437 related articles for article (PubMed ID: 19884502)
1. Cyclodextrin overcomes deficient lysosome-to-endoplasmic reticulum transport of cholesterol in Niemann-Pick type C cells.
Abi-Mosleh L; Infante RE; Radhakrishnan A; Goldstein JL; Brown MS
Proc Natl Acad Sci U S A; 2009 Nov; 106(46):19316-21. PubMed ID: 19884502
[TBL] [Abstract][Full Text] [Related]
2. Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.
Goldman SD; Krise JP
J Biol Chem; 2010 Feb; 285(7):4983-94. PubMed ID: 20007703
[TBL] [Abstract][Full Text] [Related]
3. Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells.
Rosenbaum AI; Zhang G; Warren JD; Maxfield FR
Proc Natl Acad Sci U S A; 2010 Mar; 107(12):5477-82. PubMed ID: 20212119
[TBL] [Abstract][Full Text] [Related]
4. Physiological and coordinate downregulation of the NPC1 and NPC2 genes are associated with the sequestration of LDL-derived cholesterol within endocytic compartments.
Jelinek D; Patrick SM; Kitt KN; Chan T; Francis GA; Garver WS
J Cell Biochem; 2009 Dec; 108(5):1102-16. PubMed ID: 19746448
[TBL] [Abstract][Full Text] [Related]
5. Adenovirus RIDα uncovers a novel pathway requiring ORP1L for lipid droplet formation independent of NPC1.
Cianciola NL; Greene DJ; Morton RE; Carlin CR
Mol Biol Cell; 2013 Nov; 24(21):3309-25. PubMed ID: 24025716
[TBL] [Abstract][Full Text] [Related]
6. Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin.
Vance JE; Karten B
J Lipid Res; 2014 Aug; 55(8):1609-21. PubMed ID: 24664998
[TBL] [Abstract][Full Text] [Related]
7. NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
Frolov A; Zielinski SE; Crowley JR; Dudley-Rucker N; Schaffer JE; Ory DS
J Biol Chem; 2003 Jul; 278(28):25517-25. PubMed ID: 12719428
[TBL] [Abstract][Full Text] [Related]
8. ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.
Boadu E; Nelson RC; Francis GA
Biochim Biophys Acta; 2012 Mar; 1821(3):396-404. PubMed ID: 22179027
[TBL] [Abstract][Full Text] [Related]
9. Niemann-Pick type C 1 function requires lumenal domain residues that mediate cholesterol-dependent NPC2 binding.
Deffieu MS; Pfeffer SR
Proc Natl Acad Sci U S A; 2011 Nov; 108(47):18932-6. PubMed ID: 22065762
[TBL] [Abstract][Full Text] [Related]
10. β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease.
Tamura A; Yui N
J Biol Chem; 2015 Apr; 290(15):9442-54. PubMed ID: 25713067
[TBL] [Abstract][Full Text] [Related]
11. 2-Hydroxypropyl-gamma-cyclodextrin overcomes NPC1 deficiency by enhancing lysosome-ER association and autophagy.
Singhal A; Krystofiak ES; Jerome WG; Song B
Sci Rep; 2020 May; 10(1):8663. PubMed ID: 32457374
[TBL] [Abstract][Full Text] [Related]
12. NPC intracellular cholesterol transporter 1 (NPC1)-mediated cholesterol export from lysosomes.
Pfeffer SR
J Biol Chem; 2019 Feb; 294(5):1706-1709. PubMed ID: 30710017
[TBL] [Abstract][Full Text] [Related]
13. Function of the Niemann-Pick type C proteins and their bypass by cyclodextrin.
Vance JE; Peake KB
Curr Opin Lipidol; 2011 Jun; 22(3):204-9. PubMed ID: 21412152
[TBL] [Abstract][Full Text] [Related]
14. NPC2 facilitates bidirectional transfer of cholesterol between NPC1 and lipid bilayers, a step in cholesterol egress from lysosomes.
Infante RE; Wang ML; Radhakrishnan A; Kwon HJ; Brown MS; Goldstein JL
Proc Natl Acad Sci U S A; 2008 Oct; 105(40):15287-92. PubMed ID: 18772377
[TBL] [Abstract][Full Text] [Related]
15. Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice.
Peake KB; Vance JE
J Biol Chem; 2012 Mar; 287(12):9290-8. PubMed ID: 22277650
[TBL] [Abstract][Full Text] [Related]
16. Identification of surface residues on Niemann-Pick C2 essential for hydrophobic handoff of cholesterol to NPC1 in lysosomes.
Wang ML; Motamed M; Infante RE; Abi-Mosleh L; Kwon HJ; Brown MS; Goldstein JL
Cell Metab; 2010 Aug; 12(2):166-73. PubMed ID: 20674861
[TBL] [Abstract][Full Text] [Related]
17. Altered vitamin E status in Niemann-Pick type C disease.
Ulatowski L; Parker R; Davidson C; Yanjanin N; Kelley TJ; Corey D; Atkinson J; Porter F; Arai H; Walkley SU; Manor D
J Lipid Res; 2011 Jul; 52(7):1400-10. PubMed ID: 21550990
[TBL] [Abstract][Full Text] [Related]
18. Abnormal accumulation and recycling of glycoproteins visualized in Niemann-Pick type C cells using the chemical reporter strategy.
Mbua NE; Flanagan-Steet H; Johnson S; Wolfert MA; Boons GJ; Steet R
Proc Natl Acad Sci U S A; 2013 Jun; 110(25):10207-12. PubMed ID: 23733943
[TBL] [Abstract][Full Text] [Related]
19. Different kinetics of cholesterol delivery to components of the cholesterol homeostatic machinery: implications for cholesterol trafficking to the endoplasmic reticulum.
Kristiana I; Yang H; Brown AJ
Biochim Biophys Acta; 2008; 1781(11-12):724-30. PubMed ID: 18838129
[TBL] [Abstract][Full Text] [Related]
20. Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells.
Ebrahimi-Fakhari D; Wahlster L; Bartz F; Werenbeck-Ueding J; Praggastis M; Zhang J; Joggerst-Thomalla B; Theiss S; Grimm D; Ory DS; Runz H
Hum Mol Genet; 2016 Aug; 25(16):3588-3599. PubMed ID: 27378690
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
