352 related articles for article (PubMed ID: 19959756)
1. Glucose induces pancreatic islet cell apoptosis that requires the BH3-only proteins Bim and Puma and multi-BH domain protein Bax.
McKenzie MD; Jamieson E; Jansen ES; Scott CL; Huang DC; Bouillet P; Allison J; Kay TW; Strasser A; Thomas HE
Diabetes; 2010 Mar; 59(3):644-52. PubMed ID: 19959756
[TBL] [Abstract][Full Text] [Related]
2. BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
Ren D; Tu HC; Kim H; Wang GX; Bean GR; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
Science; 2010 Dec; 330(6009):1390-3. PubMed ID: 21127253
[TBL] [Abstract][Full Text] [Related]
3. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
[TBL] [Abstract][Full Text] [Related]
4. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T
J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309
[TBL] [Abstract][Full Text] [Related]
5. Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim.
Jabbour AM; Heraud JE; Daunt CP; Kaufmann T; Sandow J; O'Reilly LA; Callus BA; Lopez A; Strasser A; Vaux DL; Ekert PG
Cell Death Differ; 2009 Apr; 16(4):555-63. PubMed ID: 19079139
[TBL] [Abstract][Full Text] [Related]
6. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
Willis SN; Fletcher JI; Kaufmann T; van Delft MF; Chen L; Czabotar PE; Ierino H; Lee EF; Fairlie WD; Bouillet P; Strasser A; Kluck RM; Adams JM; Huang DC
Science; 2007 Feb; 315(5813):856-9. PubMed ID: 17289999
[TBL] [Abstract][Full Text] [Related]
7. Stepwise activation of BAX and BAK by tBID, BIM, and PUMA initiates mitochondrial apoptosis.
Kim H; Tu HC; Ren D; Takeuchi O; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
Mol Cell; 2009 Nov; 36(3):487-99. PubMed ID: 19917256
[TBL] [Abstract][Full Text] [Related]
8. Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies.
Kim H; Rafiuddin-Shah M; Tu HC; Jeffers JR; Zambetti GP; Hsieh JJ; Cheng EH
Nat Cell Biol; 2006 Dec; 8(12):1348-58. PubMed ID: 17115033
[TBL] [Abstract][Full Text] [Related]
9. Proapoptotic BH3-only protein Bid is essential for death receptor-induced apoptosis of pancreatic beta-cells.
McKenzie MD; Carrington EM; Kaufmann T; Strasser A; Huang DC; Kay TW; Allison J; Thomas HE
Diabetes; 2008 May; 57(5):1284-92. PubMed ID: 18252892
[TBL] [Abstract][Full Text] [Related]
10. The proapoptotic BH3-only, Bcl-2 family member, Puma is critical for acute ethanol-induced neuronal apoptosis.
Ghosh AP; Walls KC; Klocke BJ; Toms R; Strasser A; Roth KA
J Neuropathol Exp Neurol; 2009 Jul; 68(7):747-56. PubMed ID: 19535997
[TBL] [Abstract][Full Text] [Related]
11. BH3 mimetic ABT-737 potentiates TRAIL-mediated apoptotic signaling by unsequestering Bim and Bak in human pancreatic cancer cells.
Huang S; Sinicrope FA
Cancer Res; 2008 Apr; 68(8):2944-51. PubMed ID: 18413764
[TBL] [Abstract][Full Text] [Related]
12. Genetically defining the mechanism of Puma- and Bim-induced apoptosis.
Garrison SP; Phillips DC; Jeffers JR; Chipuk JE; Parsons MJ; Rehg JE; Opferman JT; Green DR; Zambetti GP
Cell Death Differ; 2012 Apr; 19(4):642-9. PubMed ID: 22015606
[TBL] [Abstract][Full Text] [Related]
13. Cell biology. Opening the cellular poison cabinet.
Martin SJ
Science; 2010 Dec; 330(6009):1330-1. PubMed ID: 21127237
[No Abstract] [Full Text] [Related]
14. Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.
Zhang L; Lopez H; George NM; Liu X; Pang X; Luo X
Cell Death Differ; 2011 May; 18(5):864-73. PubMed ID: 21113147
[TBL] [Abstract][Full Text] [Related]
15. BAX and BAK caught in the act.
Yao Y; Marassi FM
Mol Cell; 2009 Nov; 36(3):353-4. PubMed ID: 19917244
[TBL] [Abstract][Full Text] [Related]
16. Modulation of Bcl-2-related protein expression in pancreatic beta cells by pro-inflammatory cytokines and its dependence on the antioxidative defense status.
Mehmeti I; Lenzen S; Lortz S
Mol Cell Endocrinol; 2011 Jan; 332(1-2):88-96. PubMed ID: 20933054
[TBL] [Abstract][Full Text] [Related]
17. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
[TBL] [Abstract][Full Text] [Related]
18. Bim(L) displacing Bcl-x(L) promotes Bax translocation during TNFalpha-induced apoptosis.
Zhang L; Xing D; Chen M
Apoptosis; 2008 Jul; 13(7):950-8. PubMed ID: 18500555
[TBL] [Abstract][Full Text] [Related]
19. BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.
Erlacher M; Michalak EM; Kelly PN; Labi V; Niederegger H; Coultas L; Adams JM; Strasser A; Villunger A
Blood; 2005 Dec; 106(13):4131-8. PubMed ID: 16118324
[TBL] [Abstract][Full Text] [Related]
20. Mitochondrial apoptosis induced by BH3-only molecules in the exclusive presence of endoplasmic reticular Bak.
Klee M; Pallauf K; Alcalá S; Fleischer A; Pimentel-Muiños FX
EMBO J; 2009 Jun; 28(12):1757-68. PubMed ID: 19339988
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
