BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 20005103)

  • 1. Synthesis and in vivo evaluation of bicyclic gababutins.
    Blakemore DC; Bryans JS; Carnell P; Carr CL; Chessum NE; Field MJ; Kinsella N; Osborne SA; Warren AN; Williams SC
    Bioorg Med Chem Lett; 2010 Jan; 20(2):461-4. PubMed ID: 20005103
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and in vivo evaluation of 3,4-disubstituted gababutins.
    Blakemore DC; Bryans JS; Carnell P; Field MJ; Kinsella N; Kinsora JK; Meltzer LT; Osborne SA; Thompson LR; Williams SC
    Bioorg Med Chem Lett; 2010 Jan; 20(1):248-51. PubMed ID: 19910190
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vivo evaluation of 3-substituted gababutins.
    Blakemore DC; Bryans JS; Carnell P; Chessum NE; Field MJ; Kinsella N; Kinsora JK; Osborne SA; Williams SC
    Bioorg Med Chem Lett; 2010 Jan; 20(1):362-5. PubMed ID: 19897364
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel cyclopropyl beta-amino acid analogues of pregabalin and gabapentin that target the alpha2-delta protein.
    Schwarz JB; Gibbons SE; Graham SR; Colbry NL; Guzzo PR; Le VD; Vartanian MG; Kinsora JJ; Lotarski SM; Li Z; Dickerson MR; Su TZ; Weber ML; El-Kattan A; Thorpe AJ; Donevan SD; Taylor CP; Wustrow DJ
    J Med Chem; 2005 Apr; 48(8):3026-35. PubMed ID: 15828841
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carboxylate bioisosteres of gabapentin.
    Burgos-Lepley CE; Thompson LR; Kneen CO; Osborne SA; Bryans JS; Capiris T; Suman-Chauhan N; Dooley DJ; Donovan CM; Field MJ; Vartanian MG; Kinsora JJ; Lotarski SM; El-Kattan A; Walters K; Cherukury M; Taylor CP; Wustrow DJ; Schwarz JB
    Bioorg Med Chem Lett; 2006 May; 16(9):2333-6. PubMed ID: 15946842
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Decarbonylative radical coupling of α-aminoacyl tellurides: single-step preparation of γ-amino and α,β-diamino acids and rapid synthesis of gabapentin and manzacidin A.
    Nagatomo M; Nishiyama H; Fujino H; Inoue M
    Angew Chem Int Ed Engl; 2015 Jan; 54(5):1537-41. PubMed ID: 25504989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Carboxylate bioisosteres of pregabalin.
    Schwarz JB; Colbry NL; Zhu Z; Nichelson B; Barta NS; Lin K; Hudack RA; Gibbons SE; Galatsis P; DeOrazio RJ; Manning DD; Vartanian MG; Kinsora JJ; Lotarski SM; Li Z; Dickerson MR; El-Kattan A; Thorpe AJ; Donevan SD; Taylor CP; Wustrow DJ
    Bioorg Med Chem Lett; 2006 Jul; 16(13):3559-63. PubMed ID: 16621528
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and preliminary evaluation of gabapentin-pregabalin mutual prodrugs in relieving neuropathic pain.
    Shi W; Liu H; Zhang Y; Zhong B; Yang H
    Arch Pharm (Weinheim); 2005 Aug; 338(8):358-64. PubMed ID: 16041834
    [TBL] [Abstract][Full Text] [Related]  

  • 9. [Mirogabalin: The next pregabalin?].
    Alcántara Montero A; Ibor Vidal PJ
    Semergen; 2017 Oct; 43(7):e61-e63. PubMed ID: 27773622
    [No Abstract]   [Full Text] [Related]  

