BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

327 related articles for article (PubMed ID: 19933846)

  • 1. Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling.
    Ritt DA; Monson DM; Specht SI; Morrison DK
    Mol Cell Biol; 2010 Feb; 30(3):806-19. PubMed ID: 19933846
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Regulation and role of Raf-1/B-Raf heterodimerization.
    Rushworth LK; Hindley AD; O'Neill E; Kolch W
    Mol Cell Biol; 2006 Mar; 26(6):2262-72. PubMed ID: 16508002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of Raf-1 by direct feedback phosphorylation.
    Dougherty MK; Müller J; Ritt DA; Zhou M; Zhou XZ; Copeland TD; Conrads TP; Veenstra TD; Lu KP; Morrison DK
    Mol Cell; 2005 Jan; 17(2):215-24. PubMed ID: 15664191
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.
    Li Y; Takahashi M; Stork PJS
    J Biol Chem; 2013 Sep; 288(38):27646-27657. PubMed ID: 23893412
    [TBL] [Abstract][Full Text] [Related]  

  • 5. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA; DeNicola GM; Winter SP; Tuveson DA
    Mol Cell; 2009 Nov; 36(3):477-86. PubMed ID: 19917255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced inhibition of ERK signaling by a novel allosteric MEK inhibitor, CH5126766, that suppresses feedback reactivation of RAF activity.
    Ishii N; Harada N; Joseph EW; Ohara K; Miura T; Sakamoto H; Matsuda Y; Tomii Y; Tachibana-Kondo Y; Iikura H; Aoki T; Shimma N; Arisawa M; Sowa Y; Poulikakos PI; Rosen N; Aoki Y; Sakai T
    Cancer Res; 2013 Jul; 73(13):4050-4060. PubMed ID: 23667175
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of novel in vivo Raf-1 phosphorylation sites mediating positive feedback Raf-1 regulation by extracellular signal-regulated kinase.
    Balan V; Leicht DT; Zhu J; Balan K; Kaplun A; Singh-Gupta V; Qin J; Ruan H; Comb MJ; Tzivion G
    Mol Biol Cell; 2006 Mar; 17(3):1141-53. PubMed ID: 16407412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Negative feedback regulation of Raf/MEK/ERK cascade after sublethal cerebral ischemia in the rat hippocampus.
    Cao Q; Qian M; Wang XF; Wang B; Wu HW; Zhu XJ; Wang YW; Guo J
    Neurochem Res; 2011 Jan; 36(1):153-62. PubMed ID: 20953701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Different effects of point mutations within the B-Raf glycine-rich loop in colorectal tumors on mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase and nuclear factor kappaB pathway and cellular transformation.
    Ikenoue T; Hikiba Y; Kanai F; Aragaki J; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2004 May; 64(10):3428-35. PubMed ID: 15150094
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Functional analysis of mutations within the kinase activation segment of B-Raf in human colorectal tumors.
    Ikenoue T; Hikiba Y; Kanai F; Tanaka Y; Imamura J; Imamura T; Ohta M; Ijichi H; Tateishi K; Kawakami T; Aragaki J; Matsumura M; Kawabe T; Omata M
    Cancer Res; 2003 Dec; 63(23):8132-7. PubMed ID: 14678966
    [TBL] [Abstract][Full Text] [Related]  

  • 11. RAF protein-serine/threonine kinases: structure and regulation.
    Roskoski R
    Biochem Biophys Res Commun; 2010 Aug; 399(3):313-7. PubMed ID: 20674547
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional interactions of Raf and MEK with Jun-N-terminal kinase (JNK) result in a positive feedback loop on the oncogenic Ras signaling pathway.
    Adler V; Qu Y; Smith SJ; Izotova L; Pestka S; Kung HF; Lin M; Friedman FK; Chie L; Chung D; Boutjdir M; Pincus MR
    Biochemistry; 2005 Aug; 44(32):10784-95. PubMed ID: 16086581
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.
    Li X; Jiang Y; Meisenhelder J; Yang W; Hawke DH; Zheng Y; Xia Y; Aldape K; He J; Hunter T; Wang L; Lu Z
    Mol Cell; 2016 Mar; 61(5):705-719. PubMed ID: 26942675
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
    Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
    Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting mitogen-activated protein kinase/extracellular signal-regulated kinase kinase in the mutant (V600E) B-Raf signaling cascade effectively inhibits melanoma lung metastases.
    Sharma A; Tran MA; Liang S; Sharma AK; Amin S; Smith CD; Dong C; Robertson GP
    Cancer Res; 2006 Aug; 66(16):8200-9. PubMed ID: 16912199
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Diacylglycerol kinase eta augments C-Raf activity and B-Raf/C-Raf heterodimerization.
    Yasuda S; Kai M; Imai S; Takeishi K; Taketomi A; Toyota M; Kanoh H; Sakane F
    J Biol Chem; 2009 Oct; 284(43):29559-70. PubMed ID: 19710016
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Two transforming C-RAF germ-line mutations identified in patients with therapy-related acute myeloid leukemia.
    Zebisch A; Staber PB; Delavar A; Bodner C; Hiden K; Fischereder K; Janakiraman M; Linkesch W; Auner HW; Emberger W; Windpassinger C; Schimek MG; Hoefler G; Troppmair J; Sill H
    Cancer Res; 2006 Apr; 66(7):3401-8. PubMed ID: 16585161
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins.
    Rudrabhatla P; Albers W; Pant HC
    J Neurosci; 2009 Nov; 29(47):14869-80. PubMed ID: 19940183
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover.
    Lim JH; Liu Y; Reineke E; Kao HY
    J Biol Chem; 2011 Dec; 286(52):44403-11. PubMed ID: 22033920
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.
    Chadee DN; Xu D; Hung G; Andalibi A; Lim DJ; Luo Z; Gutmann DH; Kyriakis JM
    Proc Natl Acad Sci U S A; 2006 Mar; 103(12):4463-8. PubMed ID: 16537381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.