162 related articles for article (PubMed ID: 19893055)
1. An industry perspective on the utility of short-term carcinogenicity testing in transgenic mice in pharmaceutical development.
Storer RD; Sistare FD; Reddy MV; DeGeorge JJ
Toxicol Pathol; 2010 Jan; 38(1):51-61. PubMed ID: 19893055
[TBL] [Abstract][Full Text] [Related]
2. Evaluation of carcinogenicity studies of medicinal products for human use authorised via the European centralised procedure (1995-2009).
Friedrich A; Olejniczak K
Regul Toxicol Pharmacol; 2011 Jul; 60(2):225-48. PubMed ID: 21513764
[TBL] [Abstract][Full Text] [Related]
3. An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines.
Sistare FD; Morton D; Alden C; Christensen J; Keller D; Jonghe SD; Storer RD; Reddy MV; Kraynak A; Trela B; Bienvenu JG; Bjurström S; Bosmans V; Brewster D; Colman K; Dominick M; Evans J; Hailey JR; Kinter L; Liu M; Mahrt C; Marien D; Myer J; Perry R; Potenta D; Roth A; Sherratt P; Singer T; Slim R; Soper K; Fransson-Steen R; Stoltz J; Turner O; Turnquist S; van Heerden M; Woicke J; DeGeorge JJ
Toxicol Pathol; 2011 Jun; 39(4):716-44. PubMed ID: 21666103
[TBL] [Abstract][Full Text] [Related]
4. Alternative mouse models for carcinogenicity assessment: industry use and issues with pathology interpretation.
Long GG; Morton D; Peters T; Short B; Skydsgaard M
Toxicol Pathol; 2010 Jan; 38(1):43-50. PubMed ID: 19915137
[TBL] [Abstract][Full Text] [Related]
5. The utility of the K6/ODC transgenic mouse as an alternative short term dermal model for carcinogenicity testing of pharmaceuticals.
Miller TJ; Honchel R; Espandiari P; Knapton A; Zhang J; Sistare FD; Hanig JP
Regul Toxicol Pharmacol; 2008 Feb; 50(1):87-97. PubMed ID: 18069108
[TBL] [Abstract][Full Text] [Related]
6. The in vivo rodent test systems for assessment of carcinogenic potential.
van der Laan JW; Spindler P
Regul Toxicol Pharmacol; 2002 Feb; 35(1):122-5. PubMed ID: 11846641
[TBL] [Abstract][Full Text] [Related]
7. Regulatory Forum commentary: alternative mouse models for future cancer risk assessment.
Morton D; Sistare FD; Nambiar PR; Turner OC; Radi Z; Bower N
Toxicol Pathol; 2014 Jul; 42(5):799-806. PubMed ID: 23965809
[TBL] [Abstract][Full Text] [Related]
8. Mouse-specific carcinogens: an assessment of hazard and significance for validation of short-term carcinogenicity bioassays in transgenic mice.
Battershill JM; Fielder RJ
Hum Exp Toxicol; 1998 Apr; 17(4):193-205. PubMed ID: 9617631
[TBL] [Abstract][Full Text] [Related]
9. Review of alternative methods of carcinogenicity testing and evaluation of human pharmaceuticals.
Van Deun K; Van Cauteren H; Vandenberghe J; Canning M; Vanparys P; Coussement W
Adverse Drug React Toxicol Rev; 1997 Nov; 16(4):215-33. PubMed ID: 9608857
[TBL] [Abstract][Full Text] [Related]
10. Evaluation of the Xpa-deficient transgenic mouse model for short-term carcinogenicity testing: 9-month studies with haloperidol, reserpine, phenacetin, and D-mannitol.
Lina BA; Woutersen RA; Bruijntjes JP; van Benthem J; van den Berg JA; Monbaliu J; Thoolen BJ; Beems RB; van Kreijl CF
Toxicol Pathol; 2004; 32(2):192-201. PubMed ID: 15200157
[TBL] [Abstract][Full Text] [Related]
11. The Tg rasH2 mouse in cancer hazard identification.
Morton D; Alden CL; Roth AJ; Usui T
Toxicol Pathol; 2002; 30(1):139-46. PubMed ID: 11890467
[TBL] [Abstract][Full Text] [Related]
12. The Trp53 hemizygous mouse in pharmaceutical development: points to consider for pathologists.
Floyd E; Mann P; Long G; Ochoa R
Toxicol Pathol; 2002; 30(1):147-56. PubMed ID: 11890468
[TBL] [Abstract][Full Text] [Related]
13. The transgenic mouse assay as an alternative test method for regulatory carcinogenicity studies--implications for REACH.
Wells MY; Williams ES
Regul Toxicol Pharmacol; 2009 Mar; 53(2):150-5. PubMed ID: 19126422
[TBL] [Abstract][Full Text] [Related]
14. Transgene stability and features of rasH2 mice as an animal model for short-term carcinogenicity testing.
Suemizu H; Muguruma K; Maruyama C; Tomisawa M; Kimura M; Hioki K; Shimozawa N; Ohnishi Y; Tamaoki N; Nomura T
Mol Carcinog; 2002 May; 34(1):1-9. PubMed ID: 12112317
[TBL] [Abstract][Full Text] [Related]
15. How useful are chronic (life-span) toxicology studies in rodents in identifying pharmaceuticals that pose a carcinogenic risk to humans?
Monro A
Adverse Drug React Toxicol Rev; 1993; 12(1):5-34. PubMed ID: 8513076
[TBL] [Abstract][Full Text] [Related]
16. Transgenic tumor models for carcinogen identification: the heterozygous Trp53-deficient and RasH2 mouse lines.
Storer RD; French JE; Donehower LA; Gulezian D; Mitsumori K; Recio L; Schiestl RH; Sistare FD; Tamaoki N; Usui T; van Steeg H;
Mutat Res; 2003 Oct; 540(2):165-76. PubMed ID: 14550500
[TBL] [Abstract][Full Text] [Related]
17. Use of rasH2 transgenic mice for carcinogenesis testing of medical implants.
Palazzi X; Kergozien-Framery S
Exp Toxicol Pathol; 2009 Sep; 61(5):433-41. PubMed ID: 19062264
[TBL] [Abstract][Full Text] [Related]
18. Establishing a laboratory animal model from a transgenic animal: RasH2 mice as a model for carcinogenicity studies in regulatory science.
Urano K; Tamaoki N; Nomura T
Vet Pathol; 2012 Jan; 49(1):16-23. PubMed ID: 22146850
[TBL] [Abstract][Full Text] [Related]
19. Current status and use of short/medium term models for carcinogenicity testing of pharmaceuticals--scientific perspective.
Storer RD
Toxicol Lett; 2000 Mar; 112-113():557-66. PubMed ID: 10720780
[TBL] [Abstract][Full Text] [Related]
20. Tg.rasH2 Mouse Model for Assessing Carcinogenic Potential of Pharmaceuticals: Industry Survey of Current Practices.
Bogdanffy MS; Lesniak J; Mangipudy R; Sistare FD; Colman K; Garcia-Tapia D; Monticello T; Blanset D
Int J Toxicol; 2020; 39(3):198-206. PubMed ID: 32372678
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]