269 related articles for article (PubMed ID: 19903830)
21. The leukocyte chemotactic receptor FPR2, but not the closely related FPR1, is sensitive to cell-penetrating pepducins with amino acid sequences descending from the third intracellular receptor loop.
Forsman H; Bylund J; Oprea TI; Karlsson A; Boulay F; Rabiet MJ; Dahlgren C
Biochim Biophys Acta; 2013 Aug; 1833(8):1914-23. PubMed ID: 23562731
[TBL] [Abstract][Full Text] [Related]
22. The formyl peptide receptors FPR1 and FPR2 as targets for inflammatory disorders: recent advances in the development of small-molecule agonists.
Yi X; Tran E; Odiba JO; Qin CX; Ritchie RH; Baell JB
Eur J Med Chem; 2024 Feb; 265():115989. PubMed ID: 38199163
[TBL] [Abstract][Full Text] [Related]
23. Honokiol suppresses formyl peptide-induced human neutrophil activation by blocking formyl peptide receptor 1.
Liu FC; Yu HP; Syu YT; Fang JY; Lin CF; Chang SH; Lee YT; Hwang TL
Sci Rep; 2017 Jul; 7(1):6718. PubMed ID: 28751674
[TBL] [Abstract][Full Text] [Related]
24. Novel formyl peptide receptor (FPR) agonists with pyridinone and pyrimidindione scaffolds that are potentially useful for the treatment of rheumatoid arthritis.
Crocetti L; Vergelli C; Guerrini G; Cantini N; Kirpotina LN; Schepetkin IA; Quinn MT; Parisio C; Di Cesare Mannelli L; Ghelardini C; Giovannoni MP
Bioorg Chem; 2020 Jul; 100():103880. PubMed ID: 32388428
[TBL] [Abstract][Full Text] [Related]
25. Design, synthesis, and biological evaluation of novel pyrrolidinone small-molecule Formyl peptide receptor 2 agonists.
Maciuszek M; Ortega-Gomez A; Maas SL; Garrido-Mesa J; Ferraro B; Perretti M; Merritt A; Nicolaes GAF; Soehnlein O; Chapman TM
Eur J Med Chem; 2021 Dec; 226():113805. PubMed ID: 34536667
[TBL] [Abstract][Full Text] [Related]
26. Non-peptide ligand binding to the formyl peptide receptor FPR2--A comparison to peptide ligand binding modes.
Stepniewski TM; Filipek S
Bioorg Med Chem; 2015 Jul; 23(14):4072-81. PubMed ID: 25882522
[TBL] [Abstract][Full Text] [Related]
27. High-throughput screening for small-molecule activators of neutrophils: identification of novel N-formyl peptide receptor agonists.
Schepetkin IA; Kirpotina LN; Khlebnikov AI; Quinn MT
Mol Pharmacol; 2007 Apr; 71(4):1061-74. PubMed ID: 17229869
[TBL] [Abstract][Full Text] [Related]
28. Synthesis of Five- and Six-Membered N-Phenylacetamido Substituted Heterocycles as Formyl Peptide Receptor Agonists.
Vergelli C; Schepetkin IA; Ciciani G; Cilibrizzi A; Crocetti L; Giovannoni MP; Guerrini G; Iacovone A; Kirpotina LN; Ye RD; Quinn MT
Drug Dev Res; 2017 Feb; 78(1):49-62. PubMed ID: 27859446
[TBL] [Abstract][Full Text] [Related]
29. The proteolytically stable peptidomimetic Pam-(Lys-βNSpe)6-NH2 selectively inhibits human neutrophil activation via formyl peptide receptor 2.
Skovbakke SL; Heegaard PM; Larsen CJ; Franzyk H; Forsman H; Dahlgren C
Biochem Pharmacol; 2015 Jan; 93(2):182-95. PubMed ID: 25462815
[TBL] [Abstract][Full Text] [Related]
30. Structural Determinants in the
Viklund M; Fredriksson J; Holdfeldt A; Lind S; Franzyk H; Dahlgren C; Sundqvist M; Forsman H
J Immunol; 2022 Apr; 208(7):1632-1641. PubMed ID: 35321878
[TBL] [Abstract][Full Text] [Related]
31. Small-molecule-biased formyl peptide receptor agonist compound 17b protects against myocardial ischaemia-reperfusion injury in mice.
