BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 19917720)

  • 1. Cyclin-dependent kinase 1-mediated Bcl-xL/Bcl-2 phosphorylation acts as a functional link coupling mitotic arrest and apoptosis.
    Terrano DT; Upreti M; Chambers TC
    Mol Cell Biol; 2010 Feb; 30(3):640-56. PubMed ID: 19917720
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cyclin-dependent kinase-1 (Cdk1)/cyclin B1 dictates cell fate after mitotic arrest via phosphoregulation of antiapoptotic Bcl-2 proteins.
    Sakurikar N; Eichhorn JM; Chambers TC
    J Biol Chem; 2012 Nov; 287(46):39193-204. PubMed ID: 22965228
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-X
    Choi HJ; Zhu BT
    Steroids; 2019 Oct; 150():108381. PubMed ID: 30797877
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest.
    Choi HJ; Zhu BT
    Mol Carcinog; 2014 Feb; 53(2):125-37. PubMed ID: 22949227
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Temporal relationship of CDK1 activation and mitotic arrest to cytosolic accumulation of cytochrome C and caspase-3 activity during Taxol-induced apoptosis of human AML HL-60 cells.
    Ibrado AM; Kim CN; Bhalla K
    Leukemia; 1998 Dec; 12(12):1930-6. PubMed ID: 9844922
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK1 switches mitotic arrest to apoptosis by phosphorylating Bcl-2/Bax family proteins during treatment with microtubule interfering agents.
    Zhou L; Cai X; Han X; Xu N; Chang DC
    Cell Biol Int; 2014 Jun; 38(6):737-46. PubMed ID: 24677263
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis.
    Mac Fhearraigh S; Mc Gee MM
    Cell Cycle; 2011 Nov; 10(22):3886-96. PubMed ID: 22071694
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phospho-Bcl-x(L)(Ser62) plays a key role at DNA damage-induced G(2) checkpoint.
    Wang J; Beauchemin M; Bertrand R
    Cell Cycle; 2012 Jun; 11(11):2159-69. PubMed ID: 22617334
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Bcl-xL controls a switch between cell death modes during mitotic arrest.
    Bah N; Maillet L; Ryan J; Dubreil S; Gautier F; Letai A; Juin P; Barillé-Nion S
    Cell Death Dis; 2014 Jun; 5(6):e1291. PubMed ID: 24922075
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Phosphorylation of Bcl-2 in G2/M phase-arrested cells following photodynamic therapy with hypericin involves a CDK1-mediated signal and delays the onset of apoptosis.
    Vantieghem A; Xu Y; Assefa Z; Piette J; Vandenheede JR; Merlevede W; De Witte PA; Agostinis P
    J Biol Chem; 2002 Oct; 277(40):37718-31. PubMed ID: 12101183
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phospho-Bcl-xL(Ser62) influences spindle assembly and chromosome segregation during mitosis.
    Wang J; Beauchemin M; Bertrand R
    Cell Cycle; 2014; 13(8):1313-26. PubMed ID: 24621501
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1.
    Chang LC; Yu YL; Liu CY; Cheng YY; Chou RH; Hsieh MT; Lin HY; Hung HY; Huang LJ; Wu YC; Kuo SC
    Cancer Chemother Pharmacol; 2015 Jun; 75(6):1303-15. PubMed ID: 25947085
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a novel Bax-Cdk1 signalling complex that links activation of the mitotic checkpoint to apoptosis.
    Darweesh O; Al-Shehri E; Falquez H; Lauterwasser J; Edlich F; Patel R
    J Cell Sci; 2021 Apr; 134(8):. PubMed ID: 33722980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MJ-29 inhibits tubulin polymerization, induces mitotic arrest, and triggers apoptosis via cyclin-dependent kinase 1-mediated Bcl-2 phosphorylation in human leukemia U937 cells.
    Yang JS; Hour MJ; Huang WW; Lin KL; Kuo SC; Chung JG
    J Pharmacol Exp Ther; 2010 Aug; 334(2):477-88. PubMed ID: 20463006
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cdk1/cyclin B plays a key role in mitotic arrest-induced apoptosis by phosphorylation of Mcl-1, promoting its degradation and freeing Bak from sequestration.
    Chu R; Terrano DT; Chambers TC
    Biochem Pharmacol; 2012 Jan; 83(2):199-206. PubMed ID: 22024133
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation of Bcl-2 is a marker of M phase events and not a determinant of apoptosis.
    Ling YH; Tornos C; Perez-Soler R
    J Biol Chem; 1998 Jul; 273(30):18984-91. PubMed ID: 9668078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest.
    Harley ME; Allan LA; Sanderson HS; Clarke PR
    EMBO J; 2010 Jul; 29(14):2407-20. PubMed ID: 20526282
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mechanisms of mitotic cell death induced by chemotherapy-mediated G2 checkpoint abrogation.
    Vogel C; Hager C; Bastians H
    Cancer Res; 2007 Jan; 67(1):339-45. PubMed ID: 17210716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitotic phosphorylation of Bcl-2 during normal cell cycle progression and Taxol-induced growth arrest.
    Scatena CD; Stewart ZA; Mays D; Tang LJ; Keefer CJ; Leach SD; Pietenpol JA
    J Biol Chem; 1998 Nov; 273(46):30777-84. PubMed ID: 9804855
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
    Castedo M; Perfettini JL; Roumier T; Yakushijin K; Horne D; Medema R; Kroemer G
    Oncogene; 2004 May; 23(25):4353-61. PubMed ID: 15048074
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.