110 related articles for article (PubMed ID: 19887335)
1. Insilico analysis of homocamptothecin (hCPT) analogues for anti-tumour activity.
Vadwai V; Devaraj S
Int J Bioinform Res Appl; 2009; 5(6):603-15. PubMed ID: 19887335
[TBL] [Abstract][Full Text] [Related]
2. Homocamptothecin, an E-ring-modified camptothecin analogue, generates new topoisomerase I-mediated DNA breaks.
Bailly C; Lansiaux A; Dassonneville L; Demarquay D; Coulomb H; Huchet M; Lavergne O; Bigg DC
Biochemistry; 1999 Nov; 38(47):15556-63. PubMed ID: 10569939
[TBL] [Abstract][Full Text] [Related]
3. Homocamptothecin, an E-ring modified camptothecin with enhanced lactone stability, retains topoisomerase I-targeted activity and antitumor properties.
Lesueur-Ginot L; Demarquay D; Kiss R; Kasprzyk PG; Dassonneville L; Bailly C; Camara J; Lavergne O; Bigg DC
Cancer Res; 1999 Jun; 59(12):2939-43. PubMed ID: 10383158
[TBL] [Abstract][Full Text] [Related]
4. A novel B-ring modified homocamptothecin, 12-Cl-hCPT, showing antiproliferative and topoisomerase I inhibitory activities superior to SN-38.
Bailly C; Laine W; Baldeyrou B; Demarquay D; Huchet M; Coulomb H; Lanco C; Lavergne O; Bigg DC
Anticancer Drug Des; 2001 Feb; 16(1):27-36. PubMed ID: 11762642
[TBL] [Abstract][Full Text] [Related]
5. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
Lavergne O; Lesueur-Ginot L; Pla Rodas F; Kasprzyk PG; Pommier J; Demarquay D; Prévost G; Ulibarri G; Rolland A; Schiano-Liberatore AM; Harnett J; Pons D; Camara J; Bigg DC
J Med Chem; 1998 Dec; 41(27):5410-9. PubMed ID: 9876111
[TBL] [Abstract][Full Text] [Related]
6. Activity of a novel camptothecin analogue, homocamptothecin, in camptothecin-resistant cell lines with topoisomerase I alterations.
Urasaki Y; Takebayashi Y; Pommier Y
Cancer Res; 2000 Dec; 60(23):6577-80. PubMed ID: 11118036
[TBL] [Abstract][Full Text] [Related]
7. Topoisomerase I-mediated antiproliferative activity of enantiomerically pure fluorinated homocamptothecins.
Lavergne O; Demarquay D; Bailly C; Lanco C; Rolland A; Huchet M; Coulomb H; Muller N; Baroggi N; Camara J; Le Breton C; Manginot E; Cazaux JB; Bigg DC
J Med Chem; 2000 Jun; 43(11):2285-9. PubMed ID: 10841808
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological evaluation of 7-alkenyl homocamptothecins as potent topoisomerase I inhibitors.
Zhu L; Zhang X; Lei N; Liu W; Miao Z; Zhuang C; Sheng C; Guo W; Dong G; Yao J; Cheng P; Zhang W
Chem Biodivers; 2012 Jun; 9(6):1084-94. PubMed ID: 22700227
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of new homocamptothecin analogs.
Luo Y; Yu S; Tong L; Huang Q; Lu W; Chen Y
Eur J Med Chem; 2012 Aug; 54():281-6. PubMed ID: 22647222
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of novel homocamptothecins conjugating with dihydropyrimidine derivatives as potent topoisomerase I inhibitors.
Zhu L; Cheng P; Lei N; Yao J; Sheng C; Zhuang C; Guo W; Liu W; Zhang Y; Dong G; Wang S; Miao Z; Zhang W
Arch Pharm (Weinheim); 2011 Nov; 344(11):726-34. PubMed ID: 21956522
[TBL] [Abstract][Full Text] [Related]
11. Homocamptothecins: E-ring modified CPT analogues.
Lavergne O; Demarquay D; Kasprzyk PG; Bigg DC
Ann N Y Acad Sci; 2000; 922():100-11. PubMed ID: 11193885
[TBL] [Abstract][Full Text] [Related]
12. The homocamptothecin BN 80915 is a highly potent orally active topoisomerase I poison.
Demarquay D; Huchet M; Coulomb H; Lesueur-Ginot L; Lavergne O; Kasprzyk PG; Bailly C; Camara J; Bigg DC
Anticancer Drugs; 2001 Jan; 12(1):9-19. PubMed ID: 11272292
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and biological assays of E-ring analogs of camptothecin and homocamptothecin.
Tangirala RS; Antony S; Agama K; Pommier Y; Anderson BD; Bevins R; Curran DP
Bioorg Med Chem; 2006 Sep; 14(18):6202-12. PubMed ID: 16793274
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological evaluation of novel 7-acyl homocamptothecins as Topoisomerase I inhibitors.
Liu W; Zhu L; Guo W; Zhuang C; Zhang Y; Sheng C; Cheng P; Yao J; Wang W; Dong G; Wang S; Miao Z; Zhang W
Eur J Med Chem; 2011 Jun; 46(6):2408-14. PubMed ID: 21463912
[TBL] [Abstract][Full Text] [Related]
15. Trifluoromethyl-promoted homocamptothecins: synthesis and biological activity.
Zhu L; Miao Z; Sheng C; Guo W; Yao J; Liu W; Che X; Wang W; Cheng P; Zhang W
Eur J Med Chem; 2010 Jul; 45(7):2726-32. PubMed ID: 20304538
[TBL] [Abstract][Full Text] [Related]
16. Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin.
Fan Y; Weinstein JN; Kohn KW; Shi LM; Pommier Y
J Med Chem; 1998 Jun; 41(13):2216-26. PubMed ID: 9632354
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and cytotoxicity of novel 20-O-linked homocamptothecin ester derivatives as potent topoisomerase I inhibitors.
Li DZ; Wang CY; Liu RH; Wang YM; Ji TF; Li YR; Pan XD
J Asian Nat Prod Res; 2013 Nov; 15(11):1179-88. PubMed ID: 24215541
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological evaluation of novel homocamptothecin analogues as potent antitumor agents.
Wang L; Xie S; Ma L; Chen Y; Lu W
Bioorg Med Chem; 2015 May; 23(9):1950-62. PubMed ID: 25835359
[TBL] [Abstract][Full Text] [Related]
19. Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies.
Laco GS; Du W; Kohlhagen G; Sayer JM; Jerina DM; Burke TG; Curran DP; Pommier Y
Bioorg Med Chem; 2004 Oct; 12(19):5225-35. PubMed ID: 15351405
[TBL] [Abstract][Full Text] [Related]
20. New homocamptothecins: synthesis, antitumor activity, and molecular modeling.
Miao Z; Sheng C; Zhang W; Ji H; Zhang J; Shao L; You L; Zhang M; Yao J; Che X
Bioorg Med Chem; 2008 Feb; 16(3):1493-510. PubMed ID: 18207748
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]