BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 1998678)

  • 1. Evidence for two interconverting protein isomers in the methotrexate complex of dihydrofolate reductase from Escherichia coli.
    Falzone CJ; Wright PE; Benkovic SJ
    Biochemistry; 1991 Feb; 30(8):2184-91. PubMed ID: 1998678
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 15N NMR studies of the conformation of E. coli dihydrofolate reductase in complex with folate or methotrexate.
    Huang FY; Yang QX; Huang TH
    FEBS Lett; 1991 Sep; 289(2):231-4. PubMed ID: 1915851
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dihydrofolate reductase: sequential resonance assignments using 2D and 3D NMR and secondary structure determination in solution.
    Carr MD; Birdsall B; Frenkiel TA; Bauer CJ; Jimenez-Barbero J; Polshakov VI; McCormick JE; Roberts GC; Feeney J
    Biochemistry; 1991 Jun; 30(25):6330-41. PubMed ID: 1905571
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Partial 1H NMR assignments of the Escherichia coli dihydrofolate reductase complex with folate: evidence for a unique conformation of bound folate.
    Falzone CJ; Benkovic SJ; Wright PE
    Biochemistry; 1990 Oct; 29(41):9667-77. PubMed ID: 2271608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dihydrofolate reductase: multiple conformations and alternative modes of substrate binding.
    Birdsall B; Feeney J; Tendler SJ; Hammond SJ; Roberts GC
    Biochemistry; 1989 Mar; 28(5):2297-305. PubMed ID: 2524214
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proton magnetic resonance studies on Escherichia coli dihydrofolate reductase. Assignment of histidine C-2 protons in binary complexes with folates on the basis of the crystal structure with methotrexate and on chemical modifications.
    Poe M; Hoogsteen K; Matthews DA
    J Biol Chem; 1979 Sep; 254(17):8143-52. PubMed ID: 38247
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 13C NMR studies of complexes of Escherichia coli dihydrofolate reductase formed with methotrexate and with folic acid.
    Cheung HT; Birdsall B; Feeney J
    FEBS Lett; 1992 Nov; 312(2-3):147-51. PubMed ID: 1426244
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4.
    Lee H; Reyes VM; Kraut J
    Biochemistry; 1996 Jun; 35(22):7012-20. PubMed ID: 8679526
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural comparisons of complexes of methotrexate analogues with Lactobacillus casei dihydrofolate reductase by two-dimensional 1H NMR at 500 MHz.
    Hammond SJ; Birdsall B; Feeney J; Searle MS; Roberts GC; Cheung HT
    Biochemistry; 1987 Dec; 26(26):8585-90. PubMed ID: 3126805
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Light activates reduction of methotrexate by NADPH in the ternary complex with Escherichia coli dihydrofolate reductase.
    Chen YQ; Gulotta M; Cheung HT; Callender R
    Photochem Photobiol; 1999 Jan; 69(1):77-85. PubMed ID: 10063803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 19F NMR spectroscopy of [6-19F]tryptophan-labeled Escherichia coli dihydrofolate reductase: equilibrium folding and ligand binding studies.
    Hoeltzli SD; Frieden C
    Biochemistry; 1994 May; 33(18):5502-9. PubMed ID: 8180172
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications.
    Reyes VM; Sawaya MR; Brown KA; Kraut J
    Biochemistry; 1995 Feb; 34(8):2710-23. PubMed ID: 7873554
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Methotrexate and folate binding to dihydrofolate reductase. Separate characterization of the pteridine and p-aminobenzoyl binding sites by resonance Raman spectroscopy.
    Ozaki Y; King RW; Carey PR
    Biochemistry; 1981 May; 20(11):3219-25. PubMed ID: 7018571
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 1H, 15N and 13C resonance assignments, secondary structure, and the conformation of substrate in the binary folate complex of Escherichia coli dihydrofolate reductase.
    Falzone CJ; Cavanagh J; Cowart M; Palmer AG; Matthews CR; Benkovic SJ; Wright PE
    J Biomol NMR; 1994 May; 4(3):349-66. PubMed ID: 8019142
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nuclear magnetic resonance study of the state of protonation of inhibitors bound to mutant dihydrofolate reductase lacking the active-site carboxyl.
    London RE; Howell EE; Warren MS; Kraut J; Blakley RL
    Biochemistry; 1986 Nov; 25(22):7229-35. PubMed ID: 3542023
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Methotrexate binds in a non-productive orientation to human dihydrofolate reductase in solution, based on NMR spectroscopy.
    Stockman BJ; Nirmala NR; Wagner G; Delcamp TJ; DeYarman MT; Freisheim JH
    FEBS Lett; 1991 Jun; 283(2):267-9. PubMed ID: 2044765
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
    Bolin JT; Filman DJ; Matthews DA; Hamlin RC; Kraut J
    J Biol Chem; 1982 Nov; 257(22):13650-62. PubMed ID: 6815178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Dihydrofolate reductase: x-ray structure of the binary complex with methotrexate.
    Matthews DA; Alden RA; Bolin JT; Freer ST; Hamlin R; Xuong N; Kraut J; Poe M; Williams M; Hoogsteen K
    Science; 1977 Jul; 197(4302):452-5. PubMed ID: 17920
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Detection of long-lived bound water molecules in complexes of human dihydrofolate reductase with methotrexate and NADPH.
    Meiering EM; Wagner G
    J Mol Biol; 1995 Mar; 247(2):294-308. PubMed ID: 7707376
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of chicken liver dihydrofolate reductase complexed with NADP+ and biopterin.
    McTigue MA; Davies JF; Kaufman BT; Kraut J
    Biochemistry; 1992 Aug; 31(32):7264-73. PubMed ID: 1510919
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.