These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 19965579)

  • 1. Prelamin A prenylation and the treatment of progeria.
    Worman HJ
    J Lipid Res; 2010 Feb; 51(2):223-5. PubMed ID: 19965579
    [No Abstract]   [Full Text] [Related]  

  • 2. An encouraging progress report on the treatment of progeria and its implications for atherogenesis.
    Oshima J; Hisama FM; Martin GM
    Circulation; 2014 Jul; 130(1):4-6. PubMed ID: 24795391
    [No Abstract]   [Full Text] [Related]  

  • 3. N6-isopentenyladenosine improves nuclear shape in fibroblasts from humans with progeroid syndromes by inhibiting the farnesylation of prelamin A.
    Bifulco M; D'Alessandro A; Paladino S; Malfitano AM; Notarnicola M; Caruso MG; Laezza C
    FEBS J; 2013 Dec; 280(23):6223-32. PubMed ID: 24112551
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Investigating the purpose of prelamin A processing.
    Davies BS; Coffinier C; Yang SH; Barnes RH; Jung HJ; Young SG; Fong LG
    Nucleus; 2011; 2(1):4-9. PubMed ID: 21647293
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Prelamin A farnesylation and progeroid syndromes.
    Young SG; Meta M; Yang SH; Fong LG
    J Biol Chem; 2006 Dec; 281(52):39741-5. PubMed ID: 17090536
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An accumulation of non-farnesylated prelamin A causes cardiomyopathy but not progeria.
    Davies BS; Barnes RH; Tu Y; Ren S; Andres DA; Spielmann HP; Lammerding J; Wang Y; Young SG; Fong LG
    Hum Mol Genet; 2010 Jul; 19(13):2682-94. PubMed ID: 20421363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The posttranslational processing of prelamin A and disease.
    Davies BS; Fong LG; Yang SH; Coffinier C; Young SG
    Annu Rev Genomics Hum Genet; 2009; 10():153-74. PubMed ID: 19453251
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria.
    Dominici S; Fiori V; Magnani M; Schena E; Capanni C; Camozzi D; D'Apice MR; Le Dour C; Auclair M; Caron M; Novelli G; Vigouroux C; Maraldi NM; Lattanzi G
    Eur J Histochem; 2009; 53(1):43-52. PubMed ID: 19351612
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.
    Gordon LB; Massaro J; D'Agostino RB; Campbell SE; Brazier J; Brown WT; Kleinman ME; Kieran MW;
    Circulation; 2014 Jul; 130(1):27-34. PubMed ID: 24795390
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Compound heterozygosity for mutations in LMNA causes a progeria syndrome without prelamin A accumulation.
    Verstraeten VL; Broers JL; van Steensel MA; Zinn-Justin S; Ramaekers FC; Steijlen PM; Kamps M; Kuijpers HJ; Merckx D; Smeets HJ; Hennekam RC; Marcelis CL; van den Wijngaard A
    Hum Mol Genet; 2006 Aug; 15(16):2509-22. PubMed ID: 16825282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome.
    Mallampalli MP; Huyer G; Bendale P; Gelb MH; Michaelis S
    Proc Natl Acad Sci U S A; 2005 Oct; 102(40):14416-21. PubMed ID: 16186497
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A protein farnesyltransferase inhibitor ameliorates disease in a mouse model of progeria.
    Fong LG; Frost D; Meta M; Qiao X; Yang SH; Coffinier C; Young SG
    Science; 2006 Mar; 311(5767):1621-3. PubMed ID: 16484451
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genomic instability and DNA damage responses in progeria arising from defective maturation of prelamin A.
    Musich PR; Zou Y
    Aging (Albany NY); 2009 Jan; 1(1):28-37. PubMed ID: 19851476
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome.
    Blondel S; Jaskowiak AL; Egesipe AL; Le Corf A; Navarro C; Cordette V; Martinat C; Laabi Y; Djabali K; de Sandre-Giovannoli A; Levy N; Peschanski M; Nissan X
    Stem Cells Transl Med; 2014 Apr; 3(4):510-9. PubMed ID: 24598781
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The truncated prelamin A in Hutchinson-Gilford progeria syndrome alters segregation of A-type and B-type lamin homopolymers.
    Delbarre E; Tramier M; Coppey-Moisan M; Gaillard C; Courvalin JC; Buendia B
    Hum Mol Genet; 2006 Apr; 15(7):1113-22. PubMed ID: 16481358
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lamin A precursor induces barrier-to-autointegration factor nuclear localization.
    Capanni C; Cenni V; Haraguchi T; Squarzoni S; Schüchner S; Ogris E; Novelli G; Maraldi N; Lattanzi G
    Cell Cycle; 2010 Jul; 9(13):2600-10. PubMed ID: 20581439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasion.
    de la Rosa J; Freije JM; Cabanillas R; Osorio FG; Fraga MF; Fernández-García MS; Rad R; Fanjul V; Ugalde AP; Liang Q; Prosser HM; Bradley A; Cadiñanos J; López-Otín C
    Nat Commun; 2013; 4():2268. PubMed ID: 23917225
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Prelamin A, Zmpste24, misshapen cell nuclei, and progeria--new evidence suggesting that protein farnesylation could be important for disease pathogenesis.
    Young SG; Fong LG; Michaelis S
    J Lipid Res; 2005 Dec; 46(12):2531-58. PubMed ID: 16207929
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of LMNA splicing as a strategy to treat prelamin A diseases.
    Lee JM; Nobumori C; Tu Y; Choi C; Yang SH; Jung HJ; Vickers TA; Rigo F; Bennett CF; Young SG; Fong LG
    J Clin Invest; 2016 Apr; 126(4):1592-602. PubMed ID: 26999604
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rejuvenating premature aging.
    Meshorer E; Gruenbaum Y
    Nat Med; 2008 Jul; 14(7):713-5. PubMed ID: 18607367
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.