BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 19923742)

  • 1. Purification, crystallization and preliminary X-ray diffraction analysis of disease-related mutants of p97.
    Tang WK; Li D; Esser L; Xia D
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2009 Nov; 65(Pt 11):1166-70. PubMed ID: 19923742
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A unique IBMPFD-related P97/VCP mutation with differential binding pattern and subcellular localization.
    Erzurumlu Y; Kose FA; Gozen O; Gozuacik D; Toth EA; Ballar P
    Int J Biochem Cell Biol; 2013 Apr; 45(4):773-82. PubMed ID: 23333620
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants.
    Tang WK; Li D; Li CC; Esser L; Dai R; Guo L; Xia D
    EMBO J; 2010 Jul; 29(13):2217-29. PubMed ID: 20512113
    [TBL] [Abstract][Full Text] [Related]  

  • 4. IBMPFD Disease-Causing Mutant VCP/p97 Proteins Are Targets of Autophagic-Lysosomal Degradation.
    Bayraktar O; Oral O; Kocaturk NM; Akkoc Y; Eberhart K; Kosar A; Gozuacik D
    PLoS One; 2016; 11(10):e0164864. PubMed ID: 27768726
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy.
    Ju JS; Weihl CC
    Hum Mol Genet; 2010 Apr; 19(R1):R38-45. PubMed ID: 20410287
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation.
    Weihl CC; Dalal S; Pestronk A; Hanson PI
    Hum Mol Genet; 2006 Jan; 15(2):189-99. PubMed ID: 16321991
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and functional deviations in disease-associated p97 mutants.
    Tang WK; Xia D
    J Struct Biol; 2012 Aug; 179(2):83-92. PubMed ID: 22579784
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
    Custer SK; Neumann M; Lu H; Wright AC; Taylor JP
    Hum Mol Genet; 2010 May; 19(9):1741-55. PubMed ID: 20147319
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Imbalances in p97 co-factor interactions in human proteinopathy.
    Fernández-Sáiz V; Buchberger A
    EMBO Rep; 2010 Jun; 11(6):479-85. PubMed ID: 20414249
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered intersubunit communication is the molecular basis for functional defects of pathogenic p97 mutants.
    Tang WK; Xia D
    J Biol Chem; 2013 Dec; 288(51):36624-35. PubMed ID: 24196964
    [TBL] [Abstract][Full Text] [Related]  

  • 11. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD.
    Tresse E; Salomons FA; Vesa J; Bott LC; Kimonis V; Yao TP; Dantuma NP; Taylor JP
    Autophagy; 2010 Feb; 6(2):217-27. PubMed ID: 20104022
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.
    Niwa H; Ewens CA; Tsang C; Yeung HO; Zhang X; Freemont PS
    J Biol Chem; 2012 Mar; 287(11):8561-70. PubMed ID: 22270372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model.
    Chang YC; Hung WT; Chang YC; Chang HC; Wu CL; Chiang AS; Jackson GR; Sang TK
    PLoS Genet; 2011 Feb; 7(2):e1001288. PubMed ID: 21304887
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The multiple faces of valosin-containing protein-associated diseases: inclusion body myopathy with Paget's disease of bone, frontotemporal dementia, and amyotrophic lateral sclerosis.
    Nalbandian A; Donkervoort S; Dec E; Badadani M; Katheria V; Rana P; Nguyen C; Mukherjee J; Caiozzo V; Martin B; Watts GD; Vesa J; Smith C; Kimonis VE
    J Mol Neurosci; 2011 Nov; 45(3):522-31. PubMed ID: 21892620
    [TBL] [Abstract][Full Text] [Related]  

  • 15. VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation.
    Li H; Cui Y; Wei J; Liu C; Chen Y; Cui CP; Li L; Zhang X; Zhang L
    FASEB J; 2019 Feb; 33(2):2928-2943. PubMed ID: 30335548
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The homozygote VCP(R¹⁵⁵H/R¹⁵⁵H) mouse model exhibits accelerated human VCP-associated disease pathology.
    Nalbandian A; Llewellyn KJ; Kitazawa M; Yin HZ; Badadani M; Khanlou N; Edwards R; Nguyen C; Mukherjee J; Mozaffar T; Watts G; Weiss J; Kimonis VE
    PLoS One; 2012; 7(9):e46308. PubMed ID: 23029473
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease.
    Ju JS; Fuentealba RA; Miller SE; Jackson E; Piwnica-Worms D; Baloh RH; Weihl CC
    J Cell Biol; 2009 Dec; 187(6):875-88. PubMed ID: 20008565
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy.
    Blythe EE; Olson KC; Chau V; Deshaies RJ
    Proc Natl Acad Sci U S A; 2017 May; 114(22):E4380-E4388. PubMed ID: 28512218
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Crystallization and preliminary X-ray crystallographic analysis of the N domain of p97/VCP in complex with the UBX domain of FAF1.
    Shin HY; Kang W; Lee SY; Yang JK
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2010 Jan; 66(Pt 1):41-3. PubMed ID: 20057067
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystallization and preliminary X-ray crystallographic analysis of the hexameric human p97/VCP ND1 fragment in complex with the UBX domain of human FAF1.
    Kang W; Yang JK
    Acta Crystallogr Sect F Struct Biol Cryst Commun; 2011 Oct; 67(Pt 10):1199-202. PubMed ID: 22102026
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.