388 related articles for article (PubMed ID: 19929853)
21. The low-affinity monocarboxylate transporter MCT4 is adapted to the export of lactate in highly glycolytic cells.
Dimmer KS; Friedrich B; Lang F; Deitmer JW; Bröer S
Biochem J; 2000 Aug; 350 Pt 1(Pt 1):219-27. PubMed ID: 10926847
[TBL] [Abstract][Full Text] [Related]
22. Activity of the monocarboxylate transporter 1 inhibitor AZD3965 in small cell lung cancer.
Polański R; Hodgkinson CL; Fusi A; Nonaka D; Priest L; Kelly P; Trapani F; Bishop PW; White A; Critchlow SE; Smith PD; Blackhall F; Dive C; Morrow CJ
Clin Cancer Res; 2014 Feb; 20(4):926-937. PubMed ID: 24277449
[TBL] [Abstract][Full Text] [Related]
23. The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
Nancolas B; Guo L; Zhou R; Nath K; Nelson DS; Leeper DB; Blair IA; Glickson JD; Halestrap AP
Biochem J; 2016 Apr; 473(7):929-36. PubMed ID: 26831515
[TBL] [Abstract][Full Text] [Related]
24. Monocarboxylate transporters 1 and 4: expression and regulation by PPARα in ovine ruminal epithelial cells.
Benesch F; Dengler F; Masur F; Pfannkuche H; Gäbel G
Am J Physiol Regul Integr Comp Physiol; 2014 Dec; 307(12):R1428-37. PubMed ID: 25320343
[TBL] [Abstract][Full Text] [Related]
25. The kinetics, substrate, and inhibitor specificity of the monocarboxylate (lactate) transporter of rat liver cells determined using the fluorescent intracellular pH indicator, 2',7'-bis(carboxyethyl)-5(6)-carboxyfluorescein.
Jackson VN; Halestrap AP
J Biol Chem; 1996 Jan; 271(2):861-8. PubMed ID: 8557697
[TBL] [Abstract][Full Text] [Related]
26. Targeting the monocarboxylate transporter MCT2 and lactate dehydrogenase A LDHA in cancer cells with FX-11 and AR-C155858 inhibitors.
Alobaidi B; Hashimi SM; Alqosaibi AI; AlQurashi N; Alhazmi S
Eur Rev Med Pharmacol Sci; 2023 Jul; 27(14):6605-6617. PubMed ID: 37522672
[TBL] [Abstract][Full Text] [Related]
27. Metabolic effects of blocking lactate transport in brain cortical tissue slices using an inhibitor specific to MCT1 and MCT2.
Rae C; Nasrallah FA; Bröer S
Neurochem Res; 2009 Oct; 34(10):1783-91. PubMed ID: 19404741
[TBL] [Abstract][Full Text] [Related]
28. Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Wang N; Jiang X; Zhang S; Zhu A; Yuan Y; Xu H; Lei J; Yan C
Cell; 2021 Jan; 184(2):370-383.e13. PubMed ID: 33333023
[TBL] [Abstract][Full Text] [Related]
29. A Nonradioactive High-Throughput Screening-Compatible Cell-Based Assay to Identify Inhibitors of the Monocarboxylate Transporter Protein 1.
Bailey TL; Nieto A; McDonald PH
Assay Drug Dev Technol; 2019 Aug; 17(6):275-284. PubMed ID: 31532712
[No Abstract] [Full Text] [Related]
30. Targeting Lactate Metabolism by Inhibiting MCT1 or MCT4 Impairs Leukemic Cell Proliferation, Induces Two Different Related Death-Pathways and Increases Chemotherapeutic Sensitivity of Acute Myeloid Leukemia Cells.
Saulle E; Spinello I; Quaranta MT; Pasquini L; Pelosi E; Iorio E; Castelli G; Chirico M; Pisanu ME; Ottone T; Voso MT; Testa U; Labbaye C
Front Oncol; 2020; 10():621458. PubMed ID: 33614502
[TBL] [Abstract][Full Text] [Related]
31. Role of monocarboxylate transporters in AMPK-mediated protection against excitotoxic injury in the rat retina.
Yamagishi H; Kirai N; Morita A; Kashihara T; Nakahara T
Eur J Pharmacol; 2024 May; 970():176510. PubMed ID: 38493917
[TBL] [Abstract][Full Text] [Related]
32. Helix 8 and helix 10 are involved in substrate recognition in the rat monocarboxylate transporter MCT1.
Rahman B; Schneider HP; Bröer A; Deitmer JW; Bröer S
Biochemistry; 1999 Aug; 38(35):11577-84. PubMed ID: 10471310
[TBL] [Abstract][Full Text] [Related]
33. Clinical significance of metabolism-related biomarkers in non-Hodgkin lymphoma - MCT1 as potential target in diffuse large B cell lymphoma.
Afonso J; Pinto T; Simões-Sousa S; Schmitt F; Longatto-Filho A; Pinheiro C; Marques H; Baltazar F
Cell Oncol (Dordr); 2019 Jun; 42(3):303-318. PubMed ID: 30790227
[TBL] [Abstract][Full Text] [Related]
34. MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4.
Hong CS; Graham NA; Gu W; Espindola Camacho C; Mah V; Maresh EL; Alavi M; Bagryanova L; Krotee PAL; Gardner BK; Behbahan IS; Horvath S; Chia D; Mellinghoff IK; Hurvitz SA; Dubinett SM; Critchlow SE; Kurdistani SK; Goodglick L; Braas D; Graeber TG; Christofk HR
Cell Rep; 2016 Feb; 14(7):1590-1601. PubMed ID: 26876179
[TBL] [Abstract][Full Text] [Related]
35. Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro.
Brandstetter G; Blatt S; Goldschmitt J; Taylor L; Heymann P; Al-Nawas B; Ziebart T
Clin Oral Investig; 2021 Jan; 25(1):295-310. PubMed ID: 32495222
[TBL] [Abstract][Full Text] [Related]
36. Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes.
Bröer S; Bröer A; Schneider HP; Stegen C; Halestrap AP; Deitmer JW
Biochem J; 1999 Aug; 341 ( Pt 3)(Pt 3):529-35. PubMed ID: 10417314
[TBL] [Abstract][Full Text] [Related]
37. Immunohistochemical analysis of MCT1, MCT2 and MCT4 expression in rat plantaris muscle.
Hashimoto T; Masuda S; Taguchi S; Brooks GA
J Physiol; 2005 Aug; 567(Pt 1):121-9. PubMed ID: 15932892
[TBL] [Abstract][Full Text] [Related]
38. Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes.
Pérez de Heredia F; Wood IS; Trayhurn P
Pflugers Arch; 2010 Feb; 459(3):509-18. PubMed ID: 19876643
[TBL] [Abstract][Full Text] [Related]
39. A Holistic Evolutionary and 3D Pharmacophore Modelling Study Provides Insights into the Metabolism, Function, and Substrate Selectivity of the Human Monocarboxylate Transporter 4 (hMCT4).
Papakonstantinou E; Vlachakis D; Thireou T; Vlachoyiannopoulos PG; Eliopoulos E
Int J Mol Sci; 2021 Mar; 22(6):. PubMed ID: 33805725
[TBL] [Abstract][Full Text] [Related]
40. In Vitro and In Vivo Efficacy of AZD3965 and Alpha-Cyano-4-Hydroxycinnamic Acid in the Murine 4T1 Breast Tumor Model.
Guan X; Morris ME
AAPS J; 2020 Jun; 22(4):84. PubMed ID: 32529599
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]