  • 10. Synthesis of bicyclic tertiary alpha-amino acids.
    Strachan JP; Whitaker RC; Miller CH; Bhatti BS
    J Org Chem; 2006 Dec; 71(26):9909-11. PubMed ID: 17168622
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of catalytic alkali metal bromide on Hofmann-type rearrangement of imides.
    Moriyama K; Ishida K; Togo H
    Chem Commun (Camb); 2012 Sep; 48(68):8574-6. PubMed ID: 22806230
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Part 2: Design, synthesis and evaluation of hydroxyproline-derived α2δ ligands.
    Rawson DJ; Brugier D; Harrison A; Hough J; Newman J; Otterburn J; Maw GN; Price J; Thompson LR; Turnpenny P; Warren AN
    Bioorg Med Chem Lett; 2011 Jun; 21(12):3767-70. PubMed ID: 21550803
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of gabapentin derivates on mechanical allodynia-like behaviour in a rat model of chronic sciatic constriction injury.
    Hong-Ju Y; He L; Wei-Guo S; Nan Z; Wei-Xiu Y; Zhong-Wei J; Jun-Wei W; Zheng-Hua G; Bo-Hua Z; Zhi-Pu L; Zhe-Hui G
    Bioorg Med Chem Lett; 2004 May; 14(10):2537-41. PubMed ID: 15109646
    [TBL] [Abstract][Full Text] [Related]  

  • 14. XP13512 [(+/-)-1-([(alpha-isobutanoyloxyethoxy)carbonyl] aminomethyl)-1-cyclohexane acetic acid], a novel gabapentin prodrug: I. Design, synthesis, enzymatic conversion to gabapentin, and transport by intestinal solute transporters.
    Cundy KC; Branch R; Chernov-Rogan T; Dias T; Estrada T; Hold K; Koller K; Liu X; Mann A; Panuwat M; Raillard SP; Upadhyay S; Wu QQ; Xiang JN; Yan H; Zerangue N; Zhou CX; Barrett RW; Gallop MA
    J Pharmacol Exp Ther; 2004 Oct; 311(1):315-23. PubMed ID: 15146028
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationships of pregabalin and analogues that target the alpha(2)-delta protein.
    Belliotti TR; Capiris T; Ekhato IV; Kinsora JJ; Field MJ; Heffner TG; Meltzer LT; Schwarz JB; Taylor CP; Thorpe AJ; Vartanian MG; Wise LD; Zhi-Su T; Weber ML; Wustrow DJ
    J Med Chem; 2005 Apr; 48(7):2294-307. PubMed ID: 15801823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A novel highly selective chiral auxiliary for the asymmetric synthesis of L- and D-alpha-amino acid derivatives via a multicomponent Ugi reaction.
    Basso A; Banfi L; Riva R; Guanti G
    J Org Chem; 2005 Jan; 70(2):575-9. PubMed ID: 15651804
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Population Pharmacokinetic Modelling of Morphine, Gabapentin and their Combination in the Rat.
    Papathanasiou T; Juul RV; Gabel-Jensen C; Kreilgaard M; Lund TM
    Pharm Res; 2016 Nov; 33(11):2630-43. PubMed ID: 27380190
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bicyclo[3.2.0]heptane as a Core Structure for Conformational Locking of 1,3-Bis-Pharmacophores, Exemplified by GABA.
    Vorberg R; Trapp N; Carreira EM; Müller K
    Chemistry; 2017 Mar; 23(13):3126-3138. PubMed ID: 27976829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Alpha-aminocyclic and bicyclic alkane carboxylic acids: differential effects on selected amino acids of rat brain cortex.
    Zand R; Sellinger OZ; Water R; Harris R
    J Neurochem; 1974 Dec; 23(6):1201-6. PubMed ID: 4452902
    [No Abstract]   [Full Text] [Related]  

  • 20. C9 helices and ribbons in gamma-peptides: crystal structures of gabapentin oligomers.
    Vasudev PG; Shamala N; Ananda K; Balaram P
    Angew Chem Int Ed Engl; 2005 Aug; 44(31):4972-5. PubMed ID: 16003813
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 8.