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2. Crystal structures of Escherichia coli dihydrofolate reductase complexed with 5-formyltetrahydrofolate (folinic acid) in two space groups: evidence for enolization of pteridine O4. Lee H; Reyes VM; Kraut J Biochemistry; 1996 Jun; 35(22):7012-20. PubMed ID: 8679526 [TBL] [Abstract][Full Text] [Related]
3. Crystal structures of Escherichia coli dihydrofolate reductase: the NADP+ holoenzyme and the folate.NADP+ ternary complex. Substrate binding and a model for the transition state. Bystroff C; Oatley SJ; Kraut J Biochemistry; 1990 Apr; 29(13):3263-77. PubMed ID: 2185835 [TBL] [Abstract][Full Text] [Related]
4. Isomorphous crystal structures of Escherichia coli dihydrofolate reductase complexed with folate, 5-deazafolate, and 5,10-dideazatetrahydrofolate: mechanistic implications. Reyes VM; Sawaya MR; Brown KA; Kraut J Biochemistry; 1995 Feb; 34(8):2710-23. PubMed ID: 7873554 [TBL] [Abstract][Full Text] [Related]
9. Structural Characterization of Dihydrofolate Reductase Complexes by Top-Down Ultraviolet Photodissociation Mass Spectrometry. Cammarata MB; Thyer R; Rosenberg J; Ellington A; Brodbelt JS J Am Chem Soc; 2015 Jul; 137(28):9128-35. PubMed ID: 26125523 [TBL] [Abstract][Full Text] [Related]
10. Conformational changes in the active site loops of dihydrofolate reductase during the catalytic cycle. Venkitakrishnan RP; Zaborowski E; McElheny D; Benkovic SJ; Dyson HJ; Wright PE Biochemistry; 2004 Dec; 43(51):16046-55. PubMed ID: 15609999 [TBL] [Abstract][Full Text] [Related]
11. Effects of coenzyme binding on histidine residues of Lactobacillus casei dihydrofolate reductase. Gronenborn A; Birdsall B; Hyde EI; Roberts GC; Feeney J; Burgen AS Biochemistry; 1981 Mar; 20(7):1717-22. PubMed ID: 6784757 [TBL] [Abstract][Full Text] [Related]
12. Functional role of a mobile loop of Escherichia coli dihydrofolate reductase in transition-state stabilization. Li L; Falzone CJ; Wright PE; Benkovic SJ Biochemistry; 1992 Sep; 31(34):7826-33. PubMed ID: 1510968 [TBL] [Abstract][Full Text] [Related]
13. 13C NMR studies of complexes of Escherichia coli dihydrofolate reductase formed with methotrexate and with folic acid. Cheung HT; Birdsall B; Feeney J FEBS Lett; 1992 Nov; 312(2-3):147-51. PubMed ID: 1426244 [TBL] [Abstract][Full Text] [Related]
15. 15N NMR studies of the conformation of E. coli dihydrofolate reductase in complex with folate or methotrexate. Huang FY; Yang QX; Huang TH FEBS Lett; 1991 Sep; 289(2):231-4. PubMed ID: 1915851 [TBL] [Abstract][Full Text] [Related]
16. Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH. Cody V; Galitsky N; Luft JR; Pangborn W; Rosowsky A; Queener SF Acta Crystallogr D Biol Crystallogr; 2002 Jun; 58(Pt 6 Pt 2):946-54. PubMed ID: 12037296 [TBL] [Abstract][Full Text] [Related]
17. Interligand Overhauser effects in type II dihydrofolate reductase. Li D; Levy LA; Gabel SA; Lebetkin MS; DeRose EF; Wall MJ; Howell EE; London RE Biochemistry; 2001 Apr; 40(14):4242-52. PubMed ID: 11284680 [TBL] [Abstract][Full Text] [Related]
18. Proton magnetic resonance studies on Escherichia coli dihydrofolate reductase. Assignment of histidine C-2 protons in binary complexes with folates on the basis of the crystal structure with methotrexate and on chemical modifications. Poe M; Hoogsteen K; Matthews DA J Biol Chem; 1979 Sep; 254(17):8143-52. PubMed ID: 38247 [TBL] [Abstract][Full Text] [Related]
19. Affinity labeling of dihydrofolate reductase with an antifolate glyoxal. Johanson RA; Henkin J J Biol Chem; 1985 Feb; 260(3):1465-74. PubMed ID: 3881433 [TBL] [Abstract][Full Text] [Related]
20. Role of water in the catalytic cycle of E. coli dihydrofolate reductase. Shrimpton P; Allemann RK Protein Sci; 2002 Jun; 11(6):1442-51. PubMed ID: 12021443 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]