245 related articles for article (PubMed ID: 19963024)
1. Integration of virtual screening with high-throughput screening for the identification of novel Rho-kinase I inhibitors.
Gong LL; Fang LH; Peng JH; Liu AL; Du GH
J Biotechnol; 2010 Feb; 145(3):295-303. PubMed ID: 19963024
[TBL] [Abstract][Full Text] [Related]
2. Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays.
Yu XC; Miranda M; Liu Z; Patel S; Nguyen N; Carson K; Liu Q; Swaffield JC
J Biomol Screen; 2010 Jan; 15(1):72-9. PubMed ID: 19959816
[TBL] [Abstract][Full Text] [Related]
3. The discovery of novel vascular endothelial growth factor receptor tyrosine kinases inhibitors: pharmacophore modeling, virtual screening and docking studies.
Yu H; Wang Z; Zhang L; Zhang J; Huang Q
Chem Biol Drug Des; 2007 Mar; 69(3):204-11. PubMed ID: 17441906
[TBL] [Abstract][Full Text] [Related]
4. Pharmacophore modeling and virtual screening for the discovery of new transforming growth factor-beta type I receptor (ALK5) inhibitors.
Ren JX; Li LL; Zou J; Yang L; Yang JL; Yang SY
Eur J Med Chem; 2009 Nov; 44(11):4259-65. PubMed ID: 19640613
[TBL] [Abstract][Full Text] [Related]
5. Virtual screening for Raf-1 kinase inhibitors based on pharmacophore model of substituted ureas.
Li HF; Lu T; Zhu T; Jiang YJ; Rao SS; Hu LY; Xin BT; Chen YD
Eur J Med Chem; 2009 Mar; 44(3):1240-9. PubMed ID: 18947905
[TBL] [Abstract][Full Text] [Related]
6. Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle: 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one.
Letellier MA; Guillard J; Caignard DH; Ferry G; Boutin JA; Viaud-Massuard MC
Eur J Med Chem; 2008 Aug; 43(8):1730-6. PubMed ID: 18164518
[TBL] [Abstract][Full Text] [Related]
7. Discovery of novel Pim-1 kinase inhibitors by a hierarchical multistage virtual screening approach based on SVM model, pharmacophore, and molecular docking.
Ren JX; Li LL; Zheng RL; Xie HZ; Cao ZX; Feng S; Pan YL; Chen X; Wei YQ; Yang SY
J Chem Inf Model; 2011 Jun; 51(6):1364-75. PubMed ID: 21618971
[TBL] [Abstract][Full Text] [Related]
8. Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors.
Schröter T; Griffin E; Weiser A; Feng Y; LoGrasso P
Biochem Biophys Res Commun; 2008 Sep; 374(2):356-60. PubMed ID: 18638453
[TBL] [Abstract][Full Text] [Related]
9. Hit to lead account of the discovery of bisbenzamide and related ureidobenzamide inhibitors of Rho kinase.
Morwick T; Büttner FH; Cywin CL; Dahmann G; Hickey E; Jakes S; Kaplita P; Kashem MA; Kerr S; Kugler S; Mao W; Marshall D; Paw Z; Shih CK; Wu F; Young E
J Med Chem; 2010 Jan; 53(2):759-77. PubMed ID: 20000469
[TBL] [Abstract][Full Text] [Related]
10. Improved lead-finding for kinase targets using high-throughput docking.
McInnes C
Curr Opin Drug Discov Devel; 2006 May; 9(3):339-47. PubMed ID: 16729730
[TBL] [Abstract][Full Text] [Related]
11. High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.
Andrews PD; Becroft M; Aspegren A; Gilmour J; James MJ; McRae S; Kime R; Allcock RW; Abraham A; Jiang Z; Strehl R; Mountford JC; Milligan G; Houslay MD; Adams DR; Frearson JA
Biochem J; 2010 Nov; 432(1):21-33. PubMed ID: 20854259
[TBL] [Abstract][Full Text] [Related]
12. Identification of death-associated protein kinases inhibitors using structure-based virtual screening.
Okamoto M; Takayama K; Shimizu T; Ishida K; Takahashi O; Furuya T
J Med Chem; 2009 Nov; 52(22):7323-7. PubMed ID: 19877644
[TBL] [Abstract][Full Text] [Related]
13. The development of benzimidazoles as selective rho kinase inhibitors.
Sessions EH; Smolinski M; Wang B; Frackowiak B; Chowdhury S; Yin Y; Chen YT; Ruiz C; Lin L; Pocas J; Schröter T; Cameron MD; LoGrasso P; Feng Y; Bannister TD
Bioorg Med Chem Lett; 2010 Mar; 20(6):1939-43. PubMed ID: 20167489
[TBL] [Abstract][Full Text] [Related]
14. Computational approach to the identification of novel Aurora-A inhibitors.
Morshed MN; Cho YS; Seo SH; Han KC; Yang EG; Pae AN
Bioorg Med Chem; 2011 Jan; 19(2):907-16. PubMed ID: 21194953
[TBL] [Abstract][Full Text] [Related]
15. IKKbeta inhibitors identification part I: homology model assisted structure based virtual screening.
Nagarajan S; Doddareddy Mr; Choo H; Cho YS; Oh KS; Lee BH; Pae AN
Bioorg Med Chem; 2009 Apr; 17(7):2759-66. PubMed ID: 19285872
[TBL] [Abstract][Full Text] [Related]
16. Design of novel rho kinase inhibitors using energy based pharmacophore modeling, shape-based screening, in silico virtual screening, and biological evaluation.
Mishra RK; Alokam R; Singhal SM; Srivathsav G; Sriram D; Kaushik-Basu N; Manvar D; Yogeeswari P
J Chem Inf Model; 2014 Oct; 54(10):2876-86. PubMed ID: 25254429
[TBL] [Abstract][Full Text] [Related]
17. High-throughput screening for kinase inhibitors.
von Ahsen O; Bömer U
Chembiochem; 2005 Mar; 6(3):481-90. PubMed ID: 15742384
[TBL] [Abstract][Full Text] [Related]
18. High-throughput virtual screening of proteins using GRID molecular interaction fields.
Sciabola S; Stanton RV; Mills JE; Flocco MM; Baroni M; Cruciani G; Perruccio F; Mason JS
J Chem Inf Model; 2010 Jan; 50(1):155-69. PubMed ID: 19919042
[TBL] [Abstract][Full Text] [Related]
19. Triazine and pyrimidine based ROCK inhibitors with efficacy in spontaneous hypertensive rat model.
Ho KK; Beasley JR; Belanger L; Black D; Chan JH; Dunn D; Hu B; Klon A; Kultgen SG; Ohlmeyer M; Parlato SM; Ray PC; Pham Q; Rong Y; Roughton AL; Walker TL; Wright J; Xu K; Xu Y; Zhang L; Webb M
Bioorg Med Chem Lett; 2009 Nov; 19(21):6027-31. PubMed ID: 19800787
[TBL] [Abstract][Full Text] [Related]
20. Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor.
Yarrow JC; Totsukawa G; Charras GT; Mitchison TJ
Chem Biol; 2005 Mar; 12(3):385-95. PubMed ID: 15797222
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]