106 related articles for article (PubMed ID: 20005726)
21. Three-dimensional structure-activity relationship study of belactosin A and its stereo- and regioisomers: development of potent proteasome inhibitors by a stereochemical diversity-oriented strategy.
Yoshida K; Yamaguchi K; Mizuno A; Unno Y; Asai A; Sone T; Yokosawa H; Matsuda A; Arisawa M; Shuto S
Org Biomol Chem; 2009 May; 7(9):1868-77. PubMed ID: 19590782
[TBL] [Abstract][Full Text] [Related]
22. Design, synthesis and evaluation of potent thymidylate synthase X inhibitors.
Esra Onen F; Boum Y; Jacquement C; Spanedda MV; Jaber N; Scherman D; Myllykallio H; Herscovici J
Bioorg Med Chem Lett; 2008 Jun; 18(12):3628-31. PubMed ID: 18513963
[TBL] [Abstract][Full Text] [Related]
23. Homonojirimycin isomers and N-alkylated homonojirimycins: structural and conformational basis of inhibition of glycosidases.
Asano N; Nishida M; Kato A; Kizu H; Matsui K; Shimada Y; Itoh T; Baba M; Watson AA; Nash RJ; Lilley PM; Watkin DJ; Fleet GW
J Med Chem; 1998 Jul; 41(14):2565-71. PubMed ID: 9651160
[TBL] [Abstract][Full Text] [Related]
24. Synthesis and biological evaluation of heterocycle containing adamantane 11beta-HSD1 inhibitors.
Yeh VS; Patel JR; Yong H; Kurukulasuriya R; Fung S; Monzon K; Chiou W; Wang J; Stolarik D; Imade H; Beno D; Brune M; Jacobson P; Sham H; Link JT
Bioorg Med Chem Lett; 2006 Oct; 16(20):5414-9. PubMed ID: 16899366
[TBL] [Abstract][Full Text] [Related]
25. Discovery of BI 99179, a potent and selective inhibitor of type I fatty acid synthase with central exposure.
Kley JT; Mack J; Hamilton B; Scheuerer S; Redemann N
Bioorg Med Chem Lett; 2011 Oct; 21(19):5924-7. PubMed ID: 21873051
[TBL] [Abstract][Full Text] [Related]
26. Conformationally locked thiosugars as potent alpha-mannosidase inhibitors: synthesis, biochemical and docking studies.
Sivapriya K; Hariharaputran S; Suhas VL; Chandra N; Chandrasekaran S
Bioorg Med Chem; 2007 Sep; 15(17):5659-65. PubMed ID: 17574420
[TBL] [Abstract][Full Text] [Related]
27. Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors.
Verdoes M; Florea BI; van der Linden WA; Renou D; van den Nieuwendijk AM; van der Marel GA; Overkleeft HS
Org Biomol Chem; 2007 May; 5(9):1416-26. PubMed ID: 17464411
[TBL] [Abstract][Full Text] [Related]
28. Synthesis and evaluation of a difluoromethylene analogue of sphingomyelin as an inhibitor of sphingomyelinase.
Yokomatsu T; Takechi H; Akiyama T; Shibuya S; Kominato T; Soeda S; Shimeno H
Bioorg Med Chem Lett; 2001 May; 11(10):1277-80. PubMed ID: 11392536
[TBL] [Abstract][Full Text] [Related]
29. Design and synthesis of novel metalloproteinase inhibitors.
Nakatani S; Ikura M; Yamamoto S; Nishita Y; Itadani S; Habashita H; Sugiura T; Ogawa K; Ohno H; Takahashi K; Nakai H; Toda M
Bioorg Med Chem; 2006 Aug; 14(15):5402-22. PubMed ID: 16621578
[TBL] [Abstract][Full Text] [Related]
30. Neutral sphingomyelinase-inhibiting guanidines prevent herpes simplex virus-1 replication.
Amtmann E; Zöller M; Schilling G
Drugs Exp Clin Res; 2000; 26(2):57-65. PubMed ID: 10894556
[TBL] [Abstract][Full Text] [Related]
