387 related articles for article (PubMed ID: 1998680)
1. Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins.
Odake S; Kam CM; Narasimhan L; Poe M; Blake JT; Krahenbuhl O; Tschopp J; Powers JC
Biochemistry; 1991 Feb; 30(8):2217-27. PubMed ID: 1998680
[TBL] [Abstract][Full Text] [Related]
2. Human cytotoxic lymphocyte granzyme B. Its purification from granules and the characterization of substrate and inhibitor specificity.
Poe M; Blake JT; Boulton DA; Gammon M; Sigal NH; Wu JK; Zweerink HJ
J Biol Chem; 1991 Jan; 266(1):98-103. PubMed ID: 1985927
[TBL] [Abstract][Full Text] [Related]
3. The human cytotoxic T cell granule serine protease granzyme H has chymotrypsin-like (chymase) activity and is taken up into cytoplasmic vesicles reminiscent of granzyme B-containing endosomes.
Edwards KM; Kam CM; Powers JC; Trapani JA
J Biol Chem; 1999 Oct; 274(43):30468-73. PubMed ID: 10521426
[TBL] [Abstract][Full Text] [Related]
4. Substrate and inhibitor studies on proteinase 3.
Kam CM; Kerrigan JE; Dolman KM; Goldschmeding R; Von dem Borne AE; Powers JC
FEBS Lett; 1992 Feb; 297(1-2):119-23. PubMed ID: 1551417
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.
Jackson DS; Fraser SA; Ni LM; Kam CM; Winkler U; Johnson DA; Froelich CJ; Hudig D; Powers JC
J Med Chem; 1998 Jun; 41(13):2289-301. PubMed ID: 9632362
[TBL] [Abstract][Full Text] [Related]
6. Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors.
Kam CM; Hudig D; Powers JC
Biochim Biophys Acta; 2000 Mar; 1477(1-2):307-23. PubMed ID: 10708866
[TBL] [Abstract][Full Text] [Related]
7. The function of lymphocyte proteases. Inhibition and restoration of granule-mediated lysis with isocoumarin serine protease inhibitors.
Hudig D; Allison NJ; Pickett TM; Winkler U; Kam CM; Powers JC
J Immunol; 1991 Aug; 147(4):1360-8. PubMed ID: 1869829
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of CPP32-like proteases prevents granzyme B- and Fas-, but not granzyme A-based cytotoxicity exerted by CTL clones.
Anel A; Gamen S; Alava MA; Schmitt-Verhulst AM; PiƱeiro A; Naval J
J Immunol; 1997 Mar; 158(5):1999-2006. PubMed ID: 9036942
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and kinetic studies of diphenyl 1-(N-peptidylamino)alkanephosphonate esters and their biotinylated derivatives as inhibitors of serine proteases and probes for lymphocyte granzymes.
Abuelyaman AS; Jackson DS; Hudig D; Woodard SL; Powers JC
Arch Biochem Biophys; 1997 Aug; 344(2):271-80. PubMed ID: 9264539
[TBL] [Abstract][Full Text] [Related]
10. Mammalian tissue trypsin-like enzymes: substrate specificity and inhibitory potency of substituted isocoumarin mechanism-based inhibitors, benzamidine derivatives, and arginine fluoroalkyl ketone transition-state inhibitors.
Kam CM; Hernandez MA; Patil GS; Ueda T; Simmons WH; Braganza VJ; Powers JC
Arch Biochem Biophys; 1995 Feb; 316(2):808-14. PubMed ID: 7864637
[TBL] [Abstract][Full Text] [Related]
11. Human granzyme B degrades aggrecan proteoglycan in matrix synthesized by chondrocytes.
Froelich CJ; Zhang X; Turbov J; Hudig D; Winkler U; Hanna WL
J Immunol; 1993 Dec; 151(12):7161-71. PubMed ID: 8258716
[TBL] [Abstract][Full Text] [Related]
12. Human complement proteins D, C2, and B. Active site mapping with peptide thioester substrates.
Kam CM; McRae BJ; Harper JW; Niemann MA; Volanakis JE; Powers JC
J Biol Chem; 1987 Mar; 262(8):3444-51. PubMed ID: 3546307
[TBL] [Abstract][Full Text] [Related]
13. The enzymatic activity of human cytotoxic T-lymphocyte granzyme A and cytolysis mediated by cytotoxic T-lymphocytes are potently inhibited by a synthetic antiprotease, FUT-175.
Poe M; Wu JK; Blake JT; Zweerink HJ; Sigal NH
Arch Biochem Biophys; 1991 Jan; 284(1):215-8. PubMed ID: 1989498
[TBL] [Abstract][Full Text] [Related]
14. Subsite specificities of granzyme M: a study of inhibitors and newly synthesized thiobenzyl ester substrates.
Rukamp BJ; Kam CM; Natarajan S; Bolton BW; Smyth MJ; Kelly JM; Powers JC
Arch Biochem Biophys; 2004 Feb; 422(1):9-22. PubMed ID: 14725853
[TBL] [Abstract][Full Text] [Related]
15. Substituted isocoumarins as inhibitors of complement serine proteases.
Kam CM; Oglesby TJ; Pangburn MK; Volanakis JE; Powers JC
J Immunol; 1992 Jul; 149(1):163-8. PubMed ID: 1607651
[TBL] [Abstract][Full Text] [Related]
16. Characterization, application and potential uses of biotin-tagged inhibitors for lymphocyte serine proteases (granzymes).
Winkler U; Allison NJ; Woodard SL; Gault RA; Ewoldt GR; Kam CM; Abuelyaman A; Powers JC; Hudig D
Mol Immunol; 1996; 33(7-8):615-23. PubMed ID: 8760273
[TBL] [Abstract][Full Text] [Related]
17. Active site mapping of the serine proteases human leukocyte elastase, cathepsin G, porcine pancreatic elastase, rat mast cell proteases I and II. Bovine chymotrypsin A alpha, and Staphylococcus aureus protease V-8 using tripeptide thiobenzyl ester substrates.
Harper JW; Cook RR; Roberts CJ; McLaughlin BJ; Powers JC
Biochemistry; 1984 Jun; 23(13):2995-3002. PubMed ID: 6380580
[TBL] [Abstract][Full Text] [Related]
18. A colorimetric assay that specifically measures Granzyme B proteolytic activity: hydrolysis of Boc-Ala-Ala-Asp-S-Bzl.
Hagn M; Sutton VR; Trapani JA
J Vis Exp; 2014 Nov; (93):e52419. PubMed ID: 25489668
[TBL] [Abstract][Full Text] [Related]
19. Lymphocyte granule-mediated cytolysis requires serine protease activity.
Hudig D; Gregg NJ; Kam CM; Powers JC
Biochem Biophys Res Commun; 1987 Dec; 149(3):882-8. PubMed ID: 3480709
[TBL] [Abstract][Full Text] [Related]
20. Expression of recombinant human granzyme B. A processing and activation role for dipeptidyl peptidase I.
Smyth MJ; McGuire MJ; Thia KY
J Immunol; 1995 Jun; 154(12):6299-305. PubMed ID: 7759868
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]