117 related articles for article (PubMed ID: 19946930)
1. Cyclostreptin and microtubules: is a low-affinity binding site required?
Prussia AJ; Yang Y; Geballe MT; Snyder JP
Chembiochem; 2010 Jan; 11(1):101-9. PubMed ID: 19946930
[TBL] [Abstract][Full Text] [Related]
2. Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Buey RM; Calvo E; Barasoain I; Pineda O; Edler MC; Matesanz R; Cerezo G; Vanderwal CD; Day BW; Sorensen EJ; López JA; Andreu JM; Hamel E; Díaz JF
Nat Chem Biol; 2007 Feb; 3(2):117-25. PubMed ID: 17206139
[TBL] [Abstract][Full Text] [Related]
3. Crystal Structure of the Cyclostreptin-Tubulin Adduct: Implications for Tubulin Activation by Taxane-Site Ligands.
Balaguer FA; Mühlethaler T; Estévez-Gallego J; Calvo E; Giménez-Abián JF; Risinger AL; Sorensen EJ; Vanderwal CD; Altmann KH; Mooberry SL; Steinmetz MO; Oliva MÁ; Prota AE; Díaz JF
Int J Mol Sci; 2019 Mar; 20(6):. PubMed ID: 30897704
[TBL] [Abstract][Full Text] [Related]
4. Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α,β-heterodimers and microtubules.
Field JJ; Pera B; Calvo E; Canales A; Zurwerra D; Trigili C; Rodríguez-Salarichs J; Matesanz R; Kanakkanthara A; Wakefield SJ; Singh AJ; Jiménez-Barbero J; Northcote P; Miller JH; López JA; Hamel E; Barasoain I; Altmann KH; Díaz JF
Chem Biol; 2012 Jun; 19(6):686-98. PubMed ID: 22726683
[TBL] [Abstract][Full Text] [Related]
5. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site.
Edler MC; Buey RM; Gussio R; Marcus AI; Vanderwal CD; Sorensen EJ; Díaz JF; Giannakakou P; Hamel E
Biochemistry; 2005 Aug; 44(34):11525-38. PubMed ID: 16114889
[TBL] [Abstract][Full Text] [Related]
6. Molecular mechanism of action of microtubule-stabilizing anticancer agents.
Prota AE; Bargsten K; Zurwerra D; Field JJ; Díaz JF; Altmann KH; Steinmetz MO
Science; 2013 Feb; 339(6119):587-90. PubMed ID: 23287720
[TBL] [Abstract][Full Text] [Related]
7. Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site.
Calvo E; Barasoain I; Matesanz R; Pera B; Camafeita E; Pineda O; Hamel E; Vanderwal CD; Andreu JM; López JA; Díaz JF
Biochemistry; 2012 Jan; 51(1):329-41. PubMed ID: 22148836
[TBL] [Abstract][Full Text] [Related]
8. Interaction of a cyclostreptin analogue with the microtubule taxoid site: the covalent reaction rapidly follows binding.
Bai R; Vanderwal CD; Díaz JF; Hamel E
J Nat Prod; 2008 Mar; 71(3):370-4. PubMed ID: 18298077
[TBL] [Abstract][Full Text] [Related]
9. Structural Basis of Microtubule Stabilization by Discodermolide.
Prota AE; Bargsten K; Redondo-Horcajo M; Smith AB; Yang CH; McDaid HM; Paterson I; Horwitz SB; Fernando Díaz J; Steinmetz MO
Chembiochem; 2017 May; 18(10):905-909. PubMed ID: 28207984
[TBL] [Abstract][Full Text] [Related]
10. The microtubule-pore gatekeeper.
Snyder JP
Nat Chem Biol; 2007 Feb; 3(2):81-2. PubMed ID: 17235340
[No Abstract] [Full Text] [Related]
11. Relationship between the structures of taxane derivatives and their microtubule polymerization activity.
Hidaka M; Koga T; Kiyota H; Horiguchi T; Shi QW; Hirose K; Uchida T
Biosci Biotechnol Biochem; 2012; 76(2):349-52. PubMed ID: 22313785
[TBL] [Abstract][Full Text] [Related]
12. Methods for studying microtubule binding site interactions: zampanolide as a covalent binding agent.
Field JJ; Calvo E; Northcote PT; Miller JH; Altmann KH; Díaz JF
Methods Cell Biol; 2013; 115():303-25. PubMed ID: 23973080
[TBL] [Abstract][Full Text] [Related]
13. Molecular dynamics and tubulin polymerization kinetics study on 1,14-heterofused taxanes: evidence of stabilization of the tubulin head-to-tail dimer-dimer interaction.
Contini A; Cappelletti G; Cartelli D; Fontana G; Gelmi ML
Mol Biosyst; 2012 Oct; 8(12):3254-61. PubMed ID: 23073462
[TBL] [Abstract][Full Text] [Related]
14. Interaction of a fluorescent derivative of paclitaxel (Taxol) with microtubules and tubulin-colchicine.
Han Y; Chaudhary AG; Chordia MD; Sackett DL; Perez-Ramirez B; Kingston DG; Bane S
Biochemistry; 1996 Nov; 35(45):14173-83. PubMed ID: 8916903
[TBL] [Abstract][Full Text] [Related]
15. Taccalonolide binding to tubulin imparts microtubule stability and potent in vivo activity.
Risinger AL; Li J; Bennett MJ; Rohena CC; Peng J; Schriemer DC; Mooberry SL
Cancer Res; 2013 Nov; 73(22):6780-92. PubMed ID: 24048820
[TBL] [Abstract][Full Text] [Related]
16. Insights into the Distinct Mechanisms of Action of Taxane and Non-Taxane Microtubule Stabilizers from Cryo-EM Structures.
Kellogg EH; Hejab NMA; Howes S; Northcote P; Miller JH; Díaz JF; Downing KH; Nogales E
J Mol Biol; 2017 Mar; 429(5):633-646. PubMed ID: 28104363
[TBL] [Abstract][Full Text] [Related]
17. 3D QSAR models of interactions between beta-tubulin and microtubule stabilizing antimitotic agents (MSAA): a survey on taxanes and epothilones.
Manetti F; Maccari L; Corelli F; Botta M
Curr Top Med Chem; 2004; 4(2):203-17. PubMed ID: 14754454
[TBL] [Abstract][Full Text] [Related]
18. Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and computational approach.
Canales A; Rodríguez-Salarichs J; Trigili C; Nieto L; Coderch C; Andreu JM; Paterson I; Jiménez-Barbero J; Díaz JF
ACS Chem Biol; 2011 Aug; 6(8):789-99. PubMed ID: 21539341
[TBL] [Abstract][Full Text] [Related]
19. Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation.
Khrapunovich-Baine M; Menon V; Yang CP; Northcote PT; Miller JH; Angeletti RH; Fiser A; Horwitz SB; Xiao H
J Biol Chem; 2011 Apr; 286(13):11765-78. PubMed ID: 21245138
[TBL] [Abstract][Full Text] [Related]
20. High-resolution X-ray structure of three microtubule-stabilizing agents in complex with tubulin provide a rationale for drug design.
Xiao Q; Xue T; Shuai W; Wu C; Zhang Z; Zhang T; Zeng S; Sun B; Wang Y
Biochem Biophys Res Commun; 2021 Jan; 534():330-336. PubMed ID: 33272565
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
