169 related articles for article (PubMed ID: 19995551)
21. Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions.
den Brave F; Cairo LV; Jagadeesan C; Ruger-Herreros C; Mogk A; Bukau B; Jentsch S
Cell Rep; 2020 Jun; 31(9):107680. PubMed ID: 32492414
[TBL] [Abstract][Full Text] [Related]
22. Progress in pathogenesis studies of spinocerebellar ataxia type 1.
Cummings CJ; Orr HT; Zoghbi HY
Philos Trans R Soc Lond B Biol Sci; 1999 Jun; 354(1386):1079-81. PubMed ID: 10434309
[TBL] [Abstract][Full Text] [Related]
23. A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104.
Cashikar AG; Duennwald M; Lindquist SL
J Biol Chem; 2005 Jun; 280(25):23869-75. PubMed ID: 15845535
[TBL] [Abstract][Full Text] [Related]
24. PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone.
Park SH; Kukushkin Y; Gupta R; Chen T; Konagai A; Hipp MS; Hayer-Hartl M; Hartl FU
Cell; 2013 Jul; 154(1):134-45. PubMed ID: 23791384
[TBL] [Abstract][Full Text] [Related]
25. Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.
Verhoef LG; Lindsten K; Masucci MG; Dantuma NP
Hum Mol Genet; 2002 Oct; 11(22):2689-700. PubMed ID: 12374759
[TBL] [Abstract][Full Text] [Related]
26. Huntington toxicity in yeast model depends on polyglutamine aggregation mediated by a prion-like protein Rnq1.
Meriin AB; Zhang X; He X; Newnam GP; Chernoff YO; Sherman MY
J Cell Biol; 2002 Jun; 157(6):997-1004. PubMed ID: 12058016
[TBL] [Abstract][Full Text] [Related]
27. PML clastosomes prevent nuclear accumulation of mutant ataxin-7 and other polyglutamine proteins.
Janer A; Martin E; Muriel MP; Latouche M; Fujigasaki H; Ruberg M; Brice A; Trottier Y; Sittler A
J Cell Biol; 2006 Jul; 174(1):65-76. PubMed ID: 16818720
[TBL] [Abstract][Full Text] [Related]
28. Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1.
Chen HK; Fernandez-Funez P; Acevedo SF; Lam YC; Kaytor MD; Fernandez MH; Aitken A; Skoulakis EM; Orr HT; Botas J; Zoghbi HY
Cell; 2003 May; 113(4):457-68. PubMed ID: 12757707
[TBL] [Abstract][Full Text] [Related]
29. A cellular system that degrades misfolded proteins and protects against neurodegeneration.
Guo L; Giasson BI; Glavis-Bloom A; Brewer MD; Shorter J; Gitler AD; Yang X
Mol Cell; 2014 Jul; 55(1):15-30. PubMed ID: 24882209
[TBL] [Abstract][Full Text] [Related]
30. Ataxin-1 fusion partners alter polyQ lethality and aggregation.
Rich T; Varadaraj A
PLoS One; 2007 Oct; 2(10):e1014. PubMed ID: 17925862
[TBL] [Abstract][Full Text] [Related]
31. [Polyglutamine-expanded ataxin-3 is degraded by autophagy].
Xiao H; Tang J; Hu Z; Tan J; Tang B; Jiang Z
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2010 Feb; 27(1):23-8. PubMed ID: 20140862
[TBL] [Abstract][Full Text] [Related]
32. Polyglutamine-expanded ataxin-1 recruits Cu/Zn-superoxide dismutase into the nucleus of HeLa cells.
Kim SJ; Kim TS; Kim IY; Hong S; Rhim H; Kang S
Biochem Biophys Res Commun; 2003 Aug; 307(3):660-5. PubMed ID: 12893274
[TBL] [Abstract][Full Text] [Related]
33. Polyglutamine-rich suppressors of huntingtin toxicity act upstream of Hsp70 and Sti1 in spatial quality control of amyloid-like proteins.
Wolfe KJ; Ren HY; Trepte P; Cyr DM
PLoS One; 2014; 9(5):e95914. PubMed ID: 24828240
[TBL] [Abstract][Full Text] [Related]
34. Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation.
Schaffar G; Breuer P; Boteva R; Behrends C; Tzvetkov N; Strippel N; Sakahira H; Siegers K; Hayer-Hartl M; Hartl FU
Mol Cell; 2004 Jul; 15(1):95-105. PubMed ID: 15225551
[TBL] [Abstract][Full Text] [Related]
35. Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice.
Cummings CJ; Sun Y; Opal P; Antalffy B; Mestril R; Orr HT; Dillmann WH; Zoghbi HY
Hum Mol Genet; 2001 Jul; 10(14):1511-8. PubMed ID: 11448943
[TBL] [Abstract][Full Text] [Related]
36. The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.
Yue S; Serra HG; Zoghbi HY; Orr HT
Hum Mol Genet; 2001 Jan; 10(1):25-30. PubMed ID: 11136710
[TBL] [Abstract][Full Text] [Related]
37. The ubiquitin-conjugating enzyme UbcH6 regulates the transcriptional repression activity of the SCA1 gene product ataxin-1.
Lee S; Hong S; Kang S
Biochem Biophys Res Commun; 2008 Aug; 372(4):735-40. PubMed ID: 18519031
[TBL] [Abstract][Full Text] [Related]
38. Polyglutamine length-dependent interaction of Hsp40 and Hsp70 family chaperones with truncated N-terminal huntingtin: their role in suppression of aggregation and cellular toxicity.
Jana NR; Tanaka M; Wang Gh; Nukina N
Hum Mol Genet; 2000 Aug; 9(13):2009-18. PubMed ID: 10942430
[TBL] [Abstract][Full Text] [Related]
39. Analysis of the role of heat shock protein (Hsp) molecular chaperones in polyglutamine disease.
Chai Y; Koppenhafer SL; Bonini NM; Paulson HL
J Neurosci; 1999 Dec; 19(23):10338-47. PubMed ID: 10575031
[TBL] [Abstract][Full Text] [Related]
40. Toward therapeutic targets for SCA3: Insight into the role of Machado-Joseph disease protein ataxin-3 in misfolded proteins clearance.
Li X; Liu H; Fischhaber PL; Tang TS
Prog Neurobiol; 2015 Sep; 132():34-58. PubMed ID: 26123252
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
