BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 1998745)

  • 1. Role of the side chain of lanosterol in substrate recognition and catalytic activity of lanosterol 14 alpha-demethylase (cytochrome P-450 (14DM)) of yeast.
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    Biochim Biophys Acta; 1991 Feb; 1081(3):262-6. PubMed ID: 1998745
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol.
    Aoyama Y; Yoshida Y
    Biochem Biophys Res Commun; 1991 Aug; 178(3):1064-71. PubMed ID: 1872829
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deformylation of 32-oxo-24,25-dihydrolanosterol by the purified cytochrome P-45014DM (lanosterol 14 alpha-demethylase) from yeast evidence confirming the intermediate step of lanosterol 14 alpha-demethylation.
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    J Biol Chem; 1989 Nov; 264(31):18502-5. PubMed ID: 2509459
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural analysis of the interaction between the side-chain of substrates and the active site of lanosterol 14 alpha-demethylase (P-450(14)DM) of yeast.
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    Biochim Biophys Acta; 1992 Aug; 1122(3):251-5. PubMed ID: 1504086
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 7-Oxo-24,25-dihydrolanosterol: a novel lanosterol 14 alpha-demethylase (P-45014DM) inhibitor which blocks electron transfer to the oxyferro intermediate.
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    Biochim Biophys Acta; 1987 Dec; 922(3):270-7. PubMed ID: 3318933
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of 24,25-dihydrolanosterol analogs by partially purified cytochrome P-450(14DM) from rat liver microsomes.
    Sonoda Y; Sekigawa Y; Sato Y
    Chem Pharm Bull (Tokyo); 1989 Mar; 37(3):718-22. PubMed ID: 2752483
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The 3-hydroxy group of lanosterol is essential for orienting the substrate site of cytochrome P-450(14DM) (lanosterol 14 alpha- demethylase).
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    Biochim Biophys Acta; 1989 Nov; 1006(2):209-13. PubMed ID: 2688742
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The 4 beta-methyl group of substrate does not affect the activity of lanosterol 14 alpha-demethylase (P-450(14)DM) of yeast: difference between the substrate recognition by yeast and plant sterol 14 alpha-demethylases.
    Aoyama Y; Yoshida Y
    Biochem Biophys Res Commun; 1992 Mar; 183(3):1266-72. PubMed ID: 1567403
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterization of catalytic properties and expression of cytochrome P-450(14DM), lanosterol 14 alpha-demethylase, in rats.
    Endo M; Sonoda Y; Ishida K; Sato Y; Sekigawa Y; Fukuhara M
    Res Commun Mol Pathol Pharmacol; 1994 Sep; 85(3):279-89. PubMed ID: 7827803
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular diversity of sterol 14alpha-demethylase substrates in plants, fungi and humans.
    Lamb DC; Kelly DE; Kelly SL
    FEBS Lett; 1998 Mar; 425(2):263-5. PubMed ID: 9559662
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of the 8-double bond of lanosterol in the enzyme-substrate interaction of cytochrome P-450(14DM) (lanosterol 14 alpha-demethylase).
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    Biochim Biophys Acta; 1989 Feb; 1001(2):196-200. PubMed ID: 2917143
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of 32-hydroxy-24,25-dihydrolanosterol by purified cytochrome P-45014DM from yeast. Evidence for contribution of the cytochrome to whole process of lanosterol 14 alpha-demethylation.
    Aoyama Y; Yoshida Y; Sonoda Y; Sato Y
    J Biol Chem; 1987 Jan; 262(3):1239-43. PubMed ID: 3543000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Isolation and characterization of an altered cytochrome P-450 from a yeast mutant defective in lanosterol 14 alpha-demethylation.
    Aoyama Y; Yoshida Y; Nishino T; Katsuki H; Maitra US; Mohan VP; Sprinson DB
    J Biol Chem; 1987 Oct; 262(29):14260-4. PubMed ID: 3115990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sterol 14 alpha-demethylase and its inhibition: structural considerations on interaction of azole antifungal agents with lanosterol 14 alpha-demethylase (P-450(14DM)) of yeast.
    Yoshida Y; Aoyama Y
    Biochem Soc Trans; 1991 Aug; 19(3):778-82. PubMed ID: 1783215
    [No Abstract]   [Full Text] [Related]  

  • 15. Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions.
    Sheng C; Zhang W; Zhang M; Song Y; Ji H; Zhu J; Yao J; Yu J; Yang S; Zhou Y; Zhu J; Lu J
    J Biomol Struct Dyn; 2004 Aug; 22(1):91-9. PubMed ID: 15214809
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular modelling of lanosterol 14 alpha-demethylase (CYP51) from Saccharomyces cerevisiae via homology with CYP102, a unique bacterial cytochrome P450 isoform: quantitative structure-activity relationships (QSARs) within two related series of antifungal azole derivatives.
    Lewis DF; Wiseman A; Tarbit MH
    J Enzyme Inhib; 1999; 14(3):175-92. PubMed ID: 10445042
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo.
    Swinney DC; So OY; Watson DM; Berry PW; Webb AS; Kertesz DJ; Shelton EJ; Burton PM; Walker KA
    Biochemistry; 1994 Apr; 33(15):4702-13. PubMed ID: 8161528
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism of 32-oxo-24,25-dihydrolanosterols by partially purified cytochrome P-450(14DM) from rat liver microsomes.
    Sonoda Y; Sekigawa Y; Sato Y
    Chem Pharm Bull (Tokyo); 1989 Oct; 37(10):2762-5. PubMed ID: 2611935
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Induction and substrate specificity of the lanosterol 14 alpha-demethylase from Saccharomyces cerevisiae Y222.
    Wright GD; Honek JF
    J Bacteriol; 1991 Feb; 173(3):1035-40. PubMed ID: 1846852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Properties and structural requirements for substrate specificity of cytochrome P-450-dependent obtusifoliol 14 alpha-demethylase from maize (Zea mays) seedlings.
    Taton M; Rahier A
    Biochem J; 1991 Jul; 277 ( Pt 2)(Pt 2):483-92. PubMed ID: 1859375
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.