BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

71 related articles for article (PubMed ID: 19959816)

  • 1. Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays.
    Yu XC; Miranda M; Liu Z; Patel S; Nguyen N; Carson K; Liu Q; Swaffield JC
    J Biomol Screen; 2010 Jan; 15(1):72-9. PubMed ID: 19959816
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Casein kinase 1delta activates human recombinant deoxycytidine kinase by Ser-74 phosphorylation, but is not involved in the in vivo regulation of its activity.
    Smal C; Vertommen D; Amsailale R; Arts A; Degand H; Morsomme P; Rider MH; Neste EV; Bontemps F
    Arch Biochem Biophys; 2010 Oct; 502(1):44-52. PubMed ID: 20637175
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Integration of virtual screening with high-throughput screening for the identification of novel Rho-kinase I inhibitors.
    Gong LL; Fang LH; Peng JH; Liu AL; Du GH
    J Biotechnol; 2010 Feb; 145(3):295-303. PubMed ID: 19963024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells.
    Smal C; Cardoen S; Bertrand L; Delacauw A; Ferrant A; Van den Berghe G; Van Den Neste E; Bontemps F
    Biochem Pharmacol; 2004 Jul; 68(1):95-103. PubMed ID: 15183121
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retroviral transfer of deoxycytidine kinase into tumor cell lines enhances nucleoside toxicity.
    Hapke DM; Stegmann AP; Mitchell BS
    Cancer Res; 1996 May; 56(10):2343-7. PubMed ID: 8625309
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy.
    Sabini E; Ort S; Monnerjahn C; Konrad M; Lavie A
    Nat Struct Biol; 2003 Jul; 10(7):513-9. PubMed ID: 12808445
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy.
    Johnsamuel J; Eriksson S; Oliveira M; Tjarks W
    Bioorg Med Chem; 2005 Jul; 13(13):4160-7. PubMed ID: 15876539
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytosine arabinoside affects multiple cellular factors and induces drug resistance in human lymphoid cells.
    Sarkar M; Han T; Damaraju V; Carpenter P; Cass CE; Agarwal RP
    Biochem Pharmacol; 2005 Aug; 70(3):426-32. PubMed ID: 15950950
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Activation of deoxycytidine kinase by deoxyadenosine: implications in deoxyadenosine-mediated cytotoxicity.
    Keszler G; Virga S; Spasokoukotskaja T; Bauer PI; Sasvari-Szekely M; Staub M
    Arch Biochem Biophys; 2005 Apr; 436(1):69-77. PubMed ID: 15752710
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase.
    Tarver JE; Jessop TC; Carlsen M; Augeri DJ; Fu Q; Healy JP; Heim-Riether A; Xu A; Taylor JA; Shen M; Keyes PE; David Kimball S; Yu XC; Miranda M; Liu Q; Swaffield JC; Nouraldeen A; Wilson AG; Finch R; Jhaver K; Foushee AM; Anderson S; Oravecz T; Carson KG
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6780-3. PubMed ID: 19836229
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The pattern of deoxycytidine- and deoxyguanosine kinase activity in relation to messenger RNA expression in blood cells from untreated patients with B-cell chronic lymphocytic leukemia.
    Lotfi K; Karlsson K; Fyrberg A; Juliusson G; Jonsson V; Peterson C; Eriksson S; Albertioni F
    Biochem Pharmacol; 2006 Mar; 71(6):882-90. PubMed ID: 16436271
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.
    Jessop TC; Tarver JE; Carlsen M; Xu A; Healy JP; Heim-Riether A; Fu Q; Taylor JA; Augeri DJ; Shen M; Stouch TR; Swanson RV; Tari LW; Hunter M; Hoffman I; Keyes PE; Yu XC; Miranda M; Liu Q; Swaffield JC; David Kimball S; Nouraldeen A; Wilson AG; Foushee AM; Jhaver K; Finch R; Anderson S; Oravecz T; Carson KG
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6784-7. PubMed ID: 19836232
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Special function of deoxycytidine kinase (dCK) in the activation of chemotherapeutic nucleoside analogs and in the inhibition of cell proliferation].
    Staub M
    Magy Onkol; 2004; 48(3):229-34. PubMed ID: 15520873
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase.
    Rodriguez CO; Mitchell BS; Ayres M; Eriksson S; Gandhi V
    Cancer Res; 2002 Jun; 62(11):3100-5. PubMed ID: 12036920
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Resistance to 1-beta-D-arabinofuranosylcytosine in human T-lymphoblasts mediated by mutations within the deoxycytidine kinase gene.
    Owens JK; Shewach DS; Ullman B; Mitchell BS
    Cancer Res; 1992 May; 52(9):2389-93. PubMed ID: 1568208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of human deoxycytidine kinase activity as a response to cellular stress induced by NaF.
    Csapó Z; Sasvári-Székely M; Spasokoukotskaja T; Staub M
    Acta Biochim Pol; 2001; 48(1):251-6. PubMed ID: 11440177
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the molecules.
    Nomme J; Murphy JM; Su Y; Sansone ND; Armijo AL; Olson ST; Radu C; Lavie A
    Acta Crystallogr D Biol Crystallogr; 2014 Jan; 70(Pt 1):68-78. PubMed ID: 24419380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular and biochemical mechanisms of fludarabine and cladribine resistance in a human promyelocytic cell line.
    Månsson E; Spasokoukotskaja T; Sällström J; Eriksson S; Albertioni F
    Cancer Res; 1999 Dec; 59(23):5956-63. PubMed ID: 10606241
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New evidences for a regulation of deoxycytidine kinase activity by reversible phosphorylation.
    Smal C; Bertrand L; Van den Neste E; Cardoen S; Veiga-da-Cunha M; Marie S; Race V; Ferrant A; Van den Berghe G; Bontemps F
    Nucleosides Nucleotides Nucleic Acids; 2004 Oct; 23(8-9):1363-5. PubMed ID: 15571259
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A homogeneous time-resolved fluorescence-based high-throughput screening system for discovery of inhibitors of IKKbeta-NEMO interaction.
    Gotoh Y; Nagata H; Kase H; Shimonishi M; Ido M
    Anal Biochem; 2010 Oct; 405(1):19-27. PubMed ID: 20522330
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.