These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 19884324)

  • 1. Human cytochrome P450 oxidoreductase deficiency caused by the Y181D mutation: molecular consequences and rescue of defect.
    Marohnic CC; Panda SP; McCammon K; Rueff J; Masters BS; Kranendonk M
    Drug Metab Dispos; 2010 Feb; 38(2):332-40. PubMed ID: 19884324
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency.
    Jin Y; Chen M; Penning TM; Miller WL
    Biochem J; 2015 May; 468(1):25-31. PubMed ID: 25728647
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutations of human cytochrome P450 reductase differentially modulate heme oxygenase-1 activity and oligomerization.
    Marohnic CC; Huber Iii WJ; Patrick Connick J; Reed JR; McCammon K; Panda SP; Martásek P; Backes WL; Masters BS
    Arch Biochem Biophys; 2011 Sep; 513(1):42-50. PubMed ID: 21741353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase.
    Kranendonk M; Marohnic CC; Panda SP; Duarte MP; Oliveira JS; Masters BS; Rueff J
    Arch Biochem Biophys; 2008 Jul; 475(2):93-9. PubMed ID: 18455494
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Clinical, structural and functional implications of mutations and polymorphisms in human NADPH P450 oxidoreductase.
    Flück CE; Nicolo C; Pandey AV
    Fundam Clin Pharmacol; 2007 Aug; 21(4):399-410. PubMed ID: 17635179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
    Xia C; Rwere F; Im S; Shen AL; Waskell L; Kim JP
    Biochemistry; 2018 Feb; 57(6):945-962. PubMed ID: 29308883
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Diminished FAD binding in the Y459H and V492E Antley-Bixler syndrome mutants of human cytochrome P450 reductase.
    Marohnic CC; Panda SP; Martásek P; Masters BS
    J Biol Chem; 2006 Nov; 281(47):35975-82. PubMed ID: 16998238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity.
    Rwere F; Cartee NMP; Yang Y; Waskell L
    J Inorg Biochem; 2024 Oct; 259():112667. PubMed ID: 39032346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Determination of the redox properties of human NADPH-cytochrome P450 reductase.
    Munro AW; Noble MA; Robledo L; Daff SN; Chapman SK
    Biochemistry; 2001 Feb; 40(7):1956-63. PubMed ID: 11329262
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Preparation and characterization of a 5'-deazaFAD T491V NADPH-cytochrome P450 reductase.
    Zhang H; Gruenke L; Saribas AS; Im SC; Shen AL; Kasper CB; Waskell L
    Biochemistry; 2003 Jun; 42(22):6804-13. PubMed ID: 12779335
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The flavoprotein domain of P450BM-3: expression, purification, and properties of the flavin adenine dinucleotide- and flavin mononucleotide-binding subdomains.
    Sevrioukova I; Truan G; Peterson JA
    Biochemistry; 1996 Jun; 35(23):7528-35. PubMed ID: 8652532
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
    Roitel O; Scrutton NS; Munro AW
    Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conformational changes of NADPH-cytochrome P450 oxidoreductase are essential for catalysis and cofactor binding.
    Xia C; Hamdane D; Shen AL; Choi V; Kasper CB; Pearl NM; Zhang H; Im SC; Waskell L; Kim JJ
    J Biol Chem; 2011 May; 286(18):16246-60. PubMed ID: 21345800
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural analysis of the FMN binding domain of NADPH-cytochrome P-450 oxidoreductase by site-directed mutagenesis.
    Shen AL; Porter TD; Wilson TE; Kasper CB
    J Biol Chem; 1989 May; 264(13):7584-9. PubMed ID: 2708380
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The FMN "140s Loop" of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450.
    Rwere F; Im S; Waskell L
    Int J Mol Sci; 2021 Sep; 22(19):. PubMed ID: 34638963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relaxation kinetics of cytochrome P450 reductase: internal electron transfer is limited by conformational change and regulated by coenzyme binding.
    Gutierrez A; Paine M; Wolf CR; Scrutton NS; Roberts GC
    Biochemistry; 2002 Apr; 41(14):4626-37. PubMed ID: 11926825
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The FMN-binding domain of cytochrome P450BM-3: resolution, reconstitution, and flavin analogue substitution.
    Haines DC; Sevrioukova IF; Peterson JA
    Biochemistry; 2000 Aug; 39(31):9419-29. PubMed ID: 10924137
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Differential contributions of NADPH-cytochrome P450 oxidoreductase FAD binding site residues to flavin binding and catalysis.
    Shen AL; Kasper CB
    J Biol Chem; 2000 Dec; 275(52):41087-91. PubMed ID: 11022049
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutants of Cytochrome P450 Reductase Lacking Either Gly-141 or Gly-143 Destabilize Its FMN Semiquinone.
    Rwere F; Xia C; Im S; Haque MM; Stuehr DJ; Waskell L; Kim JJ
    J Biol Chem; 2016 Jul; 291(28):14639-61. PubMed ID: 27189945
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Separate roles for FMN and FAD in catalysis by liver microsomal NADPH-cytochrome P-450 reductase.
    Vermilion JL; Ballou DP; Massey V; Coon MJ
    J Biol Chem; 1981 Jan; 256(1):266-77. PubMed ID: 6778861
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.