BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

337 related articles for article (PubMed ID: 19966290)

  • 1. Role of the translocation partner in protection against AID-dependent chromosomal translocations.
    Jankovic M; Robbiani DF; Dorsett Y; Eisenreich T; Xu Y; Tarakhovsky A; Nussenzweig A; Nussenzweig MC
    Proc Natl Acad Sci U S A; 2010 Jan; 107(1):187-92. PubMed ID: 19966290
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
    Ramiro AR; Jankovic M; Callen E; Difilippantonio S; Chen HT; McBride KM; Eisenreich TR; Chen J; Dickins RA; Lowe SW; Nussenzweig A; Nussenzweig MC
    Nature; 2006 Mar; 440(7080):105-9. PubMed ID: 16400328
    [TBL] [Abstract][Full Text] [Related]  

  • 3. AID-targeting and hypermutation of non-immunoglobulin genes does not correlate with proximity to immunoglobulin genes in germinal center B cells.
    Gramlich HS; Reisbig T; Schatz DG
    PLoS One; 2012; 7(6):e39601. PubMed ID: 22768095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations.
    Robbiani DF; Bothmer A; Callen E; Reina-San-Martin B; Dorsett Y; Difilippantonio S; Bolland DJ; Chen HT; Corcoran AE; Nussenzweig A; Nussenzweig MC
    Cell; 2008 Dec; 135(6):1028-38. PubMed ID: 19070574
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AID produces DNA double-strand breaks in non-Ig genes and mature B cell lymphomas with reciprocal chromosome translocations.
    Robbiani DF; Bunting S; Feldhahn N; Bothmer A; Camps J; Deroubaix S; McBride KM; Klein IA; Stone G; Eisenreich TR; Ried T; Nussenzweig A; Nussenzweig MC
    Mol Cell; 2009 Nov; 36(4):631-41. PubMed ID: 19941823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
    Sluss HK; Gannon H; Coles AH; Shen Q; Eischen CM; Jones SN
    Mol Cancer Res; 2010 Feb; 8(2):216-22. PubMed ID: 20145032
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Developmental propagation of V(D)J recombination-associated DNA breaks and translocations in mature B cells via dicentric chromosomes.
    Hu J; Tepsuporn S; Meyers RM; Gostissa M; Alt FW
    Proc Natl Acad Sci U S A; 2014 Jul; 111(28):10269-74. PubMed ID: 24982162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. AID is required for c-myc/IgH chromosome translocations in vivo.
    Ramiro AR; Jankovic M; Eisenreich T; Difilippantonio S; Chen-Kiang S; Muramatsu M; Honjo T; Nussenzweig A; Nussenzweig MC
    Cell; 2004 Aug; 118(4):431-8. PubMed ID: 15315756
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A role for AID in chromosome translocations between c-myc and the IgH variable region.
    Dorsett Y; Robbiani DF; Jankovic M; Reina-San-Martin B; Eisenreich TR; Nussenzweig MC
    J Exp Med; 2007 Sep; 204(9):2225-32. PubMed ID: 17724134
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.
    White CA; Seth Hawkins J; Pone EJ; Yu ES; Al-Qahtani A; Mai T; Zan H; Casali P
    Autoimmunity; 2011 Dec; 44(8):585-98. PubMed ID: 21585311
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long-range oncogenic activation of Igh-c-myc translocations by the Igh 3' regulatory region.
    Gostissa M; Yan CT; Bianco JM; Cogné M; Pinaud E; Alt FW
    Nature; 2009 Dec; 462(7274):803-7. PubMed ID: 20010689
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
    Maclean KH; Dorsey FC; Cleveland JL; Kastan MB
    J Clin Invest; 2008 Jan; 118(1):79-88. PubMed ID: 18097482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amino-terminal phosphorylation of activation-induced cytidine deaminase suppresses c-myc/IgH translocation.
    Gazumyan A; Timachova K; Yuen G; Siden E; Di Virgilio M; Woo EM; Chait BT; Reina San-Martin B; Nussenzweig MC; McBride KM
    Mol Cell Biol; 2011 Feb; 31(3):442-9. PubMed ID: 21135131
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanisms promoting translocations in editing and switching peripheral B cells.
    Wang JH; Gostissa M; Yan CT; Goff P; Hickernell T; Hansen E; Difilippantonio S; Wesemann DR; Zarrin AA; Rajewsky K; Nussenzweig A; Alt FW
    Nature; 2009 Jul; 460(7252):231-6. PubMed ID: 19587764
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching.
    Wang JH; Alt FW; Gostissa M; Datta A; Murphy M; Alimzhanov MB; Coakley KM; Rajewsky K; Manis JP; Yan CT
    J Exp Med; 2008 Dec; 205(13):3079-90. PubMed ID: 19064702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
    Shreeram S; Hee WK; Demidov ON; Kek C; Yamaguchi H; Fornace AJ; Anderson CW; Appella E; Bulavin DV
    J Exp Med; 2006 Dec; 203(13):2793-9. PubMed ID: 17158963
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations.
    Rowh MA; DeMicco A; Horowitz JE; Yin B; Yang-Iott KS; Fusello AM; Hobeika E; Reth M; Bassing CH
    Oncogene; 2011 Nov; 30(47):4757-64. PubMed ID: 21625223
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53.
    Valente LJ; Grabow S; Vandenberg CJ; Strasser A; Janic A
    Oncogene; 2016 Jul; 35(29):3866-71. PubMed ID: 26640149
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel IGH and MYC Translocation Partners in Diffuse Large B-Cell Lymphomas.
    Otto C; Scholtysik R; Schmitz R; Kreuz M; Becher C; Hummel M; Rosenwald A; Trümper L; Klapper W; Siebert R; Küppers R;
    Genes Chromosomes Cancer; 2016 Dec; 55(12):932-943. PubMed ID: 27356265
    [TBL] [Abstract][Full Text] [Related]  

  • 20. AID and Igh switch region-Myc chromosomal translocations.
    Unniraman S; Schatz DG
    DNA Repair (Amst); 2006 Sep; 5(9-10):1259-64. PubMed ID: 16784901
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.