BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

307 related articles for article (PubMed ID: 19954977)

  • 1. 2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study.
    Basnet A; Thapa P; Karki R; Choi H; Choi JH; Yun M; Jeong BS; Jahng Y; Na Y; Cho WJ; Kwon Y; Lee CS; Lee ES
    Bioorg Med Chem Lett; 2010 Jan; 20(1):42-7. PubMed ID: 19954977
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 2-Thienyl-4-furyl-6-aryl pyridine derivatives: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Thapa P; Karki R; Thapa U; Jahng Y; Jung MJ; Nam JM; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 Jan; 18(1):377-86. PubMed ID: 19939682
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of hydroxylated 2,4-diphenyl-6-aryl pyridines.
    Karki R; Thapa P; Kang MJ; Jeong TC; Nam JM; Kim HL; Na Y; Cho WJ; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 May; 18(9):3066-77. PubMed ID: 20392646
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2,4,6-Trisubstituted pyridines: Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Basnet A; Thapa P; Karki R; Na Y; Jahng Y; Jeong BS; Jeong TC; Lee CS; Lee ES
    Bioorg Med Chem; 2007 Jul; 15(13):4351-9. PubMed ID: 17493824
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 2,4-diaryl chromenopyridines and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa U; Thapa P; Karki R; Yun M; Choi JH; Jahng Y; Lee E; Jeon KH; Na Y; Ha EM; Cho WJ; Kwon Y; Lee ES
    Eur J Med Chem; 2011 Aug; 46(8):3201-9. PubMed ID: 21601964
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dihydroxylated 2,4,6-triphenyl pyridines: synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study.
    Karki R; Thapa P; Yoo HY; Kadayat TM; Park PH; Na Y; Lee E; Jeon KH; Cho WJ; Choi H; Kwon Y; Lee ES
    Eur J Med Chem; 2012 Mar; 49():219-28. PubMed ID: 22318164
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, topoisomerase I inhibition and structure-activity relationship study of 2,4,6-trisubstituted pyridine derivatives.
    Zhao LX; Moon YS; Basnet A; Kim EK; Jahng Y; Park JG; Jeong TC; Cho WJ; Choi SU; Lee CO; Lee SY; Lee CS; Lee ES
    Bioorg Med Chem Lett; 2004 Mar; 14(5):1333-7. PubMed ID: 14980693
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
    Kadayat TM; Song C; Shin S; Magar TB; Bist G; Shrestha A; Thapa P; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Jul; 23(13):3499-512. PubMed ID: 26022080
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and topoisomerase II inhibitory and cytotoxic activity of oxiranylmethoxy- and thiiranylmethoxy-chalcone derivatives.
    Na Y; Nam JM
    Bioorg Med Chem Lett; 2011 Jan; 21(1):211-4. PubMed ID: 21115246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. New benzoxanthone derivatives as topoisomerase inhibitors and DNA cross-linkers.
    Cho HJ; Jung MJ; Woo S; Kim J; Lee ES; Kwon Y; Na Y
    Bioorg Med Chem; 2010 Feb; 18(3):1010-7. PubMed ID: 20093033
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and antitumor evaluation of 2,4,6-triaryl pyridines containing chlorophenyl and phenolic moiety.
    Thapa P; Karki R; Yun M; Kadayat TM; Lee E; Kwon HB; Na Y; Cho WJ; Kim ND; Jeong BS; Kwon Y; Lee ES
    Eur J Med Chem; 2012 Jun; 52():123-36. PubMed ID: 22503656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor agents. 3. Design, synthesis, and biological evaluation of new pyridoisoquinolindione and dihydrothienoquinolindione derivatives with potent cytotoxic activity.
    Bolognese A; Correale G; Manfra M; Lavecchia A; Mazzoni O; Novellino E; La Colla P; Sanna G; Loddo R
    J Med Chem; 2004 Feb; 47(4):849-58. PubMed ID: 14761187
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of 2-(thienyl-2-yl or -3-yl)-4-furyl-6-aryl pyridine derivatives and evaluation of their topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship.
    Thapa P; Karki R; Choi H; Choi JH; Yun M; Jeong BS; Jung MJ; Nam JM; Na Y; Cho WJ; Kwon Y; Lee ES
    Bioorg Med Chem; 2010 Mar; 18(6):2245-2254. PubMed ID: 20188578
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of 2,6-diaryl-substituted pyridines and their antitumor activities.
    Son JK; Zhao LX; Basnet A; Thapa P; Karki R; Na Y; Jahng Y; Jeong TC; Jeong BS; Lee CS; Lee ES
    Eur J Med Chem; 2008 Apr; 43(4):675-82. PubMed ID: 17673337
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
    Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological activity of 2,4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison.
    Karki R; Park C; Jun KY; Kadayat TM; Lee ES; Kwon Y
    Eur J Med Chem; 2015 Jan; 90():360-78. PubMed ID: 25437622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new series of 2-phenol-4-aryl-6-chlorophenyl pyridine derivatives as dual topoisomerase I/II inhibitors: Synthesis, biological evaluation and 3D-QSAR study.
    Karki R; Jun KY; Kadayat TM; Shin S; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Eur J Med Chem; 2016 May; 113():228-45. PubMed ID: 26945111
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of new xanthone analogues and their biological activity test--cytotoxicity, topoisomerase II inhibition, and DNA cross-linking study.
    Woo S; Jung J; Lee C; Kwon Y; Na Y
    Bioorg Med Chem Lett; 2007 Mar; 17(5):1163-6. PubMed ID: 17194586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents.
    Thapa P; Jun KY; Kadayat TM; Park C; Zheng Z; Thapa Magar TB; Bist G; Shrestha A; Na Y; Kwon Y; Lee ES
    Bioorg Med Chem; 2015 Oct; 23(19):6454-66. PubMed ID: 26361737
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, antitumor activity, and structure-activity relationship study of trihydroxylated 2,4,6-triphenyl pyridines as potent and selective topoisomerase II inhibitors.
    Karki R; Park C; Jun KY; Jee JG; Lee JH; Thapa P; Kadayat TM; Kwon Y; Lee ES
    Eur J Med Chem; 2014 Sep; 84():555-65. PubMed ID: 25062006
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.