BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 20006596)

  • 1. Pharmacological profile of the NOP agonist and cough suppressing agent SCH 486757 (8-[Bis(2-Chlorophenyl)Methyl]-3-(2-Pyrimidinyl)-8-Azabicyclo[3.2.1]Octan-3-Ol) in preclinical models.
    McLeod RL; Tulshian DB; Bolser DC; Varty GB; Baptista M; Fernandez X; Parra LE; Zimmer JC; Erickson CH; Ho GD; Jia Y; Ng FW; Korfmacher W; Xu X; Veals J; Smith-Torhan A; Wainhaus S; Fawzi AB; Austin TM; van Heek M; Hey JA
    Eur J Pharmacol; 2010 Mar; 630(1-3):112-20. PubMed ID: 20006596
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of a novel NOP receptor agonist (SCH 225288) on guinea pig irritant-evoked, feline mechanically induced and canine infectious tracheobronchitis cough.
    McLeod RL; Tulshian DB; Ho GD; Fernandez X; Bolser DC; Parra LE; Zimmer JC; Erickson CH; Fawzi AB; Jayappa H; Lehr C; Erskine J; Smith-Torhan A; Zhang H; Hey JA
    Pharmacology; 2009; 84(3):153-61. PubMed ID: 19696521
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The anxiolytic-like effects of the novel, orally active nociceptin opioid receptor agonist 8-[bis(2-methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510).
    Varty GB; Lu SX; Morgan CA; Cohen-Williams ME; Hodgson RA; Smith-Torhan A; Zhang H; Fawzi AB; Graziano MP; Ho GD; Matasi J; Tulshian D; Coffin VL; Carey GJ
    J Pharmacol Exp Ther; 2008 Aug; 326(2):672-82. PubMed ID: 18492950
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.
    McLeod RL; Jia Y; Fernandez X; Parra LE; Wang X; Tulshian DB; Kiselgof EJ; Tan Z; Fawzi AB; Smith-Torhan A; Zhang H; Hey JA
    Pharmacology; 2004 Jul; 71(3):143-9. PubMed ID: 15161996
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The anxiolytic-like profile of the nociceptin receptor agonist, endo-8-[bis(2-chlorophenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octane-3-carboxamide (SCH 655842): comparison of efficacy and side effects across rodent species.
    Lu SX; Higgins GA; Hodgson RA; Hyde LA; Del Vecchio RA; Guthrie DH; Kazdoba T; McCool MF; Morgan CA; Bercovici A; Ho GD; Tulshian D; Parker EM; Hunter JC; Varty GB
    Eur J Pharmacol; 2011 Jul; 661(1-3):63-71. PubMed ID: 21545797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Where are the new cough treatments: a debriefing of recent clinical proof-of-concept trials with the NOP agonist SCH 486757.
    McLeod RL; Tulshian DB; Sadeh J
    Pharmacology; 2011; 88(1-2):50-4. PubMed ID: 21757975
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.
    Witkin JM; Statnick MA; Rorick-Kehn LM; Pintar JE; Ansonoff M; Chen Y; Tucker RC; Ciccocioppo R
    Pharmacol Ther; 2014 Mar; 141(3):283-99. PubMed ID: 24189487
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors.
    McLeod RL; Parra LE; Mutter JC; Erickson CH; Carey GJ; Tulshian DB; Fawzi AB; Smith-Torhan A; Egan RW; Cuss FM; Hey JA
    Br J Pharmacol; 2001 Mar; 132(6):1175-8. PubMed ID: 11250866
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Antitussive effect of nociceptin/orphanin FQ in experimental cough models.
    McLeod RL; Bolser DC; Jia Y; Parra LE; Mutter JC; Wang X; Tulshian DB; Egan RW; Hey JA
    Pulm Pharmacol Ther; 2002; 15(3):213-6. PubMed ID: 12099766
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-inflammatory and antinociceptive action of an orally available nociceptin receptor agonist SCH 221510 in a mouse model of inflammatory bowel diseases.
    Sobczak M; Mokrowiecka A; Cygankiewicz AI; Zakrzewski PK; Sałaga M; Storr M; Kordek R; Małecka-Panas E; Krajewska WM; Fichna J
    J Pharmacol Exp Ther; 2014 Mar; 348(3):401-9. PubMed ID: 24345466
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of two novel metabolites of SCH 486757, a nociceptin/orphanin FQ peptide receptor agonist, in humans.
    Penner NA; Ho G; Bercovici A; Chowdhury SK; Alton KB
    Drug Metab Dispos; 2010 Nov; 38(11):2067-74. PubMed ID: 20671096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulating cough through modulation of sensory nerve function in the airways.
    Spina D; Page CP
    Pulm Pharmacol Ther; 2013 Oct; 26(5):486-90. PubMed ID: 23524012
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Roles of μ-opioid receptors and nociceptin/orphanin FQ peptide receptors in buprenorphine-induced physiological responses in primates.
    Cremeans CM; Gruley E; Kyle DJ; Ko MC
    J Pharmacol Exp Ther; 2012 Oct; 343(1):72-81. PubMed ID: 22743574
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of the NOP agonist SCH221510 on producing and attenuating reinforcing effects as measured by drug self-administration in rats.
    Sukhtankar DD; Lagorio CH; Ko MC
    Eur J Pharmacol; 2014 Dec; 745():182-9. PubMed ID: 25446568
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of spinally administered bifunctional nociceptin/orphanin FQ peptide receptor/μ-opioid receptor ligands in mouse models of neuropathic and inflammatory pain.
    Sukhtankar DD; Zaveri NT; Husbands SM; Ko MC
    J Pharmacol Exp Ther; 2013 Jul; 346(1):11-22. PubMed ID: 23652222
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of stimulation of mu opioid and nociceptin/orphanin FQ peptide (NOP) receptors on alcohol drinking in rhesus monkeys.
    Flynn SM; Epperly PM; Davenport AT; Cami-Kobeci G; Husbands SM; Ko MC; Czoty PW
    Neuropsychopharmacology; 2019 Jul; 44(8):1476-1484. PubMed ID: 30970376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of orally active 3-pyridinyl-tropane as a potent nociceptin receptor agonist for the management of cough.
    Yang SW; Ho G; Tulshian D; Greenlee WJ; Anthes J; Fernandez X; McLeod RL; Hey JA; Xu X
    J Med Chem; 2009 Sep; 52(17):5323-9. PubMed ID: 19678644
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Peripheral and central sites of action of GABA-B agonists to inhibit the cough reflex in the cat and guinea pig.
    Bolser DC; DeGennaro FC; O'Reilly S; Chapman RW; Kreutner W; Egan RW; Hey JA
    Br J Pharmacol; 1994 Dec; 113(4):1344-8. PubMed ID: 7889290
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of the NOP receptor agonist Ro65-6570 on the acquisition of opiate- and psychostimulant-induced conditioned place preference in rats.
    Rutten K; De Vry J; Bruckmann W; Tzschentke TM
    Eur J Pharmacol; 2010 Oct; 645(1-3):119-26. PubMed ID: 20674566
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antitussive effects of GABAB agonists in the cat and guinea-pig.
    Bolser DC; Aziz SM; DeGennaro FC; Kreutner W; Egan RW; Siegel MI; Chapman RW
    Br J Pharmacol; 1993 Sep; 110(1):491-5. PubMed ID: 8220912
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.