588 related articles for article (PubMed ID: 19997493)
1. Stoichiometry of base excision repair proteins correlates with increased somatic CAG instability in striatum over cerebellum in Huntington's disease transgenic mice.
Goula AV; Berquist BR; Wilson DM; Wheeler VC; Trottier Y; Merienne K
PLoS Genet; 2009 Dec; 5(12):e1000749. PubMed ID: 19997493
[TBL] [Abstract][Full Text] [Related]
2. The nucleotide sequence, DNA damage location, and protein stoichiometry influence the base excision repair outcome at CAG/CTG repeats.
Goula AV; Pearson CE; Della Maria J; Trottier Y; Tomkinson AE; Wilson DM; Merienne K
Biochemistry; 2012 May; 51(18):3919-32. PubMed ID: 22497302
[TBL] [Abstract][Full Text] [Related]
3. Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal.
Beaver JM; Lai Y; Rolle SJ; Liu Y
DNA Repair (Amst); 2016 Dec; 48():17-29. PubMed ID: 27793507
[TBL] [Abstract][Full Text] [Related]
4. Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liver.
Lee JM; Pinto RM; Gillis T; St Claire JC; Wheeler VC
PLoS One; 2011; 6(8):e23647. PubMed ID: 21897851
[TBL] [Abstract][Full Text] [Related]
5. Transcription elongation and tissue-specific somatic CAG instability.
Goula AV; Stys A; Chan JP; Trottier Y; Festenstein R; Merienne K
PLoS Genet; 2012; 8(11):e1003051. PubMed ID: 23209427
[TBL] [Abstract][Full Text] [Related]
6. Base excision repair of oxidative DNA damage coupled with removal of a CAG repeat hairpin attenuates trinucleotide repeat expansion.
Xu M; Lai Y; Torner J; Zhang Y; Zhang Z; Liu Y
Nucleic Acids Res; 2014 Apr; 42(6):3675-91. PubMed ID: 24423876
[TBL] [Abstract][Full Text] [Related]
7. Haploinsufficiency of yeast FEN1 causes instability of expanded CAG/CTG tracts in a length-dependent manner.
Yang J; Freudenreich CH
Gene; 2007 May; 393(1-2):110-5. PubMed ID: 17383831
[TBL] [Abstract][Full Text] [Related]
8. MSH3 polymorphisms and protein levels affect CAG repeat instability in Huntington's disease mice.
Tomé S; Manley K; Simard JP; Clark GW; Slean MM; Swami M; Shelbourne PF; Tillier ER; Monckton DG; Messer A; Pearson CE
PLoS Genet; 2013; 9(2):e1003280. PubMed ID: 23468640
[TBL] [Abstract][Full Text] [Related]
9. Expression levels of DNA replication and repair genes predict regional somatic repeat instability in the brain but are not altered by polyglutamine disease protein expression or age.
Mason AG; Tomé S; Simard JP; Libby RT; Bammler TK; Beyer RP; Morton AJ; Pearson CE; La Spada AR
Hum Mol Genet; 2014 Mar; 23(6):1606-18. PubMed ID: 24191263
[TBL] [Abstract][Full Text] [Related]
10. Modifiers of Somatic Repeat Instability in Mouse Models of Friedreich Ataxia and the Fragile X-Related Disorders: Implications for the Mechanism of Somatic Expansion in Huntington's Disease.
Zhao X; Kumari D; Miller CJ; Kim GY; Hayward B; Vitalo AG; Pinto RM; Usdin K
J Huntingtons Dis; 2021; 10(1):149-163. PubMed ID: 33579860
[TBL] [Abstract][Full Text] [Related]
11. Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
Ishiguro H; Yamada K; Sawada H; Nishii K; Ichino N; Sawada M; Kurosawa Y; Matsushita N; Kobayashi K; Goto J; Hashida H; Masuda N; Kanazawa I; Nagatsu T
J Neurosci Res; 2001 Aug; 65(4):289-97. PubMed ID: 11494364
[TBL] [Abstract][Full Text] [Related]
12. Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative.
Fossale E; Seong IS; Coser KR; Shioda T; Kohane IS; Wheeler VC; Gusella JF; MacDonald ME; Lee JM
Hum Mol Genet; 2011 Nov; 20(21):4258-67. PubMed ID: 21840924
[TBL] [Abstract][Full Text] [Related]
13. Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Kovalenko M; Dragileva E; St Claire J; Gillis T; Guide JR; New J; Dong H; Kucherlapati R; Kucherlapati MH; Ehrlich ME; Lee JM; Wheeler VC
PLoS One; 2012; 7(9):e44273. PubMed ID: 22970194
[TBL] [Abstract][Full Text] [Related]
14. DNA base excision repair: a mechanism of trinucleotide repeat expansion.
Liu Y; Wilson SH
Trends Biochem Sci; 2012 Apr; 37(4):162-72. PubMed ID: 22285516
[TBL] [Abstract][Full Text] [Related]
15. A SCA7 CAG/CTG repeat expansion is stable in Drosophila melanogaster despite modulation of genomic context and gene dosage.
Jackson SM; Whitworth AJ; Greene JC; Libby RT; Baccam SL; Pallanck LJ; La Spada AR
Gene; 2005 Feb; 347(1):35-41. PubMed ID: 15715978
[TBL] [Abstract][Full Text] [Related]
16. Coordination between polymerase beta and FEN1 can modulate CAG repeat expansion.
Liu Y; Prasad R; Beard WA; Hou EW; Horton JK; McMurray CT; Wilson SH
J Biol Chem; 2009 Oct; 284(41):28352-28366. PubMed ID: 19674974
[TBL] [Abstract][Full Text] [Related]
17. R-loops promote trinucleotide repeat deletion through DNA base excision repair enzymatic activities.
Laverde EE; Lai Y; Leng F; Balakrishnan L; Freudenreich CH; Liu Y
J Biol Chem; 2020 Oct; 295(40):13902-13913. PubMed ID: 32763971
[TBL] [Abstract][Full Text] [Related]
18. A chemical and kinetic perspective on base excision repair of DNA.
Schermerhorn KM; Delaney S
Acc Chem Res; 2014 Apr; 47(4):1238-46. PubMed ID: 24646203
[TBL] [Abstract][Full Text] [Related]
19. Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Pinto RM; Dragileva E; Kirby A; Lloret A; Lopez E; St Claire J; Panigrahi GB; Hou C; Holloway K; Gillis T; Guide JR; Cohen PE; Li GM; Pearson CE; Daly MJ; Wheeler VC
PLoS Genet; 2013 Oct; 9(10):e1003930. PubMed ID: 24204323
[TBL] [Abstract][Full Text] [Related]
20. DNA polymerase θ promotes CAG•CTG repeat expansions in Huntington's disease via insertion sequences of its catalytic domain.
Chan KY; Li X; Ortega J; Gu L; Li GM
J Biol Chem; 2021 Oct; 297(4):101144. PubMed ID: 34473992
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
