BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

429 related articles for article (PubMed ID: 19933576)

  • 1. Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes.
    Haque F; Mazzeo D; Patel JT; Smallwood DT; Ellis JA; Shanahan CM; Shackleton S
    J Biol Chem; 2010 Jan; 285(5):3487-98. PubMed ID: 19933576
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Contribution of SUN1 mutations to the pathomechanism in muscular dystrophies.
    Li P; Meinke P; Huong le TT; Wehnert M; Noegel AA
    Hum Mutat; 2014 Apr; 35(4):452-61. PubMed ID: 24375709
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Muscular dystrophy-associated SUN1 and SUN2 variants disrupt nuclear-cytoskeletal connections and myonuclear organization.
    Meinke P; Mattioli E; Haque F; Antoku S; Columbaro M; Straatman KR; Worman HJ; Gundersen GG; Lattanzi G; Wehnert M; Shackleton S
    PLoS Genet; 2014 Sep; 10(9):e1004605. PubMed ID: 25210889
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Accumulation of the inner nuclear envelope protein Sun1 is pathogenic in progeric and dystrophic laminopathies.
    Chen CY; Chi YH; Mutalif RA; Starost MF; Myers TG; Anderson SA; Stewart CL; Jeang KT
    Cell; 2012 Apr; 149(3):565-77. PubMed ID: 22541428
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LINC complex alterations in DMD and EDMD/CMT fibroblasts.
    Taranum S; Vaylann E; Meinke P; Abraham S; Yang L; Neumann S; Karakesisoglou I; Wehnert M; Noegel AA
    Eur J Cell Biol; 2012 Aug; 91(8):614-28. PubMed ID: 22555292
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prelamin A-mediated recruitment of SUN1 to the nuclear envelope directs nuclear positioning in human muscle.
    Mattioli E; Columbaro M; Capanni C; Maraldi NM; Cenni V; Scotlandi K; Marino MT; Merlini L; Squarzoni S; Lattanzi G
    Cell Death Differ; 2011 Aug; 18(8):1305-15. PubMed ID: 21311568
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response.
    Lei K; Zhu X; Xu R; Shao C; Xu T; Zhuang Y; Han M
    Curr Biol; 2012 Sep; 22(17):1609-15. PubMed ID: 22863315
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dysregulated interactions between lamin A and SUN1 induce abnormalities in the nuclear envelope and endoplasmic reticulum in progeric laminopathies.
    Chen ZJ; Wang WP; Chen YC; Wang JY; Lin WH; Tai LA; Liou GG; Yang CS; Chi YH
    J Cell Sci; 2014 Apr; 127(Pt 8):1792-804. PubMed ID: 24522183
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mitotic phosphorylation of SUN1 loosens its connection with the nuclear lamina while the LINC complex remains intact.
    Patel JT; Bottrill A; Prosser SL; Jayaraman S; Straatman K; Fry AM; Shackleton S
    Nucleus; 2014; 5(5):462-73. PubMed ID: 25482198
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imbalanced nucleocytoskeletal connections create common polarity defects in progeria and physiological aging.
    Chang W; Wang Y; Luxton GWG; Östlund C; Worman HJ; Gundersen GG
    Proc Natl Acad Sci U S A; 2019 Feb; 116(9):3578-3583. PubMed ID: 30808750
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.
    Haque F; Lloyd DJ; Smallwood DT; Dent CL; Shanahan CM; Fry AM; Trembath RC; Shackleton S
    Mol Cell Biol; 2006 May; 26(10):3738-51. PubMed ID: 16648470
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin-2 in breast cancer.
    Matsumoto A; Hieda M; Yokoyama Y; Nishioka Y; Yoshidome K; Tsujimoto M; Matsuura N
    Cancer Med; 2015 Oct; 4(10):1547-57. PubMed ID: 26175118
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.
    Zhang Q; Bethmann C; Worth NF; Davies JD; Wasner C; Feuer A; Ragnauth CD; Yi Q; Mellad JA; Warren DT; Wheeler MA; Ellis JA; Skepper JN; Vorgerd M; Schlotter-Weigel B; Weissberg PL; Roberts RG; Wehnert M; Shanahan CM
    Hum Mol Genet; 2007 Dec; 16(23):2816-33. PubMed ID: 17761684
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reversal of laminopathies: the curious case of SUN1.
    Chi YH; Chen CY; Jeang KT
    Nucleus; 2012; 3(5):418-21. PubMed ID: 22895095
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins.
    Ostlund C; Folker ES; Choi JC; Gomes ER; Gundersen GG; Worman HJ
    J Cell Sci; 2009 Nov; 122(Pt 22):4099-108. PubMed ID: 19843581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dysfunctional connections between the nucleus and the actin and microtubule networks in laminopathic models.
    Hale CM; Shrestha AL; Khatau SB; Stewart-Hutchinson PJ; Hernandez L; Stewart CL; Hodzic D; Wirtz D
    Biophys J; 2008 Dec; 95(11):5462-75. PubMed ID: 18790843
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The LINC complex and human disease.
    Meinke P; Nguyen TD; Wehnert MS
    Biochem Soc Trans; 2011 Dec; 39(6):1693-7. PubMed ID: 22103509
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component.
    Jungwirth MT; Kumar D; Jeong DY; Goodchild RE
    BMC Cell Biol; 2011 May; 12():24. PubMed ID: 21627841
    [TBL] [Abstract][Full Text] [Related]  

  • 19. FHL1B Interacts with Lamin A/C and Emerin at the Nuclear Lamina and is Misregulated in Emery-Dreifuss Muscular Dystrophy.
    Ziat E; Mamchaoui K; Beuvin M; Nelson I; Azibani F; Spuler S; Bonne G; Bertrand AT
    J Neuromuscul Dis; 2016 Nov; 3(4):497-510. PubMed ID: 27911330
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of pathogenic mis-sense mutations in lamin A on its interaction with emerin in vivo.
    Holt I; Ostlund C; Stewart CL; Man Nt; Worman HJ; Morris GE
    J Cell Sci; 2003 Jul; 116(Pt 14):3027-35. PubMed ID: 12783988
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.