2):69-76. PubMed ID: 11000521
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Nuclear phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3-kinase, Akt, and PTen: emerging key regulators of anti-apoptotic signaling and carcinogenesis.
    Martelli AM; Cocco L; Capitani S; Miscia S; Papa S; Manzoli FA
    Eur J Histochem; 2007; 51 Suppl 1():125-31. PubMed ID: 17703603
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is not mediated by oncogenic PIK3CA and AKT1 hotspot mutations.
    Hafner C; Landthaler M; Vogt T
    Exp Dermatol; 2010 Aug; 19(8):e222-7. PubMed ID: 20557351
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Specific gene expression signatures induced by the multiple oncogenic alterations that occur within the PTEN/PI3K/AKT pathway in lung cancer.
    De Marco C; Laudanna C; Rinaldo N; Oliveira DM; Ravo M; Weisz A; Ceccarelli M; Caira E; Rizzuto A; Zoppoli P; Malanga D; Viglietto G
    PLoS One; 2017; 12(6):e0178865. PubMed ID: 28662101
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Binding of phosphatidylinositol 3,4,5-trisphosphate to the pleckstrin homology domain of protein kinase B induces a conformational change.
    Milburn CC; Deak M; Kelly SM; Price NC; Alessi DR; Van Aalten DM
    Biochem J; 2003 Nov; 375(Pt 3):531-8. PubMed ID: 12964941
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Oncogenic E17K mutation in the pleckstrin homology domain of AKT1 promotes v-Abl-mediated pre-B-cell transformation and survival of Pim-deficient cells.
    Guo G; Qiu X; Wang S; Chen Y; Rothman PB; Wang Z; Chen Y; Wang G; Chen JL
    Oncogene; 2010 Jul; 29(26):3845-53. PubMed ID: 20440266
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.
    Russo C; Gao Y; Mancini P; Vanni C; Porotto M; Falasca M; Torrisi MR; Zheng Y; Eva A
    J Biol Chem; 2001 Jun; 276(22):19524-31. PubMed ID: 11278560
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Phosphatidylinositol 3-kinase-Akt signaling in pulmonary carcinoid cells.
    Pitt SC; Chen H; Kunnimalaiyaan M
    J Am Coll Surg; 2009 Jul; 209(1):82-8. PubMed ID: 19651067
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Activation of multiple signaling pathways is critical for fibroblast growth factor 2- and vascular endothelial growth factor-stimulated ovine fetoplacental endothelial cell proliferation.
    Zheng J; Wen Y; Song Y; Wang K; Chen DB; Magness RR
    Biol Reprod; 2008 Jan; 78(1):143-50. PubMed ID: 17901071
    [TBL] [Abstract][Full Text] [Related]  

  • 52. WJD008, a dual phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin inhibitor, prevents PI3K signaling and inhibits the proliferation of transformed cells with oncogenic PI3K mutant.
    Li T; Wang J; Wang X; Yang N; Chen SM; Tong LJ; Yang CH; Meng LH; Ding J
    J Pharmacol Exp Ther; 2010 Sep; 334(3):830-8. PubMed ID: 20522531
    [TBL] [Abstract][Full Text] [Related]  

  • 53. High-resolution structure of the pleckstrin homology domain of protein kinase b/akt bound to phosphatidylinositol (3,4,5)-trisphosphate.
    Thomas CC; Deak M; Alessi DR; van Aalten DM
    Curr Biol; 2002 Jul; 12(14):1256-62. PubMed ID: 12176338
    [TBL] [Abstract][Full Text] [Related]  

  • 54. The phosphatidylinositol (PI)-5-phosphate 4-kinase type II enzyme controls insulin signaling by regulating PI-3,4,5-trisphosphate degradation.
    Carricaburu V; Lamia KA; Lo E; Favereaux L; Payrastre B; Cantley LC; Rameh LE
    Proc Natl Acad Sci U S A; 2003 Aug; 100(17):9867-72. PubMed ID: 12897244
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Phosphoinositide 3-kinase targeting by the beta galactoside binding protein cytokine negates akt gene expression and leads aggressive breast cancer cells to apoptotic death.
    Wells V; Mallucci L
    Breast Cancer Res; 2009; 11(1):R2. PubMed ID: 19133120
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Rare cancer-specific mutations in PIK3CA show gain of function.
    Gymnopoulos M; Elsliger MA; Vogt PK
    Proc Natl Acad Sci U S A; 2007 Mar; 104(13):5569-74. PubMed ID: 17376864
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase.
    Didichenko SA; Tilton B; Hemmings BA; Ballmer-Hofer K; Thelen M
    Curr Biol; 1996 Oct; 6(10):1271-8. PubMed ID: 8939574
    [TBL] [Abstract][Full Text] [Related]  

  • 58. NEDD4-induced degradative ubiquitination of phosphatidylinositol 4-phosphate 5-kinase α and its implication in breast cancer cell proliferation.
    Tran MH; Seo E; Min S; Nguyen QT; Choi J; Lee UJ; Hong SS; Kang H; Mansukhani A; Jou I; Lee SY
    J Cell Mol Med; 2018 Sep; 22(9):4117-4129. PubMed ID: 29851245
    [TBL] [Abstract][Full Text] [Related]  

  • 59. A small molecule inhibits Akt through direct binding to Akt and preventing Akt membrane translocation.
    Kim D; Sun M; He L; Zhou QH; Chen J; Sun XM; Bepler G; Sebti SM; Cheng JQ
    J Biol Chem; 2010 Mar; 285(11):8383-94. PubMed ID: 20068047
    [TBL] [Abstract][Full Text] [Related]  

  • 60. PIP3-binding proteins promote age-dependent protein aggregation and limit survival in C. elegans.
    Ayyadevara S; Balasubramaniam M; Johnson J; Alla R; Mackintosh SG; Shmookler Reis RJ
    Oncotarget; 2016 Aug; 7(31):48870-48886. PubMed ID: 27429199
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.