397 related articles for article (PubMed ID: 19917253)
1. Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling.
Gao S; Alarcón C; Sapkota G; Rahman S; Chen PY; Goerner N; Macias MJ; Erdjument-Bromage H; Tempst P; Massagué J
Mol Cell; 2009 Nov; 36(3):457-68. PubMed ID: 19917253
[TBL] [Abstract][Full Text] [Related]
2. NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor.
Kuratomi G; Komuro A; Goto K; Shinozaki M; Miyazawa K; Miyazono K; Imamura T
Biochem J; 2005 Mar; 386(Pt 3):461-70. PubMed ID: 15496141
[TBL] [Abstract][Full Text] [Related]
3. Smad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.
Yan X; Liao H; Cheng M; Shi X; Lin X; Feng XH; Chen YG
J Biol Chem; 2016 Jan; 291(1):382-92. PubMed ID: 26555259
[TBL] [Abstract][Full Text] [Related]
4. Phospho-Smad1 modulation by nedd4 E3 ligase in BMP/TGF-β signaling.
Kim BG; Lee JH; Yasuda J; Ryoo HM; Cho JY
J Bone Miner Res; 2011 Jul; 26(7):1411-24. PubMed ID: 21308777
[TBL] [Abstract][Full Text] [Related]
5. Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins.
Nakano A; Koinuma D; Miyazawa K; Uchida T; Saitoh M; Kawabata M; Hanai J; Akiyama H; Abe M; Miyazono K; Matsumoto T; Imamura T
J Biol Chem; 2009 Mar; 284(10):6109-15. PubMed ID: 19122240
[TBL] [Abstract][Full Text] [Related]
6. Selective targeting of activating and inhibitory Smads by distinct WWP2 ubiquitin ligase isoforms differentially modulates TGFβ signalling and EMT.
Soond SM; Chantry A
Oncogene; 2011 May; 30(21):2451-62. PubMed ID: 21258410
[TBL] [Abstract][Full Text] [Related]
7. The phosphorylation of the Smad2/3 linker region by nemo-like kinase regulates TGF-β signaling.
Liang J; Zhou Y; Zhang N; Wang D; Cheng X; Li K; Huang R; Lu Y; Wang H; Han D; Wu W; Han M; Miao S; Wang L; Zhao H; Song W
J Biol Chem; 2021; 296():100512. PubMed ID: 33676893
[TBL] [Abstract][Full Text] [Related]
8. Diminution of microRNA-98 alleviates renal fibrosis in diabetic nephropathy by elevating Nedd4L and inactivating TGF-β/Smad2/3 pathway.
Zeng Y; Feng Z; Liao Y; Yang M; Bai Y; He Z
Cell Cycle; 2020 Dec; 19(24):3406-3418. PubMed ID: 33315506
[TBL] [Abstract][Full Text] [Related]
9. Degradation of the tumor suppressor Smad4 by WW and HECT domain ubiquitin ligases.
Morén A; Imamura T; Miyazono K; Heldin CH; Moustakas A
J Biol Chem; 2005 Jun; 280(23):22115-23. PubMed ID: 15817471
[TBL] [Abstract][Full Text] [Related]
10. CUL4B, NEDD4, and UGT1As involve in the TGF-β signalling in hepatocellular carcinoma.
Qu Z; Li D; Xu H; Zhang R; Li B; Sun C; Dong W; Zhang Y
Ann Hepatol; 2016; 15(4):568-76. PubMed ID: 27236156
[TBL] [Abstract][Full Text] [Related]
11. A Smad action turnover switch operated by WW domain readers of a phosphoserine code.
Aragón E; Goerner N; Zaromytidou AI; Xi Q; Escobedo A; Massagué J; Macias MJ
Genes Dev; 2011 Jun; 25(12):1275-88. PubMed ID: 21685363
[TBL] [Abstract][Full Text] [Related]
12. miR-93 promotes TGF-β-induced epithelial-to-mesenchymal transition through downregulation of NEDD4L in lung cancer cells.
Qu MH; Han C; Srivastava AK; Cui T; Zou N; Gao ZQ; Wang QE
Tumour Biol; 2016 Apr; 37(4):5645-51. PubMed ID: 26581907
[TBL] [Abstract][Full Text] [Related]
13. Smad2 is essential for maintenance of the human and mouse primed pluripotent stem cell state.
Sakaki-Yumoto M; Liu J; Ramalho-Santos M; Yoshida N; Derynck R
J Biol Chem; 2013 Jun; 288(25):18546-60. PubMed ID: 23649632
[TBL] [Abstract][Full Text] [Related]
14. Transforming growth factor-β signalling: role and consequences of Smad linker region phosphorylation.
Kamato D; Burch ML; Piva TJ; Rezaei HB; Rostam MA; Xu S; Zheng W; Little PJ; Osman N
Cell Signal; 2013 Oct; 25(10):2017-24. PubMed ID: 23770288
[TBL] [Abstract][Full Text] [Related]
15. DDB2 modulates TGF-β signal transduction in human ovarian cancer cells by downregulating NEDD4L.
Zhao R; Cui T; Han C; Zhang X; He J; Srivastava AK; Yu J; Wani AA; Wang QE
Nucleic Acids Res; 2015 Sep; 43(16):7838-49. PubMed ID: 26130719
[TBL] [Abstract][Full Text] [Related]
16. Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.
Chandran S; Li H; Dong W; Krasinska K; Adams C; Alexandrova L; Chien A; Hallows KR; Bhalla V
J Biol Chem; 2011 Oct; 286(43):37830-40. PubMed ID: 21900244
[TBL] [Abstract][Full Text] [Related]
17. C18 ORF1, a novel negative regulator of transforming growth factor-β signaling.
Nakano N; Maeyama K; Sakata N; Itoh F; Akatsu R; Nakata M; Katsu Y; Ikeno S; Togawa Y; Vo Nguyen TT; Watanabe Y; Kato M; Itoh S
J Biol Chem; 2014 May; 289(18):12680-92. PubMed ID: 24627487
[TBL] [Abstract][Full Text] [Related]
18. The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation.
Seo SR; Lallemand F; Ferrand N; Pessah M; L'Hoste S; Camonis J; Atfi A
EMBO J; 2004 Oct; 23(19):3780-92. PubMed ID: 15359284
[TBL] [Abstract][Full Text] [Related]
19. Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-beta signaling.
Wrighton KH; Willis D; Long J; Liu F; Lin X; Feng XH
J Biol Chem; 2006 Dec; 281(50):38365-75. PubMed ID: 17035229
[TBL] [Abstract][Full Text] [Related]
20. Genetic variations in the sodium balance-regulating genes ENaC, NEDD4L, NDFIP2 and USP2 influence blood pressure and hypertension.
Jin HS; Hong KW; Lim JE; Hwang SY; Lee SH; Shin C; Park HK; Oh B
Kidney Blood Press Res; 2010; 33(1):15-23. PubMed ID: 20090362
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
