205 related articles for article (PubMed ID: 19944078)
21. Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs.
Hikishima S; Hashimoto M; Magnowska L; Bzowska A; Yokomatsu T
Bioorg Med Chem; 2010 Mar; 18(6):2275-2284. PubMed ID: 20189401
[TBL] [Abstract][Full Text] [Related]
22. Remote mutations alter transition-state structure of human purine nucleoside phosphorylase.
Luo M; Li L; Schramm VL
Biochemistry; 2008 Feb; 47(8):2565-76. PubMed ID: 18281957
[TBL] [Abstract][Full Text] [Related]
23. Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase.
Lewandowicz A; Shi W; Evans GB; Tyler PC; Furneaux RH; Basso LA; Santos DS; Almo SC; Schramm VL
Biochemistry; 2003 May; 42(20):6057-66. PubMed ID: 12755607
[TBL] [Abstract][Full Text] [Related]
24. Crystal structure of the ternary complex of E. coli purine nucleoside phosphorylase with formycin B, a structural analogue of the substrate inosine, and phosphate (Sulphate) at 2.1 A resolution.
Koellner G; Luić M; Shugar D; Saenger W; Bzowska A
J Mol Biol; 1998 Jul; 280(1):153-66. PubMed ID: 9653038
[TBL] [Abstract][Full Text] [Related]
25. Antiproliferative activity of purine nucleoside phosphorylase multisubstrate analogue inhibitors containing difluoromethylene phosphonic acid against leukaemia and lymphoma cells.
Glavas-Obrovac L; Suver M; Hikishima S; Hashimoto M; Yokomatsu T; Magnowska L; Bzowska A
Chem Biol Drug Des; 2010 Apr; 75(4):392-9. PubMed ID: 20102369
[TBL] [Abstract][Full Text] [Related]
26. Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase.
Antosiewicz J; Wielgus-Kutrowska B; Długosz M; Holy A; Bzowska A
Nucleosides Nucleotides Nucleic Acids; 2007; 26(8-9):969-74. PubMed ID: 18058519
[TBL] [Abstract][Full Text] [Related]
27. Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.
Fedorov A; Shi W; Kicska G; Fedorov E; Tyler PC; Furneaux RH; Hanson JC; Gainsford GJ; Larese JZ; Schramm VL; Almo SC
Biochemistry; 2001 Jan; 40(4):853-60. PubMed ID: 11170405
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors.
Hikishima S; Isobe M; Koyanagi S; Soeda S; Shimeno H; Shibuya S; Yokomatsu T
Bioorg Med Chem; 2006 Mar; 14(5):1660-70. PubMed ID: 16263289
[TBL] [Abstract][Full Text] [Related]
29. Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism.
Koellner G; Bzowska A; Wielgus-Kutrowska B; Luić M; Steiner T; Saenger W; Stepiński J
J Mol Biol; 2002 Jan; 315(3):351-71. PubMed ID: 11786017
[TBL] [Abstract][Full Text] [Related]
30. Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene.
Dandanell G; Szczepanowski RH; Kierdaszuk B; Shugar D; Bochtler M
J Mol Biol; 2005 Apr; 348(1):113-25. PubMed ID: 15808857
[TBL] [Abstract][Full Text] [Related]
31. Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus.
Tahirov TH; Inagaki E; Ohshima N; Kitao T; Kuroishi C; Ukita Y; Takio K; Kobayashi M; Kuramitsu S; Yokoyama S; Miyano M
J Mol Biol; 2004 Apr; 337(5):1149-60. PubMed ID: 15046984
[TBL] [Abstract][Full Text] [Related]
32. Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state.
Wielgus-Kutrowska B; Breer K; Hashimoto M; Hikishima S; Yokomatsu T; Narczyk M; Dyzma A; Girstun A; Staroń K; Bzowska A
Bioorg Med Chem; 2012 Nov; 20(22):6758-69. PubMed ID: 23040896
[TBL] [Abstract][Full Text] [Related]
33. Acyclic ribooxacarbenium ion mimics as transition state analogues of human and malarial purine nucleoside phosphorylases.
Taylor EA; Clinch K; Kelly PM; Li L; Evans GB; Tyler PC; Schramm VL
J Am Chem Soc; 2007 Jun; 129(22):6984-5. PubMed ID: 17497780
[TBL] [Abstract][Full Text] [Related]
34. Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis.
Pereira HD; Franco GR; Cleasby A; Garratt RC
J Mol Biol; 2005 Oct; 353(3):584-99. PubMed ID: 16182308
[TBL] [Abstract][Full Text] [Related]
35. 8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.
Evans GB; Furneaux RH; Gainsford GJ; Hanson JC; Kicska GA; Sauve AA; Schramm VL; Tyler PC
J Med Chem; 2003 Jan; 46(1):155-60. PubMed ID: 12502369
[TBL] [Abstract][Full Text] [Related]
36. Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 A resolution.
Koellner G; Luić M; Shugar D; Saenger W; Bzowska A
J Mol Biol; 1997 Jan; 265(2):202-16. PubMed ID: 9020983
[TBL] [Abstract][Full Text] [Related]
37. Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone.
Koellner G; Stroh A; Raszewski G; Holý A; Bzowska A
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1699-702. PubMed ID: 14565499
[TBL] [Abstract][Full Text] [Related]
38. Second-sphere amino acids contribute to transition-state structure in bovine purine nucleoside phosphorylase.
Li L; Luo M; Ghanem M; Taylor EA; Schramm VL
Biochemistry; 2008 Feb; 47(8):2577-83. PubMed ID: 18281958
[TBL] [Abstract][Full Text] [Related]
39. Crystal structure of human PNP complexed with guanine.
de Azevedo WF; Canduri F; dos Santos DM; Pereira JH; Bertacine Dias MV; Silva RG; Mendes MA; Basso LA; Palma MS; Santos DS
Biochem Biophys Res Commun; 2003 Dec; 312(3):767-72. PubMed ID: 14680831
[TBL] [Abstract][Full Text] [Related]
40. Ternary complex crystal structures of glycogen phosphorylase with the transition state analogue nojirimycin tetrazole and phosphate in the T and R states.
Mitchell EP; Withers SG; Ermert P; Vasella AT; Garman EF; Oikonomakos NG; Johnson LN
Biochemistry; 1996 Jun; 35(23):7341-55. PubMed ID: 8652510
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]