BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 19883114)

  • 1. Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by human alkyladenine DNA glycosylase.
    Wolfe AE; O'Brien PJ
    Biochemistry; 2009 Dec; 48(48):11357-69. PubMed ID: 19883114
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by AlkA.
    Taylor EL; O'Brien PJ
    Biochemistry; 2015 Jan; 54(3):898-908. PubMed ID: 25537480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase.
    Hendershot JM; Wolfe AE; O'Brien PJ
    Biochemistry; 2011 Mar; 50(11):1864-74. PubMed ID: 21244040
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Search for DNA damage by human alkyladenine DNA glycosylase involves early intercalation by an aromatic residue.
    Hendershot JM; O'Brien PJ
    J Biol Chem; 2017 Sep; 292(39):16070-16080. PubMed ID: 28747435
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modeling the chemical step utilized by human alkyladenine DNA glycosylase: a concerted mechanism AIDS in selectively excising damaged purines.
    Rutledge LR; Wetmore SD
    J Am Chem Soc; 2011 Oct; 133(40):16258-69. PubMed ID: 21877721
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The formation of catalytically competent enzyme-substrate complex is not a bottleneck in lesion excision by human alkyladenine DNA glycosylase.
    Kuznetsov NA; Kiryutin AS; Kuznetsova AA; Panov MS; Barsukova MO; Yurkovskaya AV; Fedorova OS
    J Biomol Struct Dyn; 2017 Apr; 35(5):950-967. PubMed ID: 27025273
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-glycosyl bond formation catalyzed by human alkyladenine DNA glycosylase.
    Admiraal SJ; O'Brien PJ
    Biochemistry; 2010 Oct; 49(42):9024-6. PubMed ID: 20873830
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Investigation of the Flipping Dynamics of 1, N6-Ethenoadenine in Alkyladenine DNA Glycosylase.
    Liu B; Qi Y; Wang X; Gao X; Yao Y; Zhang L
    J Phys Chem B; 2024 Feb; 128(7):1606-1617. PubMed ID: 38331753
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG).
    Lee CY; Delaney JC; Kartalou M; Lingaraju GM; Maor-Shoshani A; Essigmann JM; Samson LD
    Biochemistry; 2009 Mar; 48(9):1850-61. PubMed ID: 19219989
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Base excision and DNA binding activities of human alkyladenine DNA glycosylase are sensitive to the base paired with a lesion.
    Abner CW; Lau AY; Ellenberger T; Bloom LB
    J Biol Chem; 2001 Apr; 276(16):13379-87. PubMed ID: 11278716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic mechanism of damage site recognition and uracil flipping by Escherichia coli uracil DNA glycosylase.
    Stivers JT; Pankiewicz KW; Watanabe KA
    Biochemistry; 1999 Jan; 38(3):952-63. PubMed ID: 9893991
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase.
    O'Brien PJ; Ellenberger T
    J Biol Chem; 2004 Mar; 279(11):9750-7. PubMed ID: 14688248
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Global Repair Profile of Human Alkyladenine DNA Glycosylase on Nucleosomes Reveals DNA Packaging Effects.
    Kennedy EE; Li C; Delaney S
    ACS Chem Biol; 2019 Aug; 14(8):1687-1692. PubMed ID: 31310499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines.
    O'Brien PJ; Ellenberger T
    Biochemistry; 2003 Oct; 42(42):12418-29. PubMed ID: 14567703
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site.
    O'Brien PJ; Ellenberger T
    J Biol Chem; 2004 Jun; 279(26):26876-84. PubMed ID: 15126496
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Critical role of DNA intercalation in enzyme-catalyzed nucleotide flipping.
    Hendershot JM; O'Brien PJ
    Nucleic Acids Res; 2014 Nov; 42(20):12681-90. PubMed ID: 25324304
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Comparison of the Base Excision and Direct Reversal Repair Pathways for Correcting 1,
    Caffrey PJ; Kher R; Bian K; Li D; Delaney S
    Chem Res Toxicol; 2020 Jul; 33(7):1888-1896. PubMed ID: 32293880
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The origins of high-affinity enzyme binding to an extrahelical DNA base.
    Krosky DJ; Song F; Stivers JT
    Biochemistry; 2005 Apr; 44(16):5949-59. PubMed ID: 15835884
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Promiscuous DNA alkyladenine glycosylase dramatically favors a bound lesion over undamaged adenine.
    Alexandrova AN
    Biophys Chem; 2010 Nov; 152(1-3):118-27. PubMed ID: 20840885
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.
    Prorok P; Saint-Pierre C; Gasparutto D; Fedorova OS; Ishchenko AA; Leh H; Buckle M; Tudek B; Saparbaev M
    PLoS One; 2012; 7(12):e51776. PubMed ID: 23251620
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.