BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

433 related articles for article (PubMed ID: 19959470)

  • 1. Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein.
    Saxena G; Chen J; Shalev A
    J Biol Chem; 2010 Feb; 285(6):3997-4005. PubMed ID: 19959470
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Blocking CHOP-dependent TXNIP shuttling to mitochondria attenuates albuminuria and mitigates kidney injury in nephrotic syndrome.
    Park SJ; Kim Y; Li C; Suh J; Sivapackiam J; Goncalves TM; Jarad G; Zhao G; Urano F; Sharma V; Chen YM
    Proc Natl Acad Sci U S A; 2022 Aug; 119(35):e2116505119. PubMed ID: 35994650
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Age-related changes in mitochondrial antioxidant enzyme Trx2 and TXNIP-Trx2-ASK1 signal pathways in the auditory cortex of a mimetic aging rat model: changes to Trx2 in the auditory cortex.
    Sun HY; Hu YJ; Zhao XY; Zhong Y; Zeng LL; Chen XB; Yuan J; Wu J; Sun Y; Kong W; Kong WJ
    FEBS J; 2015 Jul; 282(14):2758-74. PubMed ID: 25996168
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.
    Zhang R; Al-Lamki R; Bai L; Streb JW; Miano JM; Bradley J; Min W
    Circ Res; 2004 Jun; 94(11):1483-91. PubMed ID: 15117824
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High beta-cell mass prevents streptozotocin-induced diabetes in thioredoxin-interacting protein-deficient mice.
    Masson E; Koren S; Razik F; Goldberg H; Kwan EP; Sheu L; Gaisano HY; Fantus IG
    Am J Physiol Endocrinol Metab; 2009 Jun; 296(6):E1251-61. PubMed ID: 19223654
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.
    Chen J; Fontes G; Saxena G; Poitout V; Shalev A
    Diabetes; 2010 Feb; 59(2):440-7. PubMed ID: 19875615
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nitrosative/oxidative stress conditions regulate thioredoxin-interacting protein (TXNIP) expression and thioredoxin-1 (TRX-1) nuclear localization.
    Ogata FT; Batista WL; Sartori A; Gesteira TF; Masutani H; Arai RJ; Yodoi J; Stern A; Monteiro HP
    PLoS One; 2013; 8(12):e84588. PubMed ID: 24376827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.
    Chen J; Saxena G; Mungrue IN; Lusis AJ; Shalev A
    Diabetes; 2008 Apr; 57(4):938-44. PubMed ID: 18171713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MiR-17 Downregulation by High Glucose Stabilizes Thioredoxin-Interacting Protein and Removes Thioredoxin Inhibition on ASK1 Leading to Apoptosis.
    Dong D; Fu N; Yang P
    Toxicol Sci; 2016 Mar; 150(1):84-96. PubMed ID: 26660634
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thioredoxin-interacting protein mediates TRX1 translocation to the plasma membrane in response to tumor necrosis factor-α: a key mechanism for vascular endothelial growth factor receptor-2 transactivation by reactive oxygen species.
    World C; Spindel ON; Berk BC
    Arterioscler Thromb Vasc Biol; 2011 Aug; 31(8):1890-7. PubMed ID: 21636804
    [TBL] [Abstract][Full Text] [Related]  

  • 11. W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.
    Li T; Lin GY; Zhong L; Zhou Y; Wang J; Zhu Y; Feng Y; Cai XQ; Liu Q; Nosjean O; Boutin JA; Renard P; Yang DH; Wang MW
    Acta Pharmacol Sin; 2017 Jul; 38(7):1024-1037. PubMed ID: 28502980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.
    Chen J; Hui ST; Couto FM; Mungrue IN; Davis DB; Attie AD; Lusis AJ; Davis RA; Shalev A
    FASEB J; 2008 Oct; 22(10):3581-94. PubMed ID: 18552236
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Thioredoxin-Interacting Protein Deficiency Protects against Diabetic Nephropathy.
    Shah A; Xia L; Masson EA; Gui C; Momen A; Shikatani EA; Husain M; Quaggin S; John R; Fantus IG
    J Am Soc Nephrol; 2015 Dec; 26(12):2963-77. PubMed ID: 25855771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms of Trx2/ASK1-Mediated Mitochondrial Injury in Pemphigus Vulgaris.
    Wei B; Li F
    Biomed Res Int; 2021; 2021():2471518. PubMed ID: 33763469
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytokines Regulate β-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
    Hong K; Xu G; Grayson TB; Shalev A
    J Biol Chem; 2016 Apr; 291(16):8428-39. PubMed ID: 26858253
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Thioredoxin-interacting protein regulates insulin transcription through microRNA-204.
    Xu G; Chen J; Jing G; Shalev A
    Nat Med; 2013 Sep; 19(9):1141-6. PubMed ID: 23975026
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ceramide induces p38 MAPK and JNK activation through a mechanism involving a thioredoxin-interacting protein-mediated pathway.
    Chen CL; Lin CF; Chang WT; Huang WC; Teng CF; Lin YS
    Blood; 2008 Apr; 111(8):4365-74. PubMed ID: 18270325
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TXNIP contributes to bone loss via promoting the mitochondrial oxidative phosphorylation during glucocorticoid-induced osteoporosis.
    Mo Y; Lai W; Zhong Y; Hu Z; You M; Du M; Wang P; Wu X; Chen C; He H; Gao Z; Xu Y; Wang D; Cui L; Yang Y
    Life Sci; 2021 Feb; 266():118938. PubMed ID: 33347878
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TXNIP, a novel key factor to cause Schwann cell dysfunction in diabetic peripheral neuropathy, under the regulation of PI3K/Akt pathway inhibition-induced DNMT1 and DNMT3a overexpression.
    Zhang X; Zhao S; Yuan Q; Zhu L; Li F; Wang H; Kong D; Hao J
    Cell Death Dis; 2021 Jun; 12(7):642. PubMed ID: 34162834
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis.
    Dai S; He Y; Zhang H; Yu L; Wan T; Xu Z; Jones D; Chen H; Min W
    Arterioscler Thromb Vasc Biol; 2009 Apr; 29(4):495-502. PubMed ID: 19150880
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.