BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 19889539)

  • 1. Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA.
    Rawls KA; Lang PT; Takeuchi J; Imamura S; Baguley TD; Grundner C; Alber T; Ellman JA
    Bioorg Med Chem Lett; 2009 Dec; 19(24):6851-4. PubMed ID: 19889539
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors.
    Sens L; de Souza ACA; Pacheco LA; Menegatti ACO; Mori M; Mascarello A; Nunes RJ; Terenzi H
    Bioorg Med Chem; 2018 Nov; 26(21):5742-5750. PubMed ID: 30389409
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Organocatalytic multicomponent reaction for the acquisition of a selective inhibitor of mPTPB, a virulence factor of tuberculosis.
    He R; Zeng LF; He Y; Wu L; Gunawan AM; Zhang ZY
    Chem Commun (Camb); 2013 Mar; 49(20):2064-6. PubMed ID: 23380872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.
    He R; Yu Z; He Y; Zeng LF; Xu J; Wu L; Gunawan AM; Wang L; Jiang ZX; Zhang ZY
    ChemMedChem; 2010 Dec; 5(12):2051-6. PubMed ID: 20957718
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Highly Potent and Selective
    Ruddraraju KV; Aggarwal D; Niu C; Baker EA; Zhang RY; Wu L; Zhang ZY
    J Med Chem; 2020 Sep; 63(17):9212-9227. PubMed ID: 32787087
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase A (MptpA) inhibitors based on natural products and a fragment-based approach.
    Manger M; Scheck M; Prinz H; von Kries JP; Langer T; Saxena K; Schwalbe H; Fürstner A; Rademann J; Waldmann H
    Chembiochem; 2005 Oct; 6(10):1749-53. PubMed ID: 16196020
    [No Abstract]   [Full Text] [Related]  

  • 7. Docking- and pharmacophore-based virtual screening for the identification of novel Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB) inhibitor with a thiobarbiturate scaffold.
    Zhang D; Lin Y; Chen X; Zhao W; Chen D; Gao M; Wang Q; Wang B; Huang H; Lu Y; Lu Y
    Bioorg Chem; 2019 Apr; 85():229-239. PubMed ID: 30641319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, biological evaluation, and molecular modeling of chalcone derivatives as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatases (PtpA and PtpB).
    Chiaradia LD; Martins PG; Cordeiro MN; Guido RV; Ecco G; Andricopulo AD; Yunes RA; Vernal J; Nunes RJ; Terenzi H
    J Med Chem; 2012 Jan; 55(1):390-402. PubMed ID: 22136336
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mycobacterium tuberculosis-Secreted Tyrosine Phosphatases as Targets Against Tuberculosis: Exploring Natural Sources in Searching for New Drugs.
    Mascarello A; Chiaradia-Delatorre LD; Mori M; Terenzi H; Botta B
    Curr Pharm Des; 2016; 22(12):1561-9. PubMed ID: 26759082
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting mycobacterium protein tyrosine phosphatase B for antituberculosis agents.
    Zhou B; He Y; Zhang X; Xu J; Luo Y; Wang Y; Franzblau SG; Yang Z; Chan RJ; Liu Y; Zheng J; Zhang ZY
    Proc Natl Acad Sci U S A; 2010 Mar; 107(10):4573-8. PubMed ID: 20167798
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Elucidation of Mycobacterium tuberculosis type II dehydroquinase inhibitors using a fragment elaboration strategy.
    Tran AT; West NP; Britton WJ; Payne RJ
    ChemMedChem; 2012 Jun; 7(6):1031-43. PubMed ID: 22461418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth.
    Mascarello A; Chiaradia LD; Vernal J; Villarino A; Guido RV; Perizzolo P; Poirier V; Wong D; Martins PG; Nunes RJ; Yunes RA; Andricopulo AD; Av-Gay Y; Terenzi H
    Bioorg Med Chem; 2010 Jun; 18(11):3783-9. PubMed ID: 20462762
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mycobacterium tuberculosis Low Molecular Weight Phosphatases (MPtpA and MPtpB): From Biological Insight to Inhibitors.
    Fanzani L; Porta F; Meneghetti F; Villa S; Gelain A; Lucarelli AP; Parisini E
    Curr Med Chem; 2015; 22(27):3110-32. PubMed ID: 26264920
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of thiazolidinones spiro-fused to indolin-2-ones as potent and selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase B.
    Vintonyak VV; Warburg K; Kruse H; Grimme S; Hübel K; Rauh D; Waldmann H
    Angew Chem Int Ed Engl; 2010 Aug; 49(34):5902-5. PubMed ID: 20632348
    [No Abstract]   [Full Text] [Related]  

  • 15. [Advances in the study of Mycobacterium tuberculosis protein phosphatase and its inhibitors].
    Teng TS; Wang HH; Xie JP
    Yao Xue Xue Bao; 2011 Dec; 46(12):1420-8. PubMed ID: 22375413
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Chemical synthesis and biological evaluation of triazole derivatives as inhibitors of InhA and antituberculosis agents.
    Menendez C; Chollet A; Rodriguez F; Inard C; Pasca MR; Lherbet C; Baltas M
    Eur J Med Chem; 2012 Jun; 52():275-83. PubMed ID: 22483635
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mycobacterium tuberculosis-secreted phosphatases: from pathogenesis to targets for TB drug development.
    Wong D; Chao JD; Av-Gay Y
    Trends Microbiol; 2013 Feb; 21(2):100-9. PubMed ID: 23084287
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.
    Silva AP; Tabernero L
    Future Med Chem; 2010 Aug; 2(8):1325-37. PubMed ID: 21426021
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of fusarielin M as a novel inhibitor of Mycobacterium tuberculosis protein tyrosine phosphatase B (MptpB).
    Chen D; Liu L; Lu Y; Chen S
    Bioorg Chem; 2021 Jan; 106():104495. PubMed ID: 33293055
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of inhibitors targeting polyketide synthase 13 of Mycobacterium tuberculosis as antituberculosis drug leads.
    Wang X; Zhao W; Wang B; Ding W; Guo H; Zhao H; Meng J; Liu S; Lu Y; Liu Y; Zhang D
    Bioorg Chem; 2021 Sep; 114():105110. PubMed ID: 34175719
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.