BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 19894761)

  • 21. An examination of the source of the tyrosyl radical in ovine prostaglandin endoperoxide synthase-1.
    Hsi LC; Hoganson CW; Babcock GT; Garavito RM; Smith WL
    Biochem Biophys Res Commun; 1995 Feb; 207(2):652-60. PubMed ID: 7864856
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).
    Pouplana R; Lozano JJ; Ruiz J
    J Mol Graph Model; 2002 Jan; 20(4):329-43. PubMed ID: 11858641
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Histidine 386 and its role in cyclooxygenase and peroxidase catalysis by prostaglandin-endoperoxide H synthases.
    Seibold SA; Ball T; Hsi LC; Mills DA; Abeysinghe RD; Micielli R; Rieke CJ; Cukier RI; Smith WL
    J Biol Chem; 2003 Nov; 278(46):46163-70. PubMed ID: 12952981
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Substitution of tyrosine for the proximal histidine ligand to the heme of prostaglandin endoperoxide synthase 2: implications for the mechanism of cyclooxygenase activation and catalysis.
    Goodwin DC; Rowlinson SW; Marnett LJ
    Biochemistry; 2000 May; 39(18):5422-32. PubMed ID: 10820014
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Higher oxidation states of prostaglandin H synthase. EPR study of a transient tyrosyl radical in the enzyme during the peroxidase reaction.
    Karthein R; Dietz R; Nastainczyk W; Ruf HH
    Eur J Biochem; 1988 Jan; 171(1-2):313-20. PubMed ID: 2828053
    [TBL] [Abstract][Full Text] [Related]  

  • 26. High-field EPR study of tyrosyl radicals in prostaglandin H(2) synthase-1.
    Dorlet P; Seibold SA; Babcock GT; Gerfen GJ; Smith WL; Tsai AL; Un S
    Biochemistry; 2002 May; 41(19):6107-14. PubMed ID: 11994006
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Involvement of arginine 120, glutamate 524, and tyrosine 355 in the binding of arachidonate and 2-phenylpropionic acid inhibitors to the cyclooxygenase active site of ovine prostaglandin endoperoxide H synthase-1.
    Bhattacharyya DK; Lecomte M; Rieke CJ; Garavito M; Smith WL
    J Biol Chem; 1996 Jan; 271(4):2179-84. PubMed ID: 8567676
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Role of Asn-382 and Thr-383 in activation and inactivation of human prostaglandin H synthase cyclooxygenase catalysis.
    Bambai B; Rogge CE; Stec B; Kulmacz RJ
    J Biol Chem; 2004 Feb; 279(6):4084-92. PubMed ID: 14625295
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Prostaglandin H synthase: resolved and unresolved mechanistic issues.
    Tsai AL; Kulmacz RJ
    Arch Biochem Biophys; 2010 Jan; 493(1):103-24. PubMed ID: 19728984
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers.
    Sidhu RS; Lee JY; Yuan C; Smith WL
    Biochemistry; 2010 Aug; 49(33):7069-79. PubMed ID: 20669977
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The enzymology of prostaglandin endoperoxide H synthases-1 and -2.
    Smith WL; Song I
    Prostaglandins Other Lipid Mediat; 2002 Aug; 68-69():115-28. PubMed ID: 12432913
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Electron spin resonance investigation of tyrosyl radicals of prostaglandin H synthase. Relation to enzyme catalysis.
    Lassmann G; Odenwaller R; Curtis JF; DeGray JA; Mason RP; Marnett LJ; Eling TE
    J Biol Chem; 1991 Oct; 266(30):20045-55. PubMed ID: 1657911
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure-based QSAR study on differential inhibition of human prostaglandin endoperoxide H synthase-2 (COX-2) by nonsteroidal anti-inflammatory drugs.
    Pouplana R; Lozano JJ; PĂ©rez C; Ruiz J
    J Comput Aided Mol Des; 2002 Oct; 16(10):683-709. PubMed ID: 12650588
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cyclooxygenase inactivation kinetics during reaction of prostaglandin H synthase-1 with peroxide.
    Wu G; Kulmacz RJ; Tsai AL
    Biochemistry; 2003 Nov; 42(46):13772-7. PubMed ID: 14622024
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Electron paramagnetic resonance and electron nuclear double resonance spectroscopic identification and characterization of the tyrosyl radicals in prostaglandin H synthase 1.
    Shi W; Hoganson CW; Espe M; Bender CJ; Babcock GT; Palmer G; Kulmacz RJ; Tsai Al
    Biochemistry; 2000 Apr; 39(14):4112-21. PubMed ID: 10747802
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.
    Wu G; Vuletich JL; Kulmacz RJ; Osawa Y; Tsai AL
    J Biol Chem; 2001 Jun; 276(23):19879-88. PubMed ID: 11279106
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Tyrosyl radicals in prostaglandin H synthase-1 and -2.
    Tsai A; Kulmacz RJ
    Prostaglandins Other Lipid Mediat; 2000 Aug; 62(3):231-54. PubMed ID: 10963792
    [No Abstract]   [Full Text] [Related]  

  • 38. Prostaglandin H synthase: spectroscopic studies of the interaction with hydroperoxides and with indomethacin.
    Kulmacz RJ; Ren Y; Tsai AL; Palmer G
    Biochemistry; 1990 Sep; 29(37):8760-71. PubMed ID: 2176834
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations.
    Selinsky BS; Gupta K; Sharkey CT; Loll PJ
    Biochemistry; 2001 May; 40(17):5172-80. PubMed ID: 11318639
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Direction of strategic use: a new classification of non-steroidal anti-inflammatory drugs based on reactivity with peroxidase].
    Miura T
    Yakugaku Zasshi; 2013; 133(6):681-9. PubMed ID: 23474686
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.