BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 19951943)

  • 1. Role of arginine guanidinium moiety in nitric-oxide synthase mechanism of oxygen activation.
    Giroud C; Moreau M; Mattioli TA; Balland V; Boucher JL; Xu-Li Y; Stuehr DJ; Santolini J
    J Biol Chem; 2010 Mar; 285(10):7233-45. PubMed ID: 19951943
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N(ω)-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus.
    Davydov R; Labby KJ; Chobot SE; Lukoyanov DA; Crane BR; Silverman RB; Hoffman BM
    Biochemistry; 2014 Oct; 53(41):6511-9. PubMed ID: 25251261
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins.
    Crane BR; Arvai AS; Ghosh S; Getzoff ED; Stuehr DJ; Tainer JA
    Biochemistry; 2000 Apr; 39(16):4608-21. PubMed ID: 10769116
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Stabilization and characterization of a heme-oxy reaction intermediate in inducible nitric-oxide synthase.
    Tejero J; Biswas A; Wang ZQ; Page RC; Haque MM; Hemann C; Zweier JL; Misra S; Stuehr DJ
    J Biol Chem; 2008 Nov; 283(48):33498-507. PubMed ID: 18815130
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Nitrosyl-heme structures of Bacillus subtilis nitric oxide synthase have implications for understanding substrate oxidation.
    Pant K; Crane BR
    Biochemistry; 2006 Feb; 45(8):2537-44. PubMed ID: 16489746
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thermodynamic and kinetic analysis of the nitrosyl, carbonyl, and dioxy heme complexes of neuronal nitric-oxide synthase. The roles of substrate and tetrahydrobiopterin in oxygen activation.
    Ost TW; Daff S
    J Biol Chem; 2005 Jan; 280(2):965-73. PubMed ID: 15507439
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dissecting structural and electronic effects in inducible nitric oxide synthase.
    Hannibal L; Page RC; Haque MM; Bolisetty K; Yu Z; Misra S; Stuehr DJ
    Biochem J; 2015 Apr; 467(1):153-65. PubMed ID: 25608846
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling.
    Shamovsky I; Belfield G; Lewis R; Narjes F; Ripa L; Tyrchan C; Öberg L; Sjö P
    J Inorg Biochem; 2018 Apr; 181():28-40. PubMed ID: 29407906
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EPR and ENDOR characterization of intermediates in the cryoreduced oxy-nitric oxide synthase heme domain with bound L-arginine or N(G)-hydroxyarginine.
    Davydov R; Ledbetter-Rogers A; Martásek P; Larukhin M; Sono M; Dawson JH; Masters BS; Hoffman BM
    Biochemistry; 2002 Aug; 41(33):10375-81. PubMed ID: 12173923
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Is the bound substrate in nitric oxide synthase protonated or neutral and what is the active oxidant that performs substrate hydroxylation?
    de Visser SP; Tan LS
    J Am Chem Soc; 2008 Oct; 130(39):12961-74. PubMed ID: 18774806
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mechanism and regulation of ferrous heme-nitric oxide (NO) oxidation in NO synthases.
    Tejero J; Hunt AP; Santolini J; Lehnert N; Stuehr DJ
    J Biol Chem; 2019 May; 294(19):7904-7916. PubMed ID: 30926606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differential effects of alkyl- and arylguanidines on the stability and reactivity of inducible NOS heme-dioxygen complexes.
    Moreau M; Boucher JL; Mattioli TA; Stuehr DJ; Mansuy D; Santolini J
    Biochemistry; 2006 Mar; 45(12):3988-99. PubMed ID: 16548526
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comparison of wild type neuronal nitric oxide synthase and its Tyr588Phe mutant towards various L-arginine analogues.
    Giroud C; Moreau M; Sagami I; Shimizu T; Frapart Y; Mansuy D; Boucher JL
    J Inorg Biochem; 2010 Oct; 104(10):1043-50. PubMed ID: 20630600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Alternative nitric oxide-producing substrates for NO synthases.
    Mansuy D; Boucher JL
    Free Radic Biol Med; 2004 Oct; 37(8):1105-21. PubMed ID: 15451052
    [TBL] [Abstract][Full Text] [Related]  

  • 15. EPR and ENDOR characterization of the reactive intermediates in the generation of NO by cryoreduced oxy-nitric oxide synthase from Geobacillus stearothermophilus.
    Davydov R; Sudhamsu J; Lees NS; Crane BR; Hoffman BM
    J Am Chem Soc; 2009 Oct; 131(40):14493-507. PubMed ID: 19754116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The second step of the nitric oxide synthase reaction: evidence for ferric-peroxo as the active oxidant.
    Woodward JJ; Chang MM; Martin NI; Marletta MA
    J Am Chem Soc; 2009 Jan; 131(1):297-305. PubMed ID: 19128180
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Probing the Hydrogen Bonding of the Ferrous-NO Heme Center of nNOS by Pulsed Electron Paramagnetic Resonance.
    Astashkin AV; Chen L; Elmore BO; Kunwar D; Miao Y; Li H; Poulos TL; Roman LJ; Feng C
    J Phys Chem A; 2015 Jun; 119(25):6641-9. PubMed ID: 26035438
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Revisiting the Val/Ile Mutation in Mammalian and Bacterial Nitric Oxide Synthases: A Spectroscopic and Kinetic Study.
    Weisslocker-Schaetzel M; Lembrouk M; Santolini J; Dorlet P
    Biochemistry; 2017 Feb; 56(5):748-756. PubMed ID: 28074650
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Catalytic intermediates of inducible nitric-oxide synthase stabilized by the W188H mutation.
    Sabat J; Egawa T; Lu C; Stuehr DJ; Gerfen GJ; Rousseau DL; Yeh SR
    J Biol Chem; 2013 Mar; 288(9):6095-106. PubMed ID: 23269673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Heme distortion modulated by ligand-protein interactions in inducible nitric-oxide synthase.
    Li D; Stuehr DJ; Yeh SR; Rousseau DL
    J Biol Chem; 2004 Jun; 279(25):26489-99. PubMed ID: 15066989
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.