455 related articles for article (PubMed ID: 19996169)
1. Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus.
Kim J; Kato M; Beachy PA
Proc Natl Acad Sci U S A; 2009 Dec; 106(51):21666-71. PubMed ID: 19996169
[TBL] [Abstract][Full Text] [Related]
2. Bifurcating action of Smoothened in Hedgehog signaling is mediated by Dlg5.
Chong YC; Mann RK; Zhao C; Kato M; Beachy PA
Genes Dev; 2015 Feb; 29(3):262-76. PubMed ID: 25644602
[TBL] [Abstract][Full Text] [Related]
3. A central region of Gli2 regulates its localization to the primary cilium and transcriptional activity.
Santos N; Reiter JF
J Cell Sci; 2014 Apr; 127(Pt 7):1500-10. PubMed ID: 24463817
[TBL] [Abstract][Full Text] [Related]
4. Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.
Chen MH; Wilson CW; Li YJ; Law KK; Lu CS; Gacayan R; Zhang X; Hui CC; Chuang PT
Genes Dev; 2009 Aug; 23(16):1910-28. PubMed ID: 19684112
[TBL] [Abstract][Full Text] [Related]
5. The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury.
Grzelak CA; Martelotto LG; Sigglekow ND; Patkunanathan B; Ajami K; Calabro SR; Dwyer BJ; Tirnitz-Parker JE; Watkins DN; Warner FJ; Shackel NA; McCaughan GW
J Hepatol; 2014 Jan; 60(1):143-51. PubMed ID: 23978713
[TBL] [Abstract][Full Text] [Related]
6. Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.
Lu J; Chen M; Ren XR; Wang J; Lyerly HK; Barak L; Chen W
PLoS One; 2013; 8(5):e63353. PubMed ID: 23671675
[TBL] [Abstract][Full Text] [Related]
7. Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
Barakat B; Yu L; Lo C; Vu D; De Luca E; Cain JE; Martelotto LG; Dedhar S; Sadler AJ; Wang D; Watkins DN; Hannigan GE
EMBO Rep; 2013 Sep; 14(9):837-44. PubMed ID: 23877428
[TBL] [Abstract][Full Text] [Related]
8. Ciliary Entry of the Hedgehog Transcriptional Activator Gli2 Is Mediated by the Nuclear Import Machinery but Differs from Nuclear Transport in Being Imp-α/β1-Independent.
Torrado B; Graña M; Badano JL; Irigoín F
PLoS One; 2016; 11(8):e0162033. PubMed ID: 27579771
[TBL] [Abstract][Full Text] [Related]
9. The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia.
Caparrós-Martín JA; Valencia M; Reytor E; Pacheco M; Fernandez M; Perez-Aytes A; Gean E; Lapunzina P; Peters H; Goodship JA; Ruiz-Perez VL
Hum Mol Genet; 2013 Jan; 22(1):124-39. PubMed ID: 23026747
[TBL] [Abstract][Full Text] [Related]
10. Impact of the Smoothened inhibitor, IPI-926, on smoothened ciliary localization and Hedgehog pathway activity.
Peluso MO; Campbell VT; Harari JA; Tibbitts TT; Proctor JL; Whitebread N; Conley JM; White KF; Kutok JL; Read MA; McGovern K; Faia KL
PLoS One; 2014; 9(3):e90534. PubMed ID: 24608250
[TBL] [Abstract][Full Text] [Related]
11. The loss of Hh responsiveness by a non-ciliary Gli2 variant.
Liu J; Zeng H; Liu A
Development; 2015 May; 142(9):1651-60. PubMed ID: 25834022
[TBL] [Abstract][Full Text] [Related]
12. Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.
Tuson M; He M; Anderson KV
Development; 2011 Nov; 138(22):4921-30. PubMed ID: 22007132
[TBL] [Abstract][Full Text] [Related]
13. Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.
Wen X; Lai CK; Evangelista M; Hongo JA; de Sauvage FJ; Scales SJ
Mol Cell Biol; 2010 Apr; 30(8):1910-22. PubMed ID: 20154143
[TBL] [Abstract][Full Text] [Related]
14. Hedgehog-stimulated chemotaxis is mediated by smoothened located outside the primary cilium.
Bijlsma MF; Damhofer H; Roelink H
Sci Signal; 2012 Aug; 5(238):ra60. PubMed ID: 22912493
[TBL] [Abstract][Full Text] [Related]
15. Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.
Larkins CE; Aviles GD; East MP; Kahn RA; Caspary T
Mol Biol Cell; 2011 Dec; 22(23):4694-703. PubMed ID: 21976698
[TBL] [Abstract][Full Text] [Related]
16. Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.
Qin J; Lin Y; Norman RX; Ko HW; Eggenschwiler JT
Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1456-61. PubMed ID: 21209331
[TBL] [Abstract][Full Text] [Related]
17. Intraflagellar transport 27 is essential for hedgehog signaling but dispensable for ciliogenesis during hair follicle morphogenesis.
Yang N; Li L; Eguether T; Sundberg JP; Pazour GJ; Chen J
Development; 2015 Jun; 142(12):2194-202. PubMed ID: 26023097
[TBL] [Abstract][Full Text] [Related]
18. A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes.
Tukachinsky H; Lopez LV; Salic A
J Cell Biol; 2010 Oct; 191(2):415-28. PubMed ID: 20956384
[TBL] [Abstract][Full Text] [Related]
19. Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors.
Lee SJ; Do IG; Lee J; Kim KM; Jang J; Sohn I; Kang WK
Target Oncol; 2013 Dec; 8(4):271-80. PubMed ID: 23371028
[TBL] [Abstract][Full Text] [Related]
20. Smoothened adopts multiple active and inactive conformations capable of trafficking to the primary cilium.
Wilson CW; Chen MH; Chuang PT
PLoS One; 2009; 4(4):e5182. PubMed ID: 19365551
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]