These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

222 related articles for article (PubMed ID: 19965771)

  • 1. Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage.
    Eccles LJ; Lomax ME; O'Neill P
    Nucleic Acids Res; 2010 Mar; 38(4):1123-34. PubMed ID: 19965771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Processing of thymine glycol in a clustered DNA damage site: mutagenic or cytotoxic.
    Bellon S; Shikazono N; Cunniffe S; Lomax M; O'Neill P
    Nucleic Acids Res; 2009 Jul; 37(13):4430-40. PubMed ID: 19468043
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased mutability and decreased repairability of a three-lesion clustered DNA-damaged site comprised of an AP site and bi-stranded 8-oxoG lesions.
    Cunniffe S; Walker A; Stabler R; O'Neill P; Lomax ME
    Int J Radiat Biol; 2014 Jun; 90(6):468-79. PubMed ID: 24597750
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biological consequences of potential repair intermediates of clustered base damage site in Escherichia coli.
    Shikazono N; O'Neill P
    Mutat Res; 2009 Oct; 669(1-2):162-8. PubMed ID: 19540248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. An AP site can protect against the mutagenic potential of 8-oxoG when present within a tandem clustered site in E. coli.
    Cunniffe SM; Lomax ME; O'Neill P
    DNA Repair (Amst); 2007 Dec; 6(12):1839-49. PubMed ID: 17704010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The mutagenic potential of 8-oxoG/single strand break-containing clusters depends on their relative positions.
    Noguchi M; Urushibara A; Yokoya A; O'Neill P; Shikazono N
    Mutat Res; 2012 Apr; 732(1-2):34-42. PubMed ID: 22261346
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.
    Cunniffe S; O'Neill P; Greenberg MM; Lomax ME
    Mutat Res; 2014 Apr; 762():32-9. PubMed ID: 24631220
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Significance of DNA polymerase I in in vivo processing of clustered DNA damage.
    Shikazono N; Akamatsu K; Takahashi M; Noguchi M; Urushibara A; O'Neill P; Yokoya A
    Mutat Res; 2013 Sep; 749(1-2):9-15. PubMed ID: 23958410
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced mutagenic potential of 8-oxo-7,8-dihydroguanine when present within a clustered DNA damage site.
    Pearson CG; Shikazono N; Thacker J; O'Neill P
    Nucleic Acids Res; 2004; 32(1):263-70. PubMed ID: 14715924
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 8-OxoG retards the activity of the ligase III/XRCC1 complex during the repair of a single-strand break, when present within a clustered DNA damage site.
    Lomax ME; Cunniffe S; O'Neill P
    DNA Repair (Amst); 2004 Mar; 3(3):289-99. PubMed ID: 15177044
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Artemis is required to improve the accuracy of repair of double-strand breaks with 5'-blocked termini generated from non-DSB-clustered lesions.
    Malyarchuk S; Castore R; Shi R; Harrison L
    Mutagenesis; 2013 May; 28(3):357-66. PubMed ID: 23448902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The roles of specific glycosylases in determining the mutagenic consequences of clustered DNA base damage.
    Shikazono N; Pearson C; O'Neill P; Thacker J
    Nucleic Acids Res; 2006; 34(13):3722-30. PubMed ID: 16893955
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Two clustered 8-oxo-7,8-dihydroguanine (8-oxodG) lesions increase the point mutation frequency of 8-oxodG, but do not result in double strand breaks or deletions in Escherichia coli.
    Malyarchuk S; Brame KL; Youngblood R; Shi R; Harrison L
    Nucleic Acids Res; 2004; 32(19):5721-31. PubMed ID: 15509868
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Strand with mutagenic lesion is preferentially used as a template in the region of a bi-stranded clustered DNA damage site in Escherichia coli.
    Shikazono N; Akamatsu K
    Sci Rep; 2020 Jun; 10(1):9737. PubMed ID: 32546758
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Efficient cleavage of single and clustered AP site lesions within mono-nucleosome templates by CHO-K1 nuclear extract contrasts with retardation of incision by purified APE1.
    Eccles LJ; Menoni H; Angelov D; Lomax ME; O'Neill P
    DNA Repair (Amst); 2015 Nov; 35():27-36. PubMed ID: 26439176
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interplay of two major repair pathways in the processing of complex double-strand DNA breaks.
    Dobbs TA; Palmer P; Maniou Z; Lomax ME; O'Neill P
    DNA Repair (Amst); 2008 Aug; 7(8):1372-83. PubMed ID: 18571480
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Replication fork collapse is a major cause of the high mutation frequency at three-base lesion clusters.
    Sedletska Y; Radicella JP; Sage E
    Nucleic Acids Res; 2013 Nov; 41(20):9339-48. PubMed ID: 23945941
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutagenic potential of 8-oxo-7,8-dihydroguanine (8-oxoG) is influenced by nearby clustered lesions.
    Shikazono N; Akamatsu K
    Mutat Res; 2018 Jul; 810():6-12. PubMed ID: 29870902
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Excision of 8-oxoguanine within clustered damage by the yeast OGG1 protein.
    David-Cordonnier MH; Boiteux S; O'Neill P
    Nucleic Acids Res; 2001 Mar; 29(5):1107-13. PubMed ID: 11222760
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recognition and kinetics for excision of a base lesion within clustered DNA damage by the Escherichia coli proteins Fpg and Nth.
    David-Cordonnier MH; Laval J; O'Neill P
    Biochemistry; 2001 May; 40(19):5738-46. PubMed ID: 11341839
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.