These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 19944704)

  • 21. The role of strand 1 of the C beta-sheet in the structure and function of alpha(1)-antitrypsin.
    Bottomley SP; Lawrenson ID; Tew D; Dai W; Whisstock JC; Pike RN
    Protein Sci; 2001 Dec; 10(12):2518-24. PubMed ID: 11714919
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Accumulation of partly folded states in the equilibrium unfolding of ervatamin A: spectroscopic description of the native, intermediate, and unfolded states.
    Nallamsetty S; Dubey VK; Pande M; Ambasht PK; Jagannadham MV
    Biochimie; 2007 Nov; 89(11):1416-24. PubMed ID: 17658212
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Mechanisms of serpin dysfunction in disease.
    Kaiserman D; Whisstock JC; Bird PI
    Expert Rev Mol Med; 2006 Dec; 8(31):1-19. PubMed ID: 17156576
    [TBL] [Abstract][Full Text] [Related]  

  • 24. 6-mer peptide selectively anneals to a pathogenic serpin conformation and blocks polymerization. Implications for the prevention of Z alpha(1)-antitrypsin-related cirrhosis.
    Mahadeva R; Dafforn TR; Carrell RW; Lomas DA
    J Biol Chem; 2002 Mar; 277(9):6771-4. PubMed ID: 11773044
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Alpha1-antitrypsin polymerization and the serpinopathies: pathobiology and prospects for therapy.
    Lomas DA; Mahadeva R
    J Clin Invest; 2002 Dec; 110(11):1585-90. PubMed ID: 12464660
    [No Abstract]   [Full Text] [Related]  

  • 26. Prevention of polymerization of M and Z alpha1-Antitrypsin (alpha1-AT) with trimethylamine N-oxide. Implications for the treatment of alpha1-at deficiency.
    Devlin GL; Parfrey H; Tew DJ; Lomas DA; Bottomley SP
    Am J Respir Cell Mol Biol; 2001 Jun; 24(6):727-32. PubMed ID: 11415938
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Conformational changes in serpins: I. The native and cleaved conformations of alpha(1)-antitrypsin.
    Whisstock JC; Skinner R; Carrell RW; Lesk AM
    J Mol Biol; 2000 Feb; 296(2):685-99. PubMed ID: 10669617
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conformational change in elastase following complexation with alpha1-proteinase inhibitor: a CD investigation.
    Bousquet JA; Duranton J; Mély Y; Bieth JG
    Biochem J; 2003 Feb; 370(Pt 1):345-9. PubMed ID: 12413395
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Lung polymers in Z alpha1-antitrypsin deficiency-related emphysema.
    Elliott PR; Bilton D; Lomas DA
    Am J Respir Cell Mol Biol; 1998 May; 18(5):670-4. PubMed ID: 9569237
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Stabilisation of alpha-helices by site-directed mutagenesis reveals the importance of secondary structure in the transition state for acylphosphatase folding.
    Taddei N; Chiti F; Fiaschi T; Bucciantini M; Capanni C; Stefani M; Serrano L; Dobson CM; Ramponi G
    J Mol Biol; 2000 Jul; 300(3):633-47. PubMed ID: 10884358
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Wild-type alpha 1-antitrypsin is in the canonical inhibitory conformation.
    Elliott PR; Abrahams JP; Lomas DA
    J Mol Biol; 1998 Jan; 275(3):419-25. PubMed ID: 9466920
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Viscous drag as the source of active site perturbation during protease translocation: insights into how inhibitory processes are controlled by serpin metastability.
    Shin JS; Yu MH
    J Mol Biol; 2006 Jun; 359(2):378-89. PubMed ID: 16626735
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase.
    Whisstock J; Lesk AM; Carrell R
    Proteins; 1996 Nov; 26(3):288-303. PubMed ID: 8953650
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Thermodynamics and kinetics of folding of common-type acylphosphatase: comparison to the highly homologous muscle isoenzyme.
    Taddei N; Chiti F; Paoli P; Fiaschi T; Bucciantini M; Stefani M; Dobson CM; Ramponi G
    Biochemistry; 1999 Feb; 38(7):2135-42. PubMed ID: 10026297
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Serpin polymerization and its role in disease--the molecular basis of alpha1-antitrypsin deficiency.
    Knaupp AS; Bottomley SP
    IUBMB Life; 2009 Jan; 61(1):1-5. PubMed ID: 18785256
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Equilibrium and kinetic analyses of unfolding and refolding for the conserved proline mutants of tryptophan synthase alpha subunit.
    Ogasahara K; Yutani K
    Biochemistry; 1997 Jan; 36(4):932-40. PubMed ID: 9020793
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Probing the local conformational change of alpha1-antitrypsin.
    Baek JH; Im H; Kang UB; Seong KM; Lee C; Kim J; Yu MH
    Protein Sci; 2007 Sep; 16(9):1842-50. PubMed ID: 17660256
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Engineered tyrosine residues serve as the local probes to detect a kinetic intermediate in the folding of ribose-binding protein.
    Kim D; Kim C; Park C
    J Mol Biol; 1994 Jul; 240(4):385-95. PubMed ID: 8035461
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Global analysis of the acid-induced and urea-induced unfolding of staphylococcal nuclease and two of its variants.
    Ionescu RM; Eftink MR
    Biochemistry; 1997 Feb; 36(5):1129-40. PubMed ID: 9033404
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Acid Denaturation of alpha1-antitrypsin: characterization of a novel mechanism of serpin polymerization.
    Devlin GL; Chow MK; Howlett GJ; Bottomley SP
    J Mol Biol; 2002 Dec; 324(4):859-70. PubMed ID: 12460583
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.