BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

111 related articles for article (PubMed ID: 1995897)

  • 1. Allosteric modifiers of hemoglobin. 1. Design, synthesis, testing, and structure-allosteric activity relationship of novel hemoglobin oxygen affinity decreasing agents.
    Randad RS; Mahran MA; Mehanna AS; Abraham DJ
    J Med Chem; 1991 Feb; 34(2):752-7. PubMed ID: 1995897
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Allosteric modifiers of hemoglobin: 2-[4-[[(3,5-disubstituted anilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid derivatives that lower the oxygen affinity of hemoglobin in red cell suspensions, in whole blood, and in vivo in rats.
    Abraham DJ; Wireko FC; Randad RS; Poyart C; Kister J; Bohn B; Liard JF; Kunert MP
    Biochemistry; 1992 Sep; 31(38):9141-9. PubMed ID: 1390701
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and investigation of effects of 2-[4- [[(arylamino)carbonyl]amino]phenoxy]-2-methylpropionic acids on the affinity of hemoglobin for oxygen: structure-activity relationships.
    Lalezari I; Lalezari P
    J Med Chem; 1989 Oct; 32(10):2352-7. PubMed ID: 2795607
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effect of an allosteric modifier of hemoglobin, RSR-4, on oxygen affinity and oxygen saturation of hemoglobin in rabbits.
    Uchida K; Reilly MP; Abraham DJ; Asakura T
    Jpn J Physiol; 1998 Dec; 48(6):439-44. PubMed ID: 10021497
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector.
    Safo MK; Moure CM; Burnett JC; Joshi GS; Abraham DJ
    Protein Sci; 2001 May; 10(5):951-7. PubMed ID: 11316875
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and structure-activity relationships of chiral allosteric modifiers of hemoglobin.
    Phelps Grella M; Danso-Danquah R; Safo MK; Joshi GS; Kister J; Marden M; Hoffman SJ; Abraham DJ
    J Med Chem; 2000 Dec; 43(25):4726-37. PubMed ID: 11123981
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RSR13, a synthetic allosteric modifier of hemoglobin, improves myocardial recovery following hypothermic cardiopulmonary bypass.
    Kilgore KS; Shwartz CF; Gallagher MA; Steffen RP; Mosca RS; Bolling SF
    Circulation; 1999 Nov; 100(19 Suppl):II351-6. PubMed ID: 10567328
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Aryloxyalkanoic Acids as Non-Covalent Modifiers of the Allosteric Properties of Hemoglobin.
    Omar AM; Mahran MA; Ghatge MS; Bamane FH; Ahmed MH; El-Araby ME; Abdulmalik O; Safo MK
    Molecules; 2016 Aug; 21(8):. PubMed ID: 27529207
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Allosteric effectors of hemoglobin as modulators of chemotherapy and radiation therapy in vitro and in vivo.
    Teicher BA; Wong JS; Takeuchi H; Gravelin LM; Ara G; Buxton D
    Cancer Chemother Pharmacol; 1998; 42(1):24-30. PubMed ID: 9619754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effects of a synthetic allosteric modifier of hemoglobin oxygen affinity on outcome from global cerebral ischemia in the rat.
    Grocott HP; Bart RD; Sheng H; Miura Y; Steffen R; Pearlstein RD; Warner DS
    Stroke; 1998 Aug; 29(8):1650-5. PubMed ID: 9707208
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preservation of canine myocardial high-energy phosphates during low-flow ischemia with modification of hemoglobin-oxygen affinity.
    Weiss RG; Mejia MA; Kass DA; DiPaula AF; Becker LC; Gerstenblith G; Chacko VP
    J Clin Invest; 1999 Mar; 103(5):739-46. PubMed ID: 10074492
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Allosteric modification of oxygen delivery by hemoglobin.
    Wahr JA; Gerber M; Venitz J; Baliga N
    Anesth Analg; 2001 Mar; 92(3):615-20. PubMed ID: 11226087
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of RSR13, a synthetic allosteric modifier of hemoglobin, alone and in combination with dizocilpine, on outcome from transient focal cerebral ischemia in the rat.
    Sarraf-Yazdi S; Sheng H; Grocott HP; Bart RD; Pearlstein RD; Steffen RP; Warner DS
    Brain Res; 1999 May; 826(2):172-80. PubMed ID: 10224294
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesized allosteric effectors of the hemoglobin molecule: a possible mechanism for improved erythrocyte oxygen release capability in hemoglobinopathy H disease.
    Papassotiriou I; Kister J; Griffon N; Abraham DJ; Kanavakis E; Traeger-Synodinos J; Stamoulakatou A; Marden MC; Poyart C
    Exp Hematol; 1998 Sep; 26(10):922-6. PubMed ID: 9728926
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyridyl derivatives of benzaldehyde as potential antisickling agents.
    Nnamani IN; Joshi GS; Danso-Danquah R; Abdulmalik O; Asakura T; Abraham DJ; Safo MK
    Chem Biodivers; 2008 Sep; 5(9):1762-9. PubMed ID: 18816529
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids.
    Abraham DJ; Kennedy PE; Mehanna AS; Patwa DC; Williams FL
    J Med Chem; 1984 Aug; 27(8):967-78. PubMed ID: 6747995
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intrinsic activity at the molecular level: E. J. AriĆ«ns' concept visualized.
    Abraham DJ; Kister J; Joshi GS; Marden MC; Poyart C
    J Mol Biol; 1995 May; 248(4):845-55. PubMed ID: 7752245
    [TBL] [Abstract][Full Text] [Related]  

  • 18. X-ray crystallographic analyses of symmetrical allosteric effectors of hemoglobin: compounds designed to link primary and secondary binding sites.
    Safo MK; Boyiri T; Burnett JC; Danso-Danquah R; Moure CM; Joshi GS; Abraham DJ
    Acta Crystallogr D Biol Crystallogr; 2002 Apr; 58(Pt 4):634-44. PubMed ID: 11914488
    [TBL] [Abstract][Full Text] [Related]  

  • 19. How allosteric effectors can bind to the same protein residue and produce opposite shifts in the allosteric equilibrium.
    Abraham DJ; Safo MK; Boyiri T; Danso-Danquah RE; Kister J; Poyart C
    Biochemistry; 1995 Nov; 34(46):15006-20. PubMed ID: 7578114
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative structure-activity relationship of phenoxy and benzyloxy acid derivatives as antisickling agents.
    Mahran MA
    Boll Chim Farm; 2000; 139(2):73-80. PubMed ID: 10920532
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.