BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 19903830)

  • 1. Identification of novel small-molecule agonists for human formyl peptide receptors and pharmacophore models of their recognition.
    Kirpotina LN; Khlebnikov AI; Schepetkin IA; Ye RD; Rabiet MJ; Jutila MA; Quinn MT
    Mol Pharmacol; 2010 Feb; 77(2):159-70. PubMed ID: 19903830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gastrin-releasing peptide/neuromedin B receptor antagonists PD176252, PD168368, and related analogs are potent agonists of human formyl-peptide receptors.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Jutila MA; Quinn MT
    Mol Pharmacol; 2011 Jan; 79(1):77-90. PubMed ID: 20943772
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stable formyl peptide receptor agonists that activate the neutrophil NADPH-oxidase identified through screening of a compound library.
    Forsman H; Kalderén C; Nordin A; Nordling E; Jensen AJ; Dahlgren C
    Biochem Pharmacol; 2011 Feb; 81(3):402-11. PubMed ID: 21095183
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3-(1H-indol-3-yl)-2-[3-(4-nitrophenyl)ureido]propanamide enantiomers with human formyl-peptide receptor agonist activity: molecular modeling of chiral recognition by FPR2.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Leopoldo M; Lucente E; Lacivita E; De Giorgio P; Quinn MT
    Biochem Pharmacol; 2013 Feb; 85(3):404-16. PubMed ID: 23219934
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Peptide length and folding state govern the capacity of staphylococcal β-type phenol-soluble modulins to activate human formyl-peptide receptors 1 or 2.
    Kretschmer D; Rautenberg M; Linke D; Peschel A
    J Leukoc Biol; 2015 Apr; 97(4):689-97. PubMed ID: 25724390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular docking of 2-(benzimidazol-2-ylthio)-N-phenylacetamide-derived small-molecule agonists of human formyl peptide receptor 1.
    Khlebnikov AI; Schepetkin IA; Kirpotina LN; Brive L; Dahlgren C; Jutila MA; Quinn MT
    J Mol Model; 2012 Jun; 18(6):2831-43. PubMed ID: 22127612
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mitocryptide-2: Identification of Its Minimum Structure for Specific Activation of FPR2-Possible Receptor Switching from FPR2 to FPR1 by Its Physiological C-terminal Cleavages.
    Marutani T; Nishino K; Miyaji T; Kamada K; Ohura K; Kiso Y; Mukai H
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33920954
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists.
    Giovannoni MP; Schepetkin IA; Cilibrizzi A; Crocetti L; Khlebnikov AI; Dahlgren C; Graziano A; Dal Piaz V; Kirpotina LN; Zerbinati S; Vergelli C; Quinn MT
    Eur J Med Chem; 2013 Jun; 64():512-28. PubMed ID: 23685570
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones.
    Schepetkin IA; Kirpotina LN; Khlebnikov AI; Cheng N; Ye RD; Quinn MT
    Biochem Pharmacol; 2014 Dec; 92(4):627-41. PubMed ID: 25450672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 4-Aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-ones as N-formyl peptide receptor 1 (FPR1) antagonists.
    Kirpotina LN; Schepetkin IA; Khlebnikov AI; Ruban OI; Ge Y; Ye RD; Kominsky DJ; Quinn MT
    Biochem Pharmacol; 2017 Oct; 142():120-132. PubMed ID: 28690139
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective agonists and antagonists of formylpeptide receptors: duplex flow cytometry and mixture-based positional scanning libraries.
    Pinilla C; Edwards BS; Appel JR; Yates-Gibbins T; Giulianotti MA; Medina-Franco JL; Young SM; Santos RG; Sklar LA; Houghten RA
    Mol Pharmacol; 2013 Sep; 84(3):314-24. PubMed ID: 23788657
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of small molecule non-peptide formyl peptide receptor (FPR) ligands and molecular modeling of their recognition.
    Schepetkin IA; Khlebnikov AI; Giovannoni MP; Kirpotina LN; Cilibrizzi A; Quinn MT
    Curr Med Chem; 2014; 21(13):1478-504. PubMed ID: 24350845
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 6-methyl-2,4-disubstituted pyridazin-3(2H)-ones: a novel class of small-molecule agonists for formyl peptide receptors.
    Cilibrizzi A; Quinn MT; Kirpotina LN; Schepetkin IA; Holderness J; Ye RD; Rabiet MJ; Biancalani C; Cesari N; Graziano A; Vergelli C; Pieretti S; Dal Piaz V; Giovannoni MP
    J Med Chem; 2009 Aug; 52(16):5044-57. PubMed ID: 19639995
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question.
    Winther M; Holdfeldt A; Sundqvist M; Rajabkhani Z; Gabl M; Bylund J; Dahlgren C; Forsman H
    PLoS One; 2017; 12(9):e0185132. PubMed ID: 28934373
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structural determinants for the interaction of formyl peptide receptor 2 with peptide ligands.
    He HQ; Troksa EL; Caltabiano G; Pardo L; Ye RD
    J Biol Chem; 2014 Jan; 289(4):2295-306. PubMed ID: 24285541
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of C-terminal phosphorylation sites of N-formyl peptide receptor-1 (FPR1) in human blood neutrophils.
    Maaty WS; Lord CI; Gripentrog JM; Riesselman M; Keren-Aviram G; Liu T; Dratz EA; Bothner B; Jesaitis AJ
    J Biol Chem; 2013 Sep; 288(38):27042-27058. PubMed ID: 23873933
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A neutrophil inhibitory pepducin derived from FPR1 expected to target FPR1 signaling hijacks the closely related FPR2 instead.
    Winther M; Gabl M; Welin A; Dahlgren C; Forsman H
    FEBS Lett; 2015 Jul; 589(15):1832-9. PubMed ID: 26071379
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2 complex.
    Lind S; Dahlgren C; Holmdahl R; Olofsson P; Forsman H
    J Leukoc Biol; 2021 Jun; 109(6):1105-1120. PubMed ID: 33040403
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural changes of the ligand and of the receptor alters the receptor preference for neutrophil activating peptides starting with a formylmethionyl group.
    Forsman H; Winther M; Gabl M; Skovbakke SL; Boulay F; Rabiet MJ; Dahlgren C
    Biochim Biophys Acta; 2015 Jan; 1853(1):192-200. PubMed ID: 25447672
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Computational structure-activity relationship analysis of small-molecule agonists for human formyl peptide receptors.
    Khlebnikov AI; Schepetkin IA; Quinn MT
    Eur J Med Chem; 2010 Nov; 45(11):5406-19. PubMed ID: 20870313
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.