206 related articles for article (PubMed ID: 19916559)
1. The MDM2-binding region in the transactivation domain of p53 also acts as a Bcl-X(L)-binding motif.
Xu H; Ye H; Osman NE; Sadler K; Won EY; Chi SW; Yoon HS
Biochemistry; 2009 Dec; 48(51):12159-68. PubMed ID: 19916559
[TBL] [Abstract][Full Text] [Related]
2. Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins.
Lee MS; Ha JH; Yoon HS; Lee CK; Chi SW
Biochem Biophys Res Commun; 2014 Feb; 445(1):120-5. PubMed ID: 24491548
[TBL] [Abstract][Full Text] [Related]
3. Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.
Ha JH; Shin JS; Yoon MK; Lee MS; He F; Bae KH; Yoon HS; Lee CK; Park SG; Muto Y; Chi SW
J Biol Chem; 2013 Mar; 288(10):7387-98. PubMed ID: 23316052
[TBL] [Abstract][Full Text] [Related]
4. Targeting of p53 peptide analogues to anti-apoptotic Bcl-2 family proteins as revealed by NMR spectroscopy.
Shin JS; Ha JH; Chi SW
Biochem Biophys Res Commun; 2014 Jan; 443(3):882-7. PubMed ID: 24342622
[TBL] [Abstract][Full Text] [Related]
5. Molecular mimicry-based repositioning of nutlin-3 to anti-apoptotic Bcl-2 family proteins.
Ha JH; Won EY; Shin JS; Jang M; Ryu KS; Bae KH; Park SG; Park BC; Yoon HS; Chi SW
J Am Chem Soc; 2011 Feb; 133(5):1244-7. PubMed ID: 21210687
[TBL] [Abstract][Full Text] [Related]
6. Molecular basis of Bcl-X(L)-p53 interaction: insights from molecular dynamics simulations.
Bharatham N; Chi SW; Yoon HS
PLoS One; 2011; 6(10):e26014. PubMed ID: 22039431
[TBL] [Abstract][Full Text] [Related]
7. The N-terminal domain of tumor suppressor p53 is involved in the molecular interaction with the anti-apoptotic protein Bcl-Xl.
Xu H; Tai J; Ye H; Kang CB; Yoon HS
Biochem Biophys Res Commun; 2006 Mar; 341(4):938-44. PubMed ID: 16455050
[TBL] [Abstract][Full Text] [Related]
8. Defining the p53 DNA-binding domain/Bcl-x(L)-binding interface using NMR.
Petros AM; Gunasekera A; Xu N; Olejniczak ET; Fesik SW
FEBS Lett; 2004 Feb; 559(1-3):171-4. PubMed ID: 14960327
[TBL] [Abstract][Full Text] [Related]
9. Anti-apoptosis proteins Mcl-1 and Bcl-xL have different p53-binding profiles.
Yao H; Mi S; Gong W; Lin J; Xu N; Perrett S; Xia B; Wang J; Feng Y
Biochemistry; 2013 Sep; 52(37):6324-34. PubMed ID: 23977882
[TBL] [Abstract][Full Text] [Related]
10. Determinants of specificity of MDM2 for the activation domains of p53 and p65: proline27 disrupts the MDM2-binding motif of p53.
Zondlo SC; Lee AE; Zondlo NJ
Biochemistry; 2006 Oct; 45(39):11945-57. PubMed ID: 17002294
[TBL] [Abstract][Full Text] [Related]
11. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Kussie PH; Gorina S; Marechal V; Elenbaas B; Moreau J; Levine AJ; Pavletich NP
Science; 1996 Nov; 274(5289):948-53. PubMed ID: 8875929
[TBL] [Abstract][Full Text] [Related]
12. Effect of HA14-1 on apoptosis-regulating proteins in HeLa cells.
Rehman K; Tariq M; Akash MS; Gillani Z; Qazi MH
Chem Biol Drug Des; 2014 Mar; 83(3):317-23. PubMed ID: 24118733
[TBL] [Abstract][Full Text] [Related]
13. Competitive binding between dynamic p53 transactivation subdomains to human MDM2 protein: implications for regulating the p53·MDM2/MDMX interaction.
Shan B; Li DW; Brüschweiler-Li L; Brüschweiler R
J Biol Chem; 2012 Aug; 287(36):30376-84. PubMed ID: 22807444
[TBL] [Abstract][Full Text] [Related]
14. Anti-apoptotic Bcl-XL protein in complex with BH3 peptides of pro-apoptotic Bak, Bad, and Bim proteins: comparative molecular dynamics simulations.
Lama D; Sankararamakrishnan R
Proteins; 2008 Nov; 73(2):492-514. PubMed ID: 18452209
[TBL] [Abstract][Full Text] [Related]
15. A conserved hydrophobic core at Bcl-xL mediates its structural stability and binding affinity with BH3-domain peptide of pro-apoptotic protein.
Feng Y; Zhang L; Hu T; Shen X; Ding J; Chen K; Jiang H; Liu D
Arch Biochem Biophys; 2009 Apr; 484(1):46-54. PubMed ID: 19161970
[TBL] [Abstract][Full Text] [Related]
16. p53 Phosphomimetics Preserve Transient Secondary Structure but Reduce Binding to Mdm2 and MdmX.
Levy R; Gregory E; Borcherds W; Daughdrill G
Biomolecules; 2019 Mar; 9(3):. PubMed ID: 30832340
[TBL] [Abstract][Full Text] [Related]
17. Structural details on mdm2-p53 interaction.
Chi SW; Lee SH; Kim DH; Ahn MJ; Kim JS; Woo JY; Torizawa T; Kainosho M; Han KH
J Biol Chem; 2005 Nov; 280(46):38795-802. PubMed ID: 16159876
[TBL] [Abstract][Full Text] [Related]
18. Conservation of Affinity Rather Than Sequence Underlies a Dynamic Evolution of the Motif-Mediated p53/MDM2 Interaction in Ray-Finned Fishes.
Mihalič F; Arcila D; Pettersson ME; Farkhondehkish P; Andersson E; Andersson L; Betancur-R R; Jemth P
Mol Biol Evol; 2024 Feb; 41(2):. PubMed ID: 38301272
[TBL] [Abstract][Full Text] [Related]
19. Molecular recognition of p53 and MDM2 by USP7/HAUSP.
Sheng Y; Saridakis V; Sarkari F; Duan S; Wu T; Arrowsmith CH; Frappier L
Nat Struct Mol Biol; 2006 Mar; 13(3):285-91. PubMed ID: 16474402
[TBL] [Abstract][Full Text] [Related]
20. Impact of the K24N mutation on the transactivation domain of p53 and its binding to murine double-minute clone 2.
Zhan YA; Wu H; Powell AT; Daughdrill GW; Ytreberg FM
Proteins; 2013 Oct; 81(10):1738-47. PubMed ID: 23609977
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