Qin CX; May LT; Li R; Cao N; Rosli S; Deo M; Alexander AE; Horlock D; Bourke JE; Yang YH; Stewart AG; Kaye DM; Du XJ; Sexton PM; Christopoulos A; Gao XM; Ritchie RH
Nat Commun; 2017 Feb; 8():14232. PubMed ID: 28169296
[TBL] [Abstract][Full Text] [Related]
32. Formyl peptide receptor 1 and 2 dual agonist inhibits human neutrophil chemotaxis by the induction of chemoattractant receptor cross-desensitization.
Sogawa Y; Ohyama T; Maeda H; Hirahara K
J Pharmacol Sci; 2011; 115(1):63-8. PubMed ID: 21173551
[TBL] [Abstract][Full Text] [Related]
33. Structural characterization and inhibitory profile of formyl peptide receptor 2 selective peptides descending from a PIP2-binding domain of gelsolin.
Forsman H; Andréasson E; Karlsson J; Boulay F; Rabiet MJ; Dahlgren C
J Immunol; 2012 Jul; 189(2):629-37. PubMed ID: 22706076
[TBL] [Abstract][Full Text] [Related]
34. A Critical Role of Formyl Peptide Receptors in Host Defense against
Zhang M; Gao JL; Chen K; Yoshimura T; Liang W; Gong W; Li X; Huang J; McDermott DH; Murphy PM; Wang X; Wang JM
J Immunol; 2020 May; 204(9):2464-2473. PubMed ID: 32221037
[TBL] [Abstract][Full Text] [Related]
35. Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949.
Lind S; Sundqvist M; Holmdahl R; Dahlgren C; Forsman H; Olofsson P
Biochem Pharmacol; 2019 Aug; 166():163-173. PubMed ID: 31085160
[TBL] [Abstract][Full Text] [Related]
36. Novel 3-(1H-indol-3-yl)-2-[3-(4-methoxyphenyl)ureido]propanamides as selective agonists of human formyl-peptide receptor 2.
Lacivita E; Schepetkin IA; Stama ML; Kirpotina LN; Colabufo NA; Perrone R; Khlebnikov AI; Quinn MT; Leopoldo M
Bioorg Med Chem; 2015 Jul; 23(14):3913-24. PubMed ID: 25549897
[TBL] [Abstract][Full Text] [Related]
37. The FPR2-specific ligand MMK-1 activates the neutrophil NADPH-oxidase, but triggers no unique pathway for opening of plasma membrane calcium channels.
Karlsson J; Stenfeldt AL; Rabiet MJ; Bylund J; Forsman HF; Dahlgren C
Cell Calcium; 2009 May; 45(5):431-8. PubMed ID: 19282028
[TBL] [Abstract][Full Text] [Related]
38. A pepducin derived from the third intracellular loop of FPR2 is a partial agonist for direct activation of this receptor in neutrophils but a full agonist for cross-talk triggered reactivation of FPR2.
Gabl M; Winther M; Skovbakke SL; Bylund J; Dahlgren C; Forsman H
PLoS One; 2014; 9(10):e109516. PubMed ID: 25303226
[TBL] [Abstract][Full Text] [Related]
39. Biased allosteric modulation of formyl peptide receptor 2 leads to distinct receptor conformational states for pro- and anti-inflammatory signaling.
Zhang S; Gong H; Ge Y; Ye RD
Pharmacol Res; 2020 Nov; 161():105117. PubMed ID: 32768626
[TBL] [Abstract][Full Text] [Related]
40. The formyl peptide fMLF primes platelet activation and augments thrombus formation.
Salamah MF; Ravishankar D; Vaiyapuri R; Moraes LA; Patel K; Perretti M; Gibbins JM; Vaiyapuri S
J Thromb Haemost; 2019 Jul; 17(7):1120-1133. PubMed ID: 31033193
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]