BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 19891735)

  • 1. Multi-targeted neuroprotection by the HSV-2 gene ICP10PK includes robust bystander activity through PI3-K/Akt and/or MEK/ERK-dependent neuronal release of vascular endothelial growth factor and fractalkine.
    Laing JM; Smith CC; Aurelian L
    J Neurochem; 2010 Feb; 112(3):662-76. PubMed ID: 19891735
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The growth compromised HSV-2 mutant DeltaRR prevents kainic acid-induced apoptosis and loss of function in organotypic hippocampal cultures.
    Gober MD; Laing JM; Thompson SM; Aurelian L
    Brain Res; 2006 Nov; 1119(1):26-39. PubMed ID: 17020750
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Growth-compromised HSV-2 vector Delta RR protects from N-methyl-D-aspartate-induced neuronal degeneration through redundant activation of the MEK/ERK and PI3-K/Akt survival pathways, either one of which overrides apoptotic cascades.
    Laing JM; Golembewski EK; Wales SQ; Liu J; Jafri MS; Yarowsky PJ; Aurelian L
    J Neurosci Res; 2008 Feb; 86(2):378-91. PubMed ID: 17893911
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The HSV-2 protein ICP10PK prevents neuronal apoptosis and loss of function in an in vivo model of neurodegeneration associated with glutamate excitotoxicity.
    Golembewski EK; Wales SQ; Aurelian L; Yarowsky PJ
    Exp Neurol; 2007 Feb; 203(2):381-93. PubMed ID: 17046754
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation.
    Wales SQ; Li B; Laing JM; Aurelian L
    J Neurochem; 2007 Oct; 103(1):365-79. PubMed ID: 17877640
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway.
    Subramaniam S; Shahani N; Strelau J; Laliberté C; Brandt R; Kaplan D; Unsicker K
    J Neurosci; 2005 Mar; 25(11):2838-52. PubMed ID: 15772344
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Extracellular HMGB1 released by NMDA treatment confers neuronal apoptosis via RAGE-p38 MAPK/ERK signaling pathway.
    Kim SW; Lim CM; Kim JB; Shin JH; Lee S; Lee M; Lee JK
    Neurotox Res; 2011 Aug; 20(2):159-69. PubMed ID: 21116767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The herpes simplex virus type 2 R1 protein kinase (ICP10 PK) blocks apoptosis in hippocampal neurons, involving activation of the MEK/MAPK survival pathway.
    Perkins D; Pereira EF; Gober M; Yarowsky PJ; Aurelian L
    J Virol; 2002 Feb; 76(3):1435-49. PubMed ID: 11773417
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuroprotection by BDNF against glutamate-induced apoptotic cell death is mediated by ERK and PI3-kinase pathways.
    Almeida RD; Manadas BJ; Melo CV; Gomes JR; Mendes CS; Grãos MM; Carvalho RF; Carvalho AP; Duarte CB
    Cell Death Differ; 2005 Oct; 12(10):1329-43. PubMed ID: 15905876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Fractalkine stimulates angiogenesis by activating the Raf-1/MEK/ERK- and PI3K/Akt/eNOS-dependent signal pathways.
    Lee SJ; Namkoong S; Kim YM; Kim CK; Lee H; Ha KS; Chung HT; Kwon YG; Kim YM
    Am J Physiol Heart Circ Physiol; 2006 Dec; 291(6):H2836-46. PubMed ID: 16877565
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VEGF-induced activation of the PI3-K/Akt pathway reduces mutant SOD1-mediated motor neuron cell death.
    Li B; Xu W; Luo C; Gozal D; Liu R
    Brain Res Mol Brain Res; 2003 Mar; 111(1-2):155-64. PubMed ID: 12654515
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons.
    Cook A; Hippensteel R; Shimizu S; Nicolai J; Fatatis A; Meucci O
    J Biol Chem; 2010 Apr; 285(14):10563-71. PubMed ID: 20124406
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Astrocyte-conditioned medium protecting hippocampal neurons in primary cultures against corticosterone-induced damages via PI3-K/Akt signal pathway.
    Zhu ZH; Yang R; Fu X; Wang YQ; Wu GC
    Brain Res; 2006 Oct; 1114(1):1-10. PubMed ID: 16930567
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neuroprotection by transforming growth factor-beta1 involves activation of nuclear factor-kappaB through phosphatidylinositol-3-OH kinase/Akt and mitogen-activated protein kinase-extracellular-signal regulated kinase1,2 signaling pathways.
    Zhu Y; Culmsee C; Klumpp S; Krieglstein J
    Neuroscience; 2004; 123(4):897-906. PubMed ID: 14751283
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The herpes simplex virus type 2 protein ICP10PK: a master of versatility.
    Smith CC
    Front Biosci; 2005 Sep; 10():2820-31. PubMed ID: 15970536
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DeltaRR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis.
    Laing JM; Aurelian L
    Genet Vaccines Ther; 2008 Jan; 6():1. PubMed ID: 18179717
    [TBL] [Abstract][Full Text] [Related]  

  • 17. ICP10PK inhibits calpain-dependent release of apoptosis-inducing factor and programmed cell death in response to the toxin MPP+.
    Wales SQ; Laing JM; Chen L; Aurelian L
    Gene Ther; 2008 Oct; 15(20):1397-409. PubMed ID: 18496573
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 5-HT receptors couple to activation of Akt, but not extracellular-regulated kinase (ERK), in cultured hippocampal neurons.
    Cowen DS; Johnson-Farley NN; Travkina T
    J Neurochem; 2005 May; 93(4):910-7. PubMed ID: 15857394
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-kappaB: neuroprotective implications.
    Nam KN; Son MS; Park JH; Lee EH
    Neuropharmacology; 2008 Oct; 55(5):819-25. PubMed ID: 18657551
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutamate released by Japanese encephalitis virus-infected microglia involves TNF-α signaling and contributes to neuronal death.
    Chen CJ; Ou YC; Chang CY; Pan HC; Liao SL; Chen SY; Raung SL; Lai CY
    Glia; 2012 Mar; 60(3):487-501. PubMed ID: 22144112
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.