31. Synthesis of sphingomyelin sulfur analogue and its behavior toward sphingomyelinase.
Hakogi T; Fujii S; Morita M; Ikeda K; Katsumura S
Bioorg Med Chem Lett; 2005 Apr; 15(8):2141-4. PubMed ID: 15808485
[TBL] [Abstract][Full Text] [Related]
32. The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Hu LY; Boxer PA; Kesten SR; Lei HJ; Wustrow DJ; Moreland DW; Zhang L; Ahn K; Ryder TR; Liu X; Rubin JR; Fahnoe K; Carroll RT; Dutta S; Fahnoe DC; Probert AW; Roof RL; Rafferty MF; Kostlan CR; Scholten JD; Hood M; Ren XD; Schielke GP; Su TZ; Taylor CP; Mistry A; McConnell P; Hasemann C; Ohren J
Bioorg Med Chem Lett; 2006 May; 16(9):2337-40. PubMed ID: 16143519
[TBL] [Abstract][Full Text] [Related]
33. Synthesis and biological evaluation of acyclic triaryl (Z)-olefins possessing a 3,5-di-tert-butyl-4-hydroxyphenyl pharmacophore: dual inhibitors of cyclooxygenases and lipoxygenases.
Moreau A; Rao PN; Knaus EE
Bioorg Med Chem; 2006 Aug; 14(15):5340-50. PubMed ID: 16677817
[TBL] [Abstract][Full Text] [Related]
34. [(S)-gamma-(Arylamino)prolyl]thiazolidine compounds as a novel series of potent and stable DPP-IV inhibitors.
Sakashita H; Akahoshi F; Kitajima H; Tsutsumiuchi R; Hayashi Y
Bioorg Med Chem; 2006 Jun; 14(11):3662-71. PubMed ID: 16460948
[TBL] [Abstract][Full Text] [Related]
35. Semicarbazone-based inhibitors of cathepsin K, are they prodrugs for aldehyde inhibitors?
Adkison KK; Barrett DG; Deaton DN; Gampe RT; Hassell AM; Long ST; McFadyen RB; Miller AB; Miller LR; Payne JA; Shewchuk LM; Wells-Knecht KJ; Willard DH; Wright LL
Bioorg Med Chem Lett; 2006 Feb; 16(4):978-83. PubMed ID: 16290936
[TBL] [Abstract][Full Text] [Related]
36. Dipeptide nitrile inhibitors of cathepsin K.
Altmann E; Aichholz R; Betschart C; Buhl T; Green J; Lattmann R; Missbach M
Bioorg Med Chem Lett; 2006 May; 16(9):2549-54. PubMed ID: 16480867
[TBL] [Abstract][Full Text] [Related]
37. Structure-based design of lipophilic quinazoline inhibitors of thymidylate synthase.
Jones TR; Varney MD; Webber SE; Lewis KK; Marzoni GP; Palmer CL; Kathardekar V; Welsh KM; Webber S; Matthews DA; Appelt K; Smith WW; Janson CA; Villafranca JE; Bacquet RJ; Howland EF; Booth CL; Herrmann SM; Ward RW; White J; Moomaw EW; Bartlett CA; Morse CA
J Med Chem; 1996 Feb; 39(4):904-17. PubMed ID: 8632414
[TBL] [Abstract][Full Text] [Related]
38. Concise approach to the carbocyclic core of the naturally occurring sphingomyelinase inhibitor scyphostatin.
Mehta G; Modugu NR
J Org Chem; 2013 Apr; 78(7):3367-73. PubMed ID: 23442124
[TBL] [Abstract][Full Text] [Related]
39. Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model.
Yang K; Nong K; Gu Q; Dong J; Wang J
Eur J Med Chem; 2018 May; 151():389-400. PubMed ID: 29649738
[TBL] [Abstract][Full Text] [Related]
40. Enantio- and diastereoselective total synthesis of EI-1941-1, -2, and -3, inhibitors of interleukin-1beta converting enzyme, and biological properties of their derivatives.
Shoji M; Uno T; Kakeya H; Onose R; Shiina I; Osada H; Hayashi Y
J Org Chem; 2005 Nov; 70(24):9905-15. PubMed ID: 16292821
